{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T08:08:36Z","timestamp":1787731716312,"version":"build-2784847793"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82003561"],"award-info":[{"award-number":["82003561"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.ijcard.2025.133218","type":"journal-article","created":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T02:08:17Z","timestamp":1743300497000},"page":"133218","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Distinct lipoprotein contributions to valvular heart disease: Insights from genetic analysis"],"prefix":"10.1016","volume":"431","author":[{"given":"Da","family":"Luo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elias","family":"Bj\u00f6rnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bofang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changwu","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunlong","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shizhen","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Bor\u00e9n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingjie","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcard.2025.133218_bb0005","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1136\/heartjnl-2014-307020","article-title":"The modern epidemiology of heart valve disease","volume":"102","author":"Coffey","year":"2016","journal-title":"Heart"},{"key":"10.1016\/j.ijcard.2025.133218_bb0010","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1093\/eurheartj\/ehad121","article-title":"Unmet needs in valvular heart disease","volume":"44","author":"Messika-Zeitoun","year":"2023","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133218_bb0015","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0140-6736(06)69208-8","article-title":"Burden of valvular heart diseases: a population-based study","volume":"368","author":"Nkomo","year":"2006","journal-title":"Lancet Lond. Engl."},{"key":"10.1016\/j.ijcard.2025.133218_bb0020","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1146\/annurev-med-042921-122533","article-title":"Valvular heart disease: new concepts in pathophysiology and therapeutic approaches","volume":"74","author":"Eleid","year":"2023","journal-title":"Annu. Rev. Med."},{"key":"10.1016\/j.ijcard.2025.133218_bb0025","article-title":"2020 ACC\/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association joint committee on clinical practice guidelines","author":"Otto","year":"2021","journal-title":"Circulation"},{"issue":"2022","key":"10.1016\/j.ijcard.2025.133218_bb0030","first-page":"561","article-title":"ESC\/EACTS guidelines for the management of valvular heart disease","volume":"43","author":"Vahanian","year":"2021","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133218_bb0035","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1038\/s41569-023-00845-7","article-title":"Calcific aortic valve disease: mechanisms, prevention and treatment","volume":"20","author":"Moncla","year":"2023","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133218_bb0040","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1093\/eurheartj\/ehab757","article-title":"Calcific aortic valve disease: from molecular and cellular mechanisms to medical therapy","volume":"43","author":"Kraler","year":"2022","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133218_bb0045","doi-asserted-by":"crossref","first-page":"3913","DOI":"10.1093\/eurheartj\/ehaa070","article-title":"Plasma lipids and risk of aortic valve stenosis: a Mendelian randomization study","volume":"41","author":"Nazarzadeh","year":"2020","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133218_bb0050","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1056\/NEJMoa1109034","article-title":"CHARGE Extracoronary calcium working group, genetic associations with valvular calcification and aortic stenosis","volume":"368","author":"Thanassoulis","year":"2013","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijcard.2025.133218_bb0055","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1093\/eurheartj\/ehad142","article-title":"Thanassoulis, dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study","volume":"44","author":"Yu Chen","year":"2023","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133218_bb0060","doi-asserted-by":"crossref","first-page":"2389","DOI":"10.1056\/NEJMoa043876","article-title":"Scottish aortic stenosis and lipid lowering trial, impact on regression (SALTIRE) Investigators, a randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis","volume":"352","author":"Cowell","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijcard.2025.133218_bb0065","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1161\/CIRCULATIONAHA.109.900027","article-title":"ASTRONOMER Investigators, effect of lipid lowering with rosuvastatin on progression of aortic stenosis: results of the aortic stenosis progression observation: measuring effects of rosuvastatin (ASTRONOMER) trial","volume":"121","author":"Chan","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2025.133218_bb0070","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1056\/NEJMoa0804602","article-title":"Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis","volume":"359","author":"Rosseb\u00f8","year":"2008","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijcard.2025.133218_bb0075","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1161\/CIRCULATIONAHA.123.067537","article-title":"Atorvastatin effect on aortic dilatation and valvular calcification progression in bicuspid aortic valve (BICATOR): a randomized clinical trial","volume":"149","author":"Evangelista","year":"2024","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2025.133218_bb0080","doi-asserted-by":"crossref","first-page":"4186","DOI":"10.1093\/eurheartj\/ehad337","article-title":"Triglyceride-rich