{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:13:56Z","timestamp":1786990436375,"version":"build-2736575974"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,20]],"date-time":"2022-03-20T00:00:00Z","timestamp":1647734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006520","name":"Edwards Lifesciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006520","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001316","name":"Abbott Laboratories","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001316","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["IJC Heart & Vasculature"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.ijcha.2022.101013","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T23:31:10Z","timestamp":1648596670000},"page":"101013","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Predictive value of the APACHE II score in cardiogenic shock patients treated with a percutaneous left ventricular assist device"],"prefix":"10.1016","volume":"40","author":[{"given":"Johannes","family":"Mierke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Nowack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Loehn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franziska","family":"Kluge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederike","family":"Poege","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe","family":"Speiser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Woitek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norman","family":"Mangner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Linke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Pfluecke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcha.2022.101013_b0005","first-page":"220","article-title":"Scoring systems in the intensive care unit: A compendium, Indian","volume":"18","author":"Rapsang","year":"2014","journal-title":"J. Crit. Care Med."},{"issue":"8","key":"10.1016\/j.ijcha.2022.101013_b0010","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1097\/00003246-199508000-00005","article-title":"A comparison of severity of illness scoring systems for intensive care unit patients: results of a multicenter, multinational study. The European\/North American Severity Study Group","volume":"23","author":"Castella","year":"1995","journal-title":"Crit. Care Med."},{"issue":"4","key":"10.1016\/j.ijcha.2022.101013_b0015","doi-asserted-by":"crossref","first-page":"420","DOI":"10.4187\/respcare.00811","volume":"56","author":"Villar","year":"2011","journal-title":"Respir. Care."},{"issue":"2","key":"10.1016\/j.ijcha.2022.101013_b0020","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.transci.2016.10.005","article-title":"Use of the APACHE II score to assess impact of therapeutic plasma exchange for critically ill patients with hypertriglyceride-induced pancreatitis","volume":"56","author":"Nakhoda","year":"2017","journal-title":"Transfus Apher Sci."},{"issue":"2","key":"10.1016\/j.ijcha.2022.101013_b0025","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1177\/0310057X1504300206","article-title":"Efficacy of the APACHE II score at ICU discharge in predicting post-ICU mortality and ICU readmission in critically ill surgical patients","volume":"43","author":"Lee","year":"2015","journal-title":"Anaesth. Intensive Care"},{"key":"10.1016\/j.ijcha.2022.101013_b0030","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1097\/00003246-198510000-00009","article-title":"APACHE II: a severity of disease classification system","volume":"13","author":"Knaus","year":"1985","journal-title":"Crit. Care Med."},{"issue":"1","key":"10.1016\/j.ijcha.2022.101013_b0035","doi-asserted-by":"crossref","DOI":"10.1186\/s13054-019-2478-6","article-title":"Frequency and mortality of septic shock in Europe and North America: a systematic review and meta-analysis","volume":"23","author":"Vincent","year":"2019","journal-title":"Crit. Care"},{"issue":"1","key":"10.1016\/j.ijcha.2022.101013_b0040","doi-asserted-by":"crossref","DOI":"10.1186\/s13104-018-3830-7","article-title":"In-hospital mortality of patients with cardiogenic shock after acute myocardial infarction; impact of early revascularization","volume":"11","author":"Hashmi","year":"2018","journal-title":"BMC Res. Notes"},{"issue":"9","key":"10.1016\/j.ijcha.2022.101013_b0045","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1056\/NEJM199908263410901","article-title":"Early Revascularization in Acute Myocardial Infarction Complicated by Cardiogenic Shock","volume":"341","author":"Hochman","year":"1999","journal-title":"N. Engl. J. Med."