{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T05:58:48Z","timestamp":1794031128504,"version":"4.8.0"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T00:00:00Z","timestamp":1745280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.ijcard.2025.133290","type":"journal-article","created":{"date-parts":[[2025,4,19]],"date-time":"2025-04-19T11:05:31Z","timestamp":1745060731000},"page":"133290","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["LDL-cholesterol levels and lipid lowering therapy in secondary prevention. Baseline data from the BRING-UP prospective registry"],"prefix":"10.1016","volume":"433","author":[{"given":"Furio","family":"Colivicchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianna","family":"Fabbri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Oliva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio Giuseppe","family":"Abrignani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcello","family":"Arca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Averna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberico Luigi","family":"Catapano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Ceseri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania Angela","family":"Di Fusco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Di Lenarda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Fattirolli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Gabrielli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucio","family":"Gonzini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele Massimo","family":"Gulizia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmine","family":"Riccio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pier Luigi","family":"Temporelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Aloia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Alonzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Aschieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuele","family":"Barbato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Bertoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Calabr\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Cal\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Carugo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Crisci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"La Rosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Maffei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Navazio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Pavan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Scelza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Scicchitano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakis","family":"Themistoclakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aldo Pietro","family":"Maggioni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8478","key":"10.1016\/j.ijcard.2025.133290_bb0005","first-page":"397","volume":"1","year":"1986","journal-title":"Lancet"},{"key":"10.1016\/j.ijcard.2025.133290_bb0010","first-page":"441","article-title":"Contemporary antithrombotic strategies in patients with acute coronary syndromes admitted to cardiac care units in Italy: the EYESHOT study","volume":"4","author":"De Luca","year":"2015","journal-title":"Eur. Heart J. Acute Cardiovasc. Care"},{"issue":"6","key":"10.1016\/j.ijcard.2025.133290_bb0015","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.120.008962","article-title":"Management of percutaneous coronary intervention complications: algorithms from the 2018 and 2019 seattle percutaneous coronary intervention complications conference","volume":"13","author":"Doll","year":"2020","journal-title":"Circ. Cardiovasc. Interv."},{"key":"10.1016\/j.ijcard.2025.133290_bb0025","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1177\/2047487315569401","article-title":"EUROASPIRE IV: a European Society of Cardiology survey on the lifestyle, risk factor and therapeutic management of coronary patients from 24 European countries","volume":"23","author":"Kotseva","year":"2016","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133290_bb0030","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1177\/2047487318825350","article-title":"Lifestyle and impact on cardiovascular risk factor control in coronary patients across 27 countries: results from the European Society of Cardiology ESC-EORP EUROASPIRE V registry","volume":"26","author":"Kotseva","year":"2019","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133290_bb0035","doi-asserted-by":"crossref","first-page":"3227","DOI":"10.1093\/eurheartj\/ehab484","article-title":"2021 ESC Guidelines on cardiovascular disease prevention in clinical practice","volume":"42","author":"Visseren","year":"2021","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133290_bb0040","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/eurheartj\/ehz425","article-title":"2019 ESC guidelines for the diagnosis and management of chronic coronary syndromes","volume":"41","author":"Knuuti","year":"2020","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133290_bb0045","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/eurheartj\/ehz455","article-title":"2019 ESC\/EAS guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk","volume":"41","author":"Mach","year":"2020","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133290_bb0070","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1093\/eurheartj\/ehz486","article-title":"2019 ESC guidelines on diabetes, pre diabetes, and cardiovascular diseases developed in collaboration with the EASD","volume":"41","author":"Cosentino","year":"2020","journal-title":"Eur. Heart J."},{"issue":"20","key":"10.1016\/j.ijcard.2025.133290_bb0020","doi-asserted-by":"crossref","first-page":"4708","DOI":"10.3390\/jcm10204708","article-title":"Coronary artery disease in patients older than 35 and eligible for cardiovascular secondary prevention: an Italian retrospective observational analysis of healthcare administrative databases","volume":"10","author":"Calabria","year":"2021","journal-title":"J. Clin. Med."