lipoprotein remnants, low-density lipoproteins, and risk of coronary heart disease: a UK biobank study","volume":"44","author":"Bj\u00f6rnson","year":"2023","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133218_bb0085","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.jacc.2023.10.039","article-title":"Lipoprotein(a) is markedly more atherogenic than LDL","volume":"83","author":"Bj\u00f6rnson","year":"2024","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133218_bb0090","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1016\/j.jacc.2020.09.610","article-title":"VLDL cholesterol accounts for one-half of the risk of myocardial infarction associated with apoB-containing lipoproteins","volume":"76","author":"Balling","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133218_bb0095","doi-asserted-by":"crossref","first-page":"4791","DOI":"10.1093\/eurheartj\/ehab551","article-title":"Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies-a consensus statement from the European atherosclerosis society","volume":"42","author":"Ginsberg","year":"2021","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133218_bb0100","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001779","article-title":"UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age","volume":"12","author":"Sudlow","year":"2015","journal-title":"PLoS Med."},{"key":"10.1016\/j.ijcard.2025.133218_bb0105","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/s41586-022-05473-8","article-title":"FinnGen provides genetic insights from a well-phenotyped isolated population","volume":"613","author":"Kurki","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.ijcard.2025.133218_bb0110","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s13059-020-02248-0","article-title":"The variant call format provides efficient and robust storage of GWAS summary statistics","volume":"22","author":"Lyon","year":"2021","journal-title":"Genome Biol."},{"key":"10.1016\/j.ijcard.2025.133218_bb0115","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1038\/s41467-023-36231-7","article-title":"Atlas of plasma NMR biomarkers for health and disease in 118,461 individuals from the UK biobank","volume":"14","author":"Julkunen","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ijcard.2025.133218_bb0120","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1093\/ije\/dyx028","article-title":"Two-sample Mendelian randomization: avoiding the downsides of a powerful, widely applicable but potentially fallible technique","volume":"45","author":"Hartwig","year":"2016","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.ijcard.2025.133218_bb0125","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-019-14156-4","article-title":"A robust and efficient method for Mendelian randomization with hundreds of genetic variants","volume":"11","author":"Burgess","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ijcard.2025.133218_bb0130","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1093\/aje\/kwu283","article-title":"Multivariable Mendelian randomization: the use of pleiotropic genetic variants to estimate causal effects","volume":"181","author":"Burgess","year":"2015","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.ijcard.2025.133218_bb0135","doi-asserted-by":"crossref","first-page":"5434","DOI":"10.1002\/sim.9133","article-title":"Testing and correcting for weak and pleiotropic instruments in two-sample multivariable Mendelian randomization","volume":"40","author":"Sanderson","year":"2021","journal-title":"Stat. Med."},{"key":"10.1016\/j.ijcard.2025.133218_bb0140","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/gepi.21965","article-title":"Consistent estimation in Mendelian randomization with some invalid instruments using a weighted median estimator","volume":"40","author":"Bowden","year":"2016","journal-title":"Genet. Epidemiol."},{"key":"10.1016\/j.ijcard.2025.133218_bb0145","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1093\/ije\/dyv080","article-title":"Mendelian randomization with invalid instruments: effect estimation and bias detection through egger regression","volume":"44","author":"Bowden","year":"2015","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.ijcard.2025.133218_bb0150","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1038\/s41569-018-0153-2","article-title":"Oxidized phospholipids as a unifying theory for lipoprotein(a) and cardiovascular disease","volume":"16","author":"Boffa","year":"2019","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133218_bb0155","doi-asserted-by":"crossref","first-page":"3925","DOI":"10.1093\/eurheartj\/ehac361","article-title":"Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European atherosclerosis society consensus statement","volume":"43","author":"Kronenberg","year":"2022","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133218_bb0160","doi-asserted-by":"crossref","first-page":"3960","DOI":"10.1093\/eurheartj\/ehac377","article-title":"Lipoprotein(a) is associated with the onset but not the progression of aortic valve calcification","volume":"43","author":"Kaiser","year":"2022","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133218_bb0165","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1093\/eurheartj\/ehad055","article-title":"Lipoprotein(a) is linked to atherothrombosis and aortic valve stenosis independent of C-reactive protein","volume":"44","author":"Thomas","year":"2023","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133218_bb0170","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1016\/j.jacc.2019.01.070","article-title":"Lipoprotein(a) and oxidized phospholipids promote valve calcification in patients with aortic stenosis","volume":"73","author":"Zheng","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133218_bb0175","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1161\/CIRCRESAHA.123.323284","article-title":"VLDL biogenesis and secretion: it takes a village","volume":"134","author":"van Zwol","year":"2024","journal-title":"Circ. Res."