{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T15:35:32Z","timestamp":1793028932562,"version":"4.5.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100006095","name":"South-Eastern Norway Regional Health Authority","doi-asserted-by":"publisher","award":["2018105"],"award-info":[{"award-number":["2018105"]}],"id":[{"id":"10.13039\/501100006095","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012446","name":"Akershus Universitetssykehus","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012446","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005366","name":"Universitetet i Oslo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005366","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.ijcard.2026.134991","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:55:02Z","timestamp":1791906902000},"page":"134991","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Prognostic associations of left atrial strain with major adverse cardiovascular events and atrial fibrillation: Data from the Akershus Cardiac Examination (ACE) 1950 Study"],"prefix":"10.1016","volume":"465","author":[{"given":"Magnar G.","family":"Solberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter S.","family":"R\u00f8nningen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trygve","family":"Berge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve","family":"Enger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Osman","family":"Pervez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eivind B.","family":"Orstad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brede","family":"Kvisvik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika N.","family":"Aagaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus N.","family":"Lyngbakken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torbj\u00f8rn","family":"Omland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helge","family":"R\u00f8sj\u00f8","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kjetil","family":"Steine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnljot","family":"Tveit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10258","key":"10.1016\/j.ijcard.2026.134991_bb0005","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1016\/S0140-6736(20)30752-2","article-title":"Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the global burden of disease study 2019","volume":"396","author":"Murray","year":"2020","journal-title":"Lancet"},{"issue":"36","key":"10.1016\/j.ijcard.2026.134991_bb0010","doi-asserted-by":"crossref","first-page":"3314","DOI":"10.1093\/eurheartj\/ehae176","article-title":"2024 ESC guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"45","author":"Van Gelder","year":"2024","journal-title":"Eur. Heart J."},{"issue":"9","key":"10.1016\/j.ijcard.2026.134991_bb0015","doi-asserted-by":"crossref","DOI":"10.1093\/europace\/euae204","volume":"26","author":"Goette","year":"2024","journal-title":"Europace"},{"issue":"9","key":"10.1016\/j.ijcard.2026.134991_bb0020","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1093\/ehjci\/jeaf206","article-title":"Left atrial strain in heart failure with reduced ejection fraction: from emerging evidence to clinical integration","volume":"26","author":"Donal","year":"2025","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"issue":"1","key":"10.1016\/j.ijcard.2026.134991_bb0025","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/ehjci\/jeaa415","article-title":"Determinants of left atrial reservoir and pump strain and use of atrial strain for evaluation of left ventricular filling pressure","volume":"23","author":"Inoue","year":"2021","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"issue":"1","key":"10.1016\/j.ijcard.2026.134991_bb0030","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1093\/ehjci\/jeab191","article-title":"Imaging of the left atrium: pathophysiology insights and clinical utility","volume":"23","author":"Smiseth","year":"2021","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"issue":"7","key":"10.1016\/j.ijcard.2026.134991_bb0035","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1093\/ehjci\/jey181","article-title":"Prognostic value of left atrial strain in predicting cardiovascular morbidity and mortality in the general population","volume":"20","author":"Modin","year":"2019","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"10.1016\/j.ijcard.2026.134991_bb0040","doi-asserted-by":"crossref","DOI":"10.1007\/s00392-025-02787-1","article-title":"Three-dimensional left atrial strain is associated with heart failure and cardiovascular death in the general population","author":"Yafasov","year":"2025","journal-title":"Clin. Res. Cardiol."