},{"issue":"16","key":"10.1016\/j.ijcha.2022.101013_b0050","doi-asserted-by":"crossref","DOI":"10.1161\/CIR.0000000000000525","article-title":"Contemporary Management of Cardiogenic Shock: A Scientific Statement From the American Heart Association","volume":"136","author":"van Diepen","year":"2017","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.ijcha.2022.101013_b0055","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/S0002-8703(99)70250-4","article-title":"Continuous intravenous dobutamine is associated with an increased risk of death in patients with advanced heart failure: insights from the Flolan International Randomized Survival Trial (FIRST)","volume":"138","author":"O'Connor","year":"1999","journal-title":"Am. Heart J."},{"issue":"3","key":"10.1016\/j.ijcha.2022.101013_b0060","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/bcpt.12385","article-title":"Milrinone for the Treatment of Acute Heart Failure After Acute Myocardial Infarction: A Systematic Review and Meta-Analysis","volume":"117","author":"Tang","year":"2015","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"issue":"2","key":"10.1016\/j.ijcha.2022.101013_b0065","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.ijcard.2011.07.022","article-title":"Levosimendan: molecular mechanisms and clinical implications: consensus of experts on the mechanisms of action of levosimendan","volume":"159","author":"Papp","year":"2012","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcha.2022.101013_b0070","doi-asserted-by":"crossref","first-page":"2671","DOI":"10.1093\/eurheartj\/ehz363","article-title":"Management of cardiogenic shock complicating myocardial infarction: an update 2019","volume":"40","author":"Thiele","year":"2019","journal-title":"Eur. Heart J."},{"issue":"5","key":"10.1016\/j.ijcha.2022.101013_b0075","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1161\/CIRCULATIONAHA.110.945055","article-title":"Novel percutaneous cardiac assist devices: the science of and indications for hemodynamic support","volume":"123","author":"Naidu","year":"2011","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.ijcha.2022.101013_b0080","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1002\/ccd.20380","article-title":"Left ventricular unloading and concomitant total cardiac output increase by the use of percutaneous Impella Recover LP 2.5 assist device during high-risk coronary intervention","volume":"65","author":"Valgimigli","year":"2005","journal-title":"Catheterization and Cardiovascular Interventions : Official J. Soc. Cardiac Angiography & Interventions."},{"issue":"4","key":"10.1016\/j.ijcha.2022.101013_b0085","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1002\/ccd.21160","article-title":"Effects of left ventricular unloading by Impella recover LP2.5 on coronary hemodynamics","volume":"70","author":"Remmelink","year":"2007","journal-title":"Catheterization and Cardiovascular Interventions."},{"issue":"2","key":"10.1016\/j.ijcha.2022.101013_b0090","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/ccd.22263","article-title":"Effects of mechanical left ventricular unloading by impella on left ventricular dynamics in high-risk and primary percutaneous coronary intervention patients","volume":"75","author":"Remmelink","year":"2010","journal-title":"Catheterization and Cardiovascular Interventions."},{"key":"10.1016\/j.ijcha.2022.101013_b0095","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.ijcard.2014.10.153","article-title":"Support with intra-aortic balloon pump vs. Impella2.5(R) and blood flow to the heart, brain and kidneys - an experimental porcine model of ischaemic heart failure","volume":"178","author":"Moller-Helgestad","year":"2015","journal-title":"Int. J. Cardiol."},{"issue":"10","key":"10.1016\/j.ijcha.2022.101013_b0100","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1161\/CIRCULATIONAHA.118.036614","article-title":"Impella Support for Acute Myocardial Infarction Complicated by Cardiogenic Shock","volume":"139","author":"Schrage","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.ijcha.2022.101013_b0105","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1001\/jama.2020.0254","article-title":"Association of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock","volume":"323","author":"Dhruva","year":"2020","journal-title":"JAMA"},{"issue":"12","key":"10.1016\/j.ijcha.2022.101013_b0110","doi-asserted-by":"crossref","first-page":"3803","DOI":"10.3390\/jcm9123803","article-title":"Long-Term Clinical Outcome of Cardiogenic Shock Patients Undergoing Impella CP Treatment vs. Standard of Care","volume":"9","author":"Scherer","year":"2020","journal-title":"J. Clin. Med."