{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T18:33:56Z","timestamp":1793212436517,"version":"4.5.0"},"reference-count":8,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","internationaljournalofcardiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Cardiology"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.ijcard.2026.135004","type":"journal-article","created":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T14:54:25Z","timestamp":1792508065000},"page":"135004","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Reversible wall motion abnormalities do not predict long-term mortality if coronary flow reserve is accounted for: A 15-year contrast stress-echo study"],"prefix":"10.1016","volume":"466","author":[{"given":"Nicola","family":"Gaibazzi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giampaolo","family":"Niccoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Sartorio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Tuttolomondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.ijcard.2026.135004_bb0005","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1016\/j.amjcard.2016.01.002","article-title":"Long-term (>10 years) prognostic value of dobutamine stress echocardiography in a high-risk cohort","volume":"117","author":"van der Sijde","year":"2016","journal-title":"Am. J. Cardiol."},{"issue":"5","key":"10.1016\/j.ijcard.2026.135004_bb0010","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.echo.2020.01.007","article-title":"Coronary flow velocity reserve reduction is associated with cardiovascular, cancer, and noncancer, Noncardiovascular Mortality","volume":"33","author":"Gaibazzi","year":"2020","journal-title":"J. Am. Soc. Echocardiogr."},{"issue":"1","key":"10.1016\/j.ijcard.2026.135004_bb0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.echo.2019.07.001","article-title":"Guidelines for performance, interpretation, and application of stress echocardiography in ischemic heart disease: from the American Society of Echocardiography","volume":"33","author":"Pellikka","year":"2020","journal-title":"J. Am. Soc. Echocardiogr."},{"issue":"1","key":"10.1016\/j.ijcard.2026.135004_bb0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jcmg.2012.08.009","article-title":"Comparative prediction of cardiac events by wall motion, wall motion plus coronary flow reserve, or myocardial perfusion analysis: a multicenter study of contrast stress echocardiography","volume":"6","author":"Gaibazzi","year":"2013","journal-title":"JACC Cardiovasc. Imaging"},{"issue":"16","key":"10.1016\/j.ijcard.2026.135004_bb0025","doi-asserted-by":"crossref","DOI":"10.3390\/jcm10163641","article-title":"Stress echo 2030: the novel ABCDE-(FGLPR) protocol to define the future of imaging","volume":"10","author":"Picano","year":"2021","journal-title":"J. Clin. Med."},{"issue":"3","key":"10.1016\/j.ijcard.2026.135004_bb0030","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/S0735-1097(99)00250-8","article-title":"Cause of death in clinical research: time for a reassessment?","volume":"34","author":"Lauer","year":"1999","journal-title":"J. Am. Coll. Cardiol."},{"issue":"3","key":"10.1016\/j.ijcard.2026.135004_bb0035","doi-asserted-by":"crossref","DOI":"10.3390\/jcm12030903","article-title":"Association of coronary computed tomography angiography and stress echocardiography with long-term cardiac outcome: a comparison study","volume":"12","author":"Gaibazzi","year":"2023","journal-title":"J. Clin. Med."},{"issue":"4","key":"10.1016\/j.ijcard.2026.135004_bb0040","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1007\/s10554-018-1501-3","article-title":"Drop-off in positivity rate of stress echocardiography based on regional wall motion abnormalities over the last three decades","volume":"35","author":"Cortigiani","year":"2019","journal-title":"Int. J. Card. Imaging"}],"container-title":["International Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527326008545?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167527326008545?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T17:51:37Z","timestamp":1793209897000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167527326008545"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":8,"alternative-id":["S0167527326008545"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcard.2026.135004","relation":{},"ISSN":["0167-5273"],"issn-type":[{"value":"0167-5273","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reversible wall motion abnormalities do not predict long-term mortality if coronary flow reserve is accounted for: A 15-year contrast stress-echo study","name":"articletitle","label":"Article Title"},{"value":"International Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcard.2026.135004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"135004"}}