},{"issue":"3","key":"10.1016\/j.ijcard.2026.134991_bb0045","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1161\/CIRCIMAGING.109.865683","article-title":"Left atrial strain and strain rate in patients with paroxysmal and persistent atrial fibrillation: relationship to left atrial structural remodeling detected by delayed-enhancement MRI","volume":"3","author":"Kuppahally","year":"2010","journal-title":"Circ. Cardiovasc. Imaging"},{"issue":"11","key":"10.1016\/j.ijcard.2026.134991_bb0050","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1016\/j.jcmg.2017.07.027","article-title":"Use of atrial strain to predict atrial fibrillation after cerebral ischemia","volume":"11","author":"Pathan","year":"2018","journal-title":"J. Am. Coll. Cardiol. Img."},{"key":"10.1016\/j.ijcard.2026.134991_bb0055","doi-asserted-by":"crossref","DOI":"10.1093\/ehjci\/jeab202","article-title":"Left atrial strain predicts incident atrial fibrillation in the general population: the Copenhagen City heart study","author":"Hauser","year":"2021","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"issue":"10","key":"10.1016\/j.ijcard.2026.134991_bb0060","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1016\/j.echo.2019.06.002","article-title":"Left atrial mechanical dispersion assessed by strain echocardiography as an independent predictor of new-onset atrial fibrillation: a case-control study","volume":"32","author":"Kawakami","year":"2019","journal-title":"J. Am. Soc. Echocardiogr."},{"issue":"1","key":"10.1016\/j.ijcard.2026.134991_bb0065","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s10741-015-9520-9","article-title":"Left atrial strain: a new parameter for assessment of left ventricular filling pressure","volume":"21","author":"Cameli","year":"2016","journal-title":"Heart Fail. Rev."},{"issue":"7","key":"10.1016\/j.ijcard.2026.134991_bb0070","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1002\/ejhf.1464","article-title":"Left atrial strain and compliance in the diagnostic evaluation of heart failure with preserved ejection fraction","volume":"21","author":"Reddy","year":"2019","journal-title":"Eur. J. Heart Fail."},{"issue":"1","key":"10.1016\/j.ijcard.2026.134991_bb0075","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1161\/CIRCIMAGING.108.813071","article-title":"Left atrial function in diastolic heart failure","volume":"2","author":"Kurt","year":"2009","journal-title":"Circ. Cardiovasc. Imaging"},{"issue":"4","key":"10.1016\/j.ijcard.2026.134991_bb0080","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.jcmg.2022.11.002","article-title":"Prognostic implications of left atrial stiffness index in heart failure patients with preserved ejection fraction","volume":"16","author":"Kim","year":"2023","journal-title":"JACC Cardiovasc. Imaging"},{"issue":"5","key":"10.1016\/j.ijcard.2026.134991_bb0085","doi-asserted-by":"crossref","DOI":"10.3390\/jcm9051244","article-title":"Speckle tracking-derived left atrial stiffness predicts clinical outcome in heart failure patients with reduced to mid-range ejection fraction","volume":"9","author":"Bytyci","year":"2020","journal-title":"J. Clin. Med."},{"issue":"2","key":"10.1016\/j.ijcard.2026.134991_bb0090","first-page":"183","article-title":"Left ventricular mechanical dispersion in a general population: data from the Akershus cardiac examination 1950 study","volume":"21","author":"Aagaard","year":"2020","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"issue":"6","key":"10.1016\/j.ijcard.2026.134991_bb0095","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1093\/ehjci\/jey042","article-title":"Standardization of left atrial, right ventricular, and right atrial deformation imaging using two-dimensional speckle tracking echocardiography: a consensus document of the EACVI\/ASE\/industry task force to standardize deformation imaging","volume":"19","author":"Badano","year":"2018","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"issue":"FI_3","key":"10.1016\/j.ijcard.2026.134991_bb0100","doi-asserted-by":"crossref","first-page":"f299","DOI":"10.1093\/europace\/eux293","article-title":"Systematic screening for atrial fibrillation in a 65-year-old population with risk factors for stroke: data from the Akershus cardiac examination 1950 study","volume":"20","author":"Berge","year":"2018","journal-title":"Europace"},{"issue":"2","key":"10.1016\/j.ijcard.2026.134991_bb0105","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.112.000102","article-title":"Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium","volume":"2","author":"Alonso","year":"2013","journal-title":"J. Am. Heart Assoc."