},{"issue":"16","key":"10.1016\/j.ijcard.2025.133290_bb0050","doi-asserted-by":"crossref","first-page":"4888","DOI":"10.3390\/jcm11164888","article-title":"Antiplatelet therapy during the first year after acute coronary syndrome in a contemporary Italian Community of over 5 million subjects","volume":"11","author":"Calabria","year":"2022","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.ijcard.2025.133290_bb0055","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.ijcard.2017.02.108","article-title":"Use of lipid lowering drugs in patients at very high risk of cardiovascular events: an analysis on nearly 3,000,000 Italian subjects of the ARNO observatory","volume":"246","author":"Maggioni","year":"2017","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133290_bb0060","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.atherosclerosis.2020.07.007","article-title":"Prevalence of familial hypercholeSTerolaemia (FH) in Italian patients with coronary artERy disease: the POSTER study","volume":"308","author":"Gulizia","year":"2020","journal-title":"Atherosclerosis"},{"issue":"6 Suppl 1","key":"10.1016\/j.ijcard.2025.133290_bb0065","first-page":"3S","article-title":"ANMCO\/ISS\/AMD\/ANCE\/ARCA\/FADOI\/GICR-IACPR\/SICI-GISE\/SIBioC\/SIC\/SICOA\/SID\/SIF\/SIMEU\/SIMG\/SIMI\/SISA Consensus document. Hypercholesterolemia and cardiovascular risk: diagnostic and therapeutic pathways in Italy","volume":"17","author":"Gulizia","year":"2016","journal-title":"G. Ital. Cardiol. (Rome)"},{"key":"10.1016\/j.ijcard.2025.133290_bb0085","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1136\/heart.89.3.299","article-title":"Treatment of chronic heart failure with beta adrenergic blockade beyond controlled clinical trials: the BRING-UP experience","volume":"89","author":"Maggioni","year":"2003","journal-title":"Heart"},{"key":"10.1016\/j.ijcard.2025.133290_bb0090","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.ejheart.2005.11.005","article-title":"Programme to improve the use of beta-blockers for heart failure in the elderly and in those with severe symptoms: results of the BRING-UP 2 study","volume":"8","author":"Opasich","year":"2006","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcard.2025.133290_bb0095","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1002\/ejhf.2605","article-title":"BLITZ HF: a nationwide initiative to evaluate and improve adherence to acute and chronic heart failure guidelines","volume":"24","author":"Gulizia","year":"2022","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcard.2025.133290_bb0100","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1093\/eurheartj\/ehac074","article-title":"A training project to promote clinical research among young cardiologists","volume":"43","author":"Di Fusco","year":"2022","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcard.2025.133290_bb0105","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1093\/eurjpc\/zwaa047","article-title":"EU-wide cross-sectional observational study of lipid-modifying therapy use in secondary and primary care: the DA VINCI study","volume":"28","author":"Ray","year":"2021","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133290_bb0110","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1177\/1741826711400545","article-title":"Persistent lipid abnormalities in statin-treated patients and predictors of LDL-cholesterol goal achievement in clinical practice in Europe and Canada","volume":"19","author":"Gitt","year":"2012","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133290_bb0115","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1177\/2047487312444995","article-title":"Secondary prevention and risk factor target achievement in a global, high-risk population with established coronary heart disease: baseline results from the STABILITY study","volume":"20","author":"Vedin","year":"2013","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133290_bb0120","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1177\/2047487314547652","article-title":"Geographical variations in the prevalence and management of cardiovascular risk factors in outpatients with CAD: data from the contemporary CLARIFY registry","volume":"22","author":"Ferrari","year":"2015","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133290_bb0125","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1001\/jama.290.1.86","article-title":"Mortality risk reduction associated with smoking cessation in patients with coronary heart disease: a systematic review","volume":"290","author":"Critchley","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.ijcard.2025.133290_bb0130","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.jacc.2017.05.041","article-title":"Community-based lifestyle intervention in patients with coronary artery disease: the RESPONSE-2 trial","volume":"70","author":"Minneboo","year":"2017","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133290_bb0135","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1177\/2047487317711334","article-title":"Psychosocial risk factors in relation to other cardiovascular risk factors in coronary heart disease: results from the EUROASPIRE IV survey. A registry from the European Society of Cardiology","volume":"24","author":"Pogosova","year":"2017","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.ijcard.2025.133290_bb0140","doi-asserted-by":"crossref","first-page":"3213","DOI":"10.1093\/eurheartj\/ehac015","article-title":"Prevalence of statin intolerance: a meta-analysis","volume":"43","author":"Byty\u00e7i","year":"2022","journal-title":"Eur. Heart J."}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016752732500333X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016752732500333X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T10:57:47Z","timestamp":1758193067000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016752732500333X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":26,"alternative-id":["S016752732500333X"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2025.133290","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"LDL-cholesterol levels and lipid lowering therapy in secondary prevention. Baseline data from the BRING-UP prospective registry","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2025.133290","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"133290"}}