},{"issue":"1","key":"10.1016\/j.ijcha.2022.101013_b0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/joic.12080","article-title":"The current use of Impella 2.5 in acute myocardial infarction complicated by cardiogenic shock: results from the USpella Registry","volume":"27","author":"O'neill","year":"2014","journal-title":"J. Interventional Cardiology"},{"issue":"2","key":"10.1016\/j.ijcha.2022.101013_b0120","first-page":"149","article-title":"Long term survival after early unloading with Impella CP \u00ae in acute myocardial infarction complicated by cardiogenic shock","volume":"9","author":"Loehn","year":"2020","journal-title":"Eur. Heart J.: Acute Cardiovascular Care."},{"issue":"4","key":"10.1016\/j.ijcha.2022.101013_b0125","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.hlc.2020.08.005","article-title":"Percutaneous Left Ventricular Assist Device Leads to Heart Rhythm Stabilisation in Cardiogenic Shock: Results from the Dresden Impella Registry","volume":"30","author":"Mierke","year":"2021","journal-title":"Heart, Lung and Circulation."},{"issue":"8","key":"10.1016\/j.ijcha.2022.101013_b0130","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1007\/s00063-013-0234-2","volume":"108","author":"Kellner","year":"2013","journal-title":"Med. Klin. Intensivmed. Notfmed."},{"issue":"3","key":"10.1016\/j.ijcha.2022.101013_b0135","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1007\/s00134-016-4223-9","article-title":"The ENCOURAGE mortality risk score and analysis of long-term outcomes after VA-ECMO for acute myocardial infarction with cardiogenic shock","volume":"42","author":"Muller","year":"2016","journal-title":"Intensive Care Med."},{"key":"10.1016\/j.ijcha.2022.101013_b0140","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1186\/s13054-020-03217-6","article-title":"Association between mean arterial pressure during the first 24 hours and hospital mortality in patients with cardiogenic shock","volume":"24","author":"Burstein","year":"2020","journal-title":"Crit. Care"},{"key":"10.1016\/j.ijcha.2022.101013_b0145","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1161\/CIRCULATIONAHA.108.814947","article-title":"Thirty-Year Trends (1975 to 2005) in the Magnitude of, Management of, and Hospital Death Rates Associated With Cardiogenic Shock in Patients With Acute Myocardial Infarction","volume":"119","author":"Goldberg","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.ijcha.2022.101013_b0150","doi-asserted-by":"crossref","unstructured":"N. Aissaoui, E. Puymirat, X. Tabone, B. Charbonnier, F. Schiele, T. Lef\u00e8vre, E. Durand, D. Blanchard, T. Simon, J.-P. Cambou, N. Danchin, Improved outcome of cardiogenic shock at the acute stage of myocardial infarction: a report from the USIK 1995, USIC 2000, and FAST-MI French nationwide registries, Eur. Heart J. 33 (2012) 2535\u20132543. https:\/\/doi.org\/10.1093\/eurheartj\/ehs264.","DOI":"10.1093\/eurheartj\/ehs264"},{"issue":"5","key":"10.1016\/j.ijcha.2022.101013_b0155","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1093\/bja\/aev284","article-title":"The Effect of inotropes and vasopressors on mortality: a meta-analysis of randomized clinical trials","volume":"115","author":"Belletti","year":"2015","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.ijcha.2022.101013_b0160","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1093\/eurjhf\/hfn045","article-title":"Levosimendan vs. dobutamine: outcomes for acute heart failure patients on beta-blockers in SURVIVE","volume":"11","author":"Mebazaa","year":"2009","journal-title":"Eur. J. Heart Fail."},{"issue":"3","key":"10.1016\/j.ijcha.2022.101013_b0165","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1093\/eurheartj\/eht248","article-title":"Mechanical circulatory support in cardiogenic shock","volume":"35","author":"Werdan","year":"2014","journal-title":"Eur. Heart J."},{"issue":"3","key":"10.1016\/j.ijcha.2022.101013_b0170","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1161\/CIRCULATIONAHA.118.038201","article-title":"Intraaortic Balloon Pump in Cardiogenic Shock Complicating Acute Myocardial Infarction: Long-Term 6-Year Outcome of the Randomized IABP-SHOCK II Trial","volume":"139","author":"Thiele","year":"2019","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.ijcha.2022.101013_b0175","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s00392-017-1182-2","article-title":"Trends in mechanical circulatory support use and hospital mortality among patients with acute myocardial infarction and non-infarction related cardiogenic shock in the United States","volume":"107","author":"Shah","year":"2018","journal-title":"Clin. Res. Cardiol."