{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T23:50:32Z","timestamp":1791589832358,"version":"4.3.4"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T00:00:00Z","timestamp":1713484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001505","name":"Health Research Council of New Zealand","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001505","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001516","name":"National Heart Foundation of New Zealand","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001516","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.ijcard.2024.132071","type":"journal-article","created":{"date-parts":[[2024,4,20]],"date-time":"2024-04-20T05:57:19Z","timestamp":1713592639000},"page":"132071","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Prognostic performance of soluble urokinase plasminogen activator receptor for heart failure or mortality in Western and Asian patients with acute breathlessness"],"prefix":"10.1016","volume":"406","author":[{"given":"Janice","family":"Chew-Harris","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Frampton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Greer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Appleby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John W.","family":"Pickering","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Win Sen","family":"Kuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irwani","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siew Pang","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zisheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oi Wah","family":"Liew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip D.","family":"Adamson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Troughton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li Ling","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiqin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirley Beng Suat","family":"Ooi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Mark","family":"Richards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Pemberton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.ijcard.2024.132071_bb0005","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1002\/ejhf.2595","article-title":"Long-term survival and life expectancy following an acute heart failure hospitalization in Australia and New Zealand","volume":"24","author":"Hariharaputhiran","year":"2022","journal-title":"Eur. J. Heart Fail."},{"issue":"3","key":"10.1016\/j.ijcard.2024.132071_bb0010","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.cardfail.2007.12.001","article-title":"Incident heart failure hospitalization and subsequent mortality in chronic heart failure: a propensity-matched study","volume":"14","author":"Ahmed","year":"2008","journal-title":"J. Card. Fail."},{"issue":"36","key":"10.1016\/j.ijcard.2024.132071_bb0015","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1093\/eurheartj\/ehab368","volume":"42","author":"McDonagh","year":"2021","journal-title":"Eur. Heart J."},{"issue":"1","key":"10.1016\/j.ijcard.2024.132071_bb0020","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1373\/clinchem.2011.165720","article-title":"Emerging biomarkers in heart failure","volume":"58","author":"van Kimmenade","year":"2012","journal-title":"Clin. Chem."},{"issue":"4","key":"10.1016\/j.ijcard.2024.132071_bb0025","first-page":"268","article-title":"Soluble urokinase-type plasminogen activator receptor improves risk prediction in patients with chronic heart failure. JACC","volume":"5","author":"Koller","year":"2017","journal-title":"Heart Fail."},{"issue":"3","key":"10.1016\/j.ijcard.2024.132071_bb0030","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.ekir.2017.02.001","article-title":"Cardiovascular disease biomarkers and suPAR in predicting decline in renal function: a prospective cohort study","volume":"2","author":"Hayek","year":"2017","journal-title":"Kidney Intern. Reports."},{"issue":"3\u20134","key":"10.1016\/j.ijcard.2024.132071_bb0035","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1155\/2009\/504294","article-title":"suPAR: the molecular crystal ball","volume":"27","author":"Thun\u00f8","year":"2009","journal-title":"Dis. Markers"},{"issue":"12","key":"10.1016\/j.ijcard.2024.132071_bb0040","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1038\/nrm977","article-title":"uPAR: a versatile signalling orchestrator","volume":"3","author":"Blasi","year":"2002","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"10","key":"10.1016\/j.ijcard.2024.132071_bb0045","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1016\/j.cjca.2015.03.023","article-title":"suPAR: a new biomarker for cardiovascular disease?","volume":"31","author":"Hodges","year":"2015","journal-title":"Can. J. Cardiol."},{"issue":"3","key":"10.1016\/j.ijcard.2024.132071_bb0050","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1080\/1354750X.2022.2038269","article-title":"Soluble urokinase plasminogen activator receptor and functionally relevant coronary artery disease: a prospective cohort study","volume":"27","author":"Walter","year":"2022","journal-title":"Biomarkers"},{"key":"10.1016\/j.ijcard.2024.132071_bb0055","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.atherosclerosis.2017.06.019","article-title":"Circulating soluble urokinase plasminogen activator receptor levels and peripheral arterial disease outcomes","volume":"264","author":"Tahhan","year":"2017","journal-title":"Atherosclerosis"},{"issue":"12","key":"10.1016\/j.ijcard.2024.132071_bb0060","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1016\/j.amjcard.2012.08.008","article-title":"Usefulness of soluble urokinase plasminogen activator receptor to predict repeat myocardial infarction and mortality in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous intervention","volume":"110","author":"Lyngb\u00e6k","year":"2012","journal-title":"Am. J. Cardiol."},{"issue":"2","key":"10.1016\/j.ijcard.2024.132071_bb0065","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.cardfail.2022.08.010","article-title":"Soluble urokinase plasminogen activator receptor levels and outcomes in patients with heart failure","volume":"29","author":"Hayek","year":"2023","journal-title":"J. Card. Fail."