},{"key":"10.1016\/j.ijcard.2025.133218_bb0180","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1093\/eurheartj\/ehz962","article-title":"Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European atherosclerosis society consensus panel","volume":"41","author":"Bor\u00e9n","year":"2020","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133218_bb0185","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.1194\/jlr.M800174-JLR200","article-title":"A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma","volume":"49","author":"Bergmark","year":"2008","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.ijcard.2025.133218_bb0190","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/joim.13017","article-title":"Apolipoprotein B48 metabolism in chylomicrons and very low-density lipoproteins and its role in triglyceride transport in normo- and hypertriglyceridemic human subjects","volume":"288","author":"Bj\u00f6rnson","year":"2020","journal-title":"J. Intern. Med."},{"key":"10.1016\/j.ijcard.2025.133218_bb0195","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0021-9150(91)90050-D","article-title":"Effect of moderate hypertriglyceridemia on the relation of plasma total and LDL apo B levels","volume":"89","author":"Sniderman","year":"1991","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.ijcard.2025.133218_bb0200","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1161\/ATVBAHA.107.160192","article-title":"Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome","volume":"28","author":"Adiels","year":"2008","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.ijcard.2025.133218_bb0205","doi-asserted-by":"crossref","first-page":"508","DOI":"10.2337\/dbi19-0007","article-title":"Remnants of the triglyceride-Rich lipoproteins, diabetes, and cardiovascular disease","volume":"69","author":"Chait","year":"2020","journal-title":"Diabetes"},{"key":"10.1016\/j.ijcard.2025.133218_bb0210","doi-asserted-by":"crossref","first-page":"252","DOI":"10.3389\/fendo.2020.00252","article-title":"Causes and consequences of hypertriglyceridemia","volume":"11","author":"Packard","year":"2020","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.ijcard.2025.133218_bb0215","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1093\/eurjpc\/zwaa063","article-title":"Lipoprotein(a) and cardiovascular disease: prediction, attributable risk fraction, and estimating benefits from novel interventions","volume":"28","author":"Welsh","year":"2022","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133218_bb0220","doi-asserted-by":"crossref","DOI":"10.1161\/CIR.0000000000001254","article-title":"Unraveling the mechanisms of valvular heart disease to identify medical therapy targets: a scientific statement from the American Heart Association","author":"Small","year":"2024","journal-title":"Circulation"},{"key":"10.1016\/j.ijcard.2025.133218_bb0225","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1093\/eurheartj\/ehz310","article-title":"Statin therapy increases lipoprotein(a) levels","volume":"41","author":"Tsimikas","year":"2020","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133218_bb0230","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1016\/j.jacc.2009.10.053","article-title":"Atorvastatin causes insulin resistance and increases ambient glycemia in hypercholesterolemic patients","volume":"55","author":"Koh","year":"2010","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133218_bb0235","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1056\/NEJMoa2211023","article-title":"OCEAN(a)-DOSE trial investigators, small interfering RNA to reduce lipoprotein(a) in cardiovascular disease","volume":"387","author":"O\u2019Donoghue","year":"2022","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijcard.2025.133218_bb0240","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1056\/NEJMoa1905239","article-title":"AKCEA-APO(a)-LRx study Investigators, lipoprotein(a) reduction in persons with cardiovascular disease","volume":"382","author":"Tsimikas","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijcard.2025.133218_bb0245","doi-asserted-by":"crossref","first-page":"2941","DOI":"10.1016\/j.jacc.2017.04.051","article-title":"CHARGE extracoronary calcium working group, association of triglyceride-related genetic variants with mitral annular calcification","volume":"69","author":"Afshar","year":"2017","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133218_bb0250","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1001\/jamacardio.2019.2202","article-title":"Systolic blood pressure and risk of Valvular heart disease: a Mendelian randomization study","volume":"4","author":"Nazarzadeh","year":"2019","journal-title":"JAMA Cardiol."}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016752732500261X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016752732500261X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T10:56:30Z","timestamp":1762253790000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016752732500261X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":50,"alternative-id":["S016752732500261X"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2025.133218","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Distinct lipoprotein contributions to valvular heart disease: Insights from genetic analysis","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2025.133218","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"133218"}}