},{"issue":"3","key":"10.1016\/j.ijcha.2022.101013_b0180","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.jacc.2016.10.022","article-title":"Percutaneous Mechanical Circulatory Support Versus Intra-Aortic Balloon Pump in Cardiogenic Shock After Acute Myocardial Infarction","volume":"69","author":"Ouweneel","year":"2017","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcha.2022.101013_b0185","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.ahj.2019.04.019","article-title":"Rationale and design of DanGer shock: Danish-German cardiogenic shock trial","volume":"214","author":"Udesen","year":"2019","journal-title":"Am. Heart J."},{"issue":"3","key":"10.1016\/j.ijcha.2022.101013_b0190","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1177\/039139889902200306","article-title":"Changing acute renal failure treatment from intermittent hemodialysis to continuous hemofiltration: impact on azotemic control","volume":"22","author":"Bellomo","year":"1999","journal-title":"Int. J. Artif. Organs"},{"key":"10.1016\/j.ijcha.2022.101013_b0195","doi-asserted-by":"crossref","unstructured":"Acute Respiratory Distress Syndrome Network, R.G. Brower, M.A. Matthay, A. Morris, D. Schoenfeld, B.T. Thompson, A. Wheeler, Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome, N. Engl. J. Med. 342 (2000) 1301\u20131308. https:\/\/doi.org\/10.1056\/NEJM200005043421801.","DOI":"10.1056\/NEJM200005043421801"},{"issue":"14","key":"10.1016\/j.ijcha.2022.101013_b0200","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1056\/NEJMoa1208410","article-title":"Intraaortic Balloon Support for Myocardial Infarction with Cardiogenic Shock","volume":"367","author":"Thiele","year":"2012","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijcha.2022.101013_b0205","doi-asserted-by":"crossref","first-page":"97","DOI":"10.5644\/ama2006-124.165","article-title":"Predictive value of SAPS II and APACHE II scoring systems for patient outcome in a medical intensive care unit","volume":"45","author":"Godinjak","year":"2016","journal-title":"Acta Med. Acad."},{"key":"10.1016\/j.ijcha.2022.101013_b0210","first-page":"47","article-title":"Illness severity scoring for Intensive Care at Middlemore Hospital, New Zealand: past and future","volume":"123","author":"Mann","year":"2010","journal-title":"N. Z. Med. J."},{"issue":"2","key":"10.1016\/j.ijcha.2022.101013_b0215","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.jacc.2004.03.060","article-title":"Cardiac power is the strongest hemodynamic correlate of mortality in cardiogenic shock: A report from the SHOCK trial registry","volume":"44","author":"Fincke","year":"2004","journal-title":"J. Am. Coll. Cardiol."},{"issue":"19","key":"10.1016\/j.ijcha.2022.101013_b0220","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.1016\/j.jcin.2020.06.037","article-title":"Arterial Lactate in Cardiogenic Shock: Prognostic Value of Clearance Versus Single Values","volume":"13","author":"Fuernau","year":"2020","journal-title":"JACC Cardiovasc. Interv."},{"key":"10.1016\/j.ijcha.2022.101013_b0225","unstructured":"J. Mierke, T. Nowack, T. Loehn, F. Kluge, F. Poege, F. Woitek, N. Mangner, K. Ibrahim, A. Linke, C. Pfluecke, Data for validation and adjustment of APACHE II score in cardiogenic shock patients treated with a percutaneous left ventricular assist device. Data Brief. [submitted to Journal]."}],"container-title":["IJC Heart & Vasculature"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352906722000628?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352906722000628?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T05:12:33Z","timestamp":1762492353000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352906722000628"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":45,"alternative-id":["S2352906722000628"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcha.2022.101013","relation":{},"ISSN":["2352-9067"],"issn-type":[{"value":"2352-9067","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Predictive value of the APACHE II score in cardiogenic shock patients treated with a percutaneous left ventricular assist device","name":"articletitle","label":"Article Title"},{"value":"IJC Heart & Vasculature","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcha.2022.101013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101013"}}