},{"issue":"2","key":"10.1016\/j.ijcard.2024.132071_bb0070","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/ejhf.612","article-title":"Superior performance of N-terminal pro brain natriuretic peptide for diagnosis of acute decompensated heart failure in an Asian compared with a Western setting","volume":"19","author":"Ibrahim","year":"2017","journal-title":"Eur. J. Heart Fail."},{"issue":"4","key":"10.1016\/j.ijcard.2024.132071_bb0075","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1002\/ejhf.1660","article-title":"Mid-regional pro-adrenomedullin outperforms N-terminal pro-B-type natriuretic peptide for the diagnosis of acute heart failure in the presence of atrial fibrillation","volume":"22","author":"Kuan","year":"2020","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcard.2024.132071_bb0080","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.clinbiochem.2019.05.010","article-title":"Analytical, biochemical and clearance considerations of soluble urokinase plasminogen activator receptor (suPAR) in healthy individuals","volume":"69","author":"Chew-Harris","year":"2019","journal-title":"Clin. Biochem."},{"issue":"22","key":"10.1016\/j.ijcard.2024.132071_bb0085","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1016\/j.jacc.2016.09.931","article-title":"Prognostic implications of changes in N-terminal pro-B-type natriuretic peptide in patients with heart failure","volume":"68","author":"Zile","year":"2016","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2024.132071_bb0090","doi-asserted-by":"crossref","unstructured":"Pocock SJ, Ariti CA, McMurray JJ, et al. Predicting survival in heart failure: a risk score based on 39 372 patients from 30 studies. Eur. Heart J. 34(19):1404\u201313.","DOI":"10.1093\/eurheartj\/ehs337"},{"issue":"6","key":"10.1016\/j.ijcard.2024.132071_bb0095","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1080\/14017431.2020.1762917","article-title":"SuPAR is associated with death and adverse cardiovascular outcomes in patients with suspected coronary artery disease","volume":"54","author":"Hodges","year":"2020","journal-title":"Scand. Cardiovasc. J."},{"issue":"11","key":"10.1016\/j.ijcard.2024.132071_bb0100","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1373\/clinchem.2013.203778","article-title":"Soluble urokinase plasminogen activator receptor for risk prediction in patients admitted with acute chest pain","volume":"59","author":"Lyngb\u00e6k","year":"2013","journal-title":"Clin. Chem."},{"issue":"1","key":"10.1016\/j.ijcard.2024.132071_bb0105","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.atherosclerosis.2011.01.049","article-title":"Soluble urokinase plasminogen activator receptor is associated with subclinical organ damage and cardiovascular events","volume":"216","author":"Sehestedt","year":"2011","journal-title":"Atherosclerosis"},{"issue":"24","key":"10.1016\/j.ijcard.2024.132071_bb0110","doi-asserted-by":"crossref","DOI":"10.1172\/JCI158788","article-title":"Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis","volume":"132","author":"Hindy","year":"2022","journal-title":"J. Clin. Invest."},{"issue":"4","key":"10.1016\/j.ijcard.2024.132071_bb0115","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1002\/ejhf.49","article-title":"Increased plasma level of soluble urokinase plasminogen activator receptor is associated with incidence of heart failure but not atrial fibrillation","volume":"16","author":"Born\u00e9","year":"2014","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcard.2024.132071_bb0120","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1007\/s00380-017-1002-7","article-title":"Association between suPAR and cardiac diastolic dysfunction among patients with preserved ejection fraction","volume":"32","author":"Fujisaka","year":"2017","journal-title":"Heart Vessel."},{"issue":"1","key":"10.1016\/j.ijcard.2024.132071_bb0125","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0170546","article-title":"Serum soluble urokinase-type plasminogen activator receptor is associated with low left ventricular ejection fraction and elevated plasma brain-type natriuretic peptide level","volume":"12","author":"Fujita","year":"2017","journal-title":"PLoS One"},{"issue":"20","key":"10.1016\/j.ijcard.2024.132071_bb0130","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1056\/NEJMoa1506362","article-title":"Soluble urokinase receptor and chronic kidney disease","volume":"373","author":"Hayek","year":"2015","journal-title":"N. Engl. J. Med."},{"issue":"8","key":"10.1016\/j.ijcard.2024.132071_bb0135","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1038\/nm.2411","article-title":"Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis","volume":"17","author":"Wei","year":"2011","journal-title":"Nat. Med."},{"issue":"29","key":"10.1016\/j.ijcard.2024.132071_bb0140","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1093\/eurheartj\/ehu207","article-title":"Towards better clinical prediction models: seven steps for development and an ABCD for validation","volume":"35","author":"Steyerberg","year":"2014","journal-title":"Eur. Heart J."},{"issue":"7","key":"10.1016\/j.ijcard.2024.132071_bb0145","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1515\/cclm-2020-0903","article-title":"Long term prognostic value of suPAR in chronic heart failure: reclassification of patients with low MAGGIC score","volume":"59","author":"Dupuy","year":"2021","journal-title":"Clin. Chem. Lab. Med. (CCLM)."},{"issue":"10","key":"10.1016\/j.ijcard.2024.132071_bb0150","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1038\/s41591-021-01499-z","article-title":"Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial","volume":"27","author":"Kyriazopoulou","year":"2021","journal-title":"Nat. Med."}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527324006910?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527324006910?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T05:41:42Z","timestamp":1715060502000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527324006910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":30,"alternative-id":["S0167527324006910"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2024.132071","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prognostic performance of soluble urokinase plasminogen activator receptor for heart failure or mortality in Western and Asian patients with acute breathlessness","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2024.132071","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"132071"}}