},{"issue":"6","key":"10.1016\/j.ijcard.2026.134991_bb0110","doi-asserted-by":"crossref","DOI":"10.1111\/echo.15852","article-title":"Left atrial function in middle-aged men and women with and without paroxysmal atrial fibrillation: data from the Akershus cardiac examination (ACE) 1950 study","volume":"41","author":"Solberg","year":"2024","journal-title":"Echocardiography"},{"issue":"3","key":"10.1016\/j.ijcard.2026.134991_bb0115","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/s41440-020-00551-8","article-title":"Left atrial stiffness index as a marker of early target organ damage in hypertension","volume":"44","author":"Zhao","year":"2021","journal-title":"Hypertens. Res."},{"issue":"4","key":"10.1016\/j.ijcard.2026.134991_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.jacadv.2024.100903","article-title":"Association of Left Atrial Stiffness with Risk of cryptogenic ischemic stroke in young adults","volume":"3","author":"Sindre","year":"2024","journal-title":"JACC Adv."},{"key":"10.1016\/j.ijcard.2026.134991_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijcard.2025.133087","article-title":"Prognostic implications of the left atrial stiffness index in patients with cardiac amyloidosis","volume":"426","author":"Gao","year":"2025","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcard.2026.134991_bb0130","doi-asserted-by":"crossref","DOI":"10.1007\/s10554-020-02154-3","article-title":"The prognostic value of left atrial dyssynchrony measured by speckle tracking echocardiography in the general population","author":"Karsum","year":"2021","journal-title":"Int. J. Cardiovasc. Imaging"},{"issue":"9","key":"10.1016\/j.ijcard.2026.134991_bb0135","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1093\/ehjci\/jeaf205","article-title":"Measures of left atrial function and risk of incident atrial fibrillation in patients with heart failure with reduced ejection fraction","volume":"26","author":"Stanchev","year":"2025","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"10.1016\/j.ijcard.2026.134991_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijcard.2024.132544","article-title":"Left atrial strain measured by three-dimensional echocardiography predicts atrial fibrillation in the general population","volume":"417","author":"Yafasov","year":"2024","journal-title":"Int. J. Cardiol."},{"issue":"12","key":"10.1016\/j.ijcard.2026.134991_bb0145","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1093\/ehjci\/jeae162","article-title":"Cardiac mechanics and the risk of atrial fibrillation in a community-based cohort of older adults","volume":"25","author":"Inciardi","year":"2024","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"issue":"5","key":"10.1016\/j.ijcard.2026.134991_bb0150","doi-asserted-by":"crossref","first-page":"311","DOI":"10.4070\/kcj.2012.42.5.311","article-title":"Prediction of left atrial fibrosis with speckle tracking echocardiography in mitral valve disease: a comparative study with histopathology","volume":"42","author":"Her","year":"2012","journal-title":"Korean Circ. J."},{"key":"10.1016\/j.ijcard.2026.134991_bb0155","doi-asserted-by":"crossref","first-page":"185","DOI":"10.2147\/CLEP.S103346","article-title":"Validation of self-reported and hospital-diagnosed atrial fibrillation: the HUNT study","volume":"8","author":"Malmo","year":"2016","journal-title":"Clin. Epidemiol."},{"issue":"3","key":"10.1016\/j.ijcard.2026.134991_bb0160","doi-asserted-by":"crossref","DOI":"10.1093\/europace\/euaf019","article-title":"Atrial fibrillation burden in clinical practice, research, and technology development: a clinical consensus statement of the European Society of Cardiology Council on stroke and the European heart rhythm association","volume":"27","author":"Doehner","year":"2025","journal-title":"Europace"},{"issue":"2","key":"10.1016\/j.ijcard.2026.134991_bb0165","doi-asserted-by":"crossref","first-page":"190","DOI":"10.23736\/S2724-5683.23.06446-3","article-title":"Modified Haller index is inversely associated with asymptomatic status in atrial fibrillation patients undergoing electrical cardioversion: a preliminary observation","volume":"72","author":"Sonaglioni","year":"2024","journal-title":"Minerva Cardiol. Angiol."}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527326008417?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527326008417?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T14:56:15Z","timestamp":1793026575000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527326008417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":33,"alternative-id":["S0167527326008417"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2026.134991","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prognostic associations of left atrial strain with major adverse cardiovascular events and atrial fibrillation: Data from the Akershus Cardiac Examination (ACE) 1950 Study","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2026.134991","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"134991"}}