{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:39:28Z","timestamp":1791931168724,"version":"4.3.4"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T00:00:00Z","timestamp":1667520000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008731","name":"Nakatomi Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002241","name":"Japan Science and Technology Agency","doi-asserted-by":"publisher","award":["JPMJPF210"],"award-info":[{"award-number":["JPMJPF210"]}],"id":[{"id":"10.13039\/501100002241","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008882","name":"Meiji Yasuda Kosei Jigyodan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008882","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008373","name":"Takeda Yakuhin Kogyo Kabushiki Kaisha","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008373","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["IJC Heart & Vasculature"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.ijcha.2022.101147","type":"journal-article","created":{"date-parts":[[2022,11,11]],"date-time":"2022-11-11T13:12:25Z","timestamp":1668172345000},"page":"101147","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Real-time analysis of heart rate variability during aerobic exercise in patients with cardiovascular disease"],"prefix":"10.1016","volume":"43","author":[{"given":"Hidehiko","family":"Ikura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinori","family":"Katsumata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Seki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshinobu","family":"Ryuzaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuyuki","family":"Shiraishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kotaro","family":"Miura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuki","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiichi","family":"Fukuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcha.2022.101147_b0005","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.jacc.2014.11.023","article-title":"Dose of jogging and long-term mortality: The Copenhagen City heart study","volume":"65","author":"Schnohr","year":"2015","journal-title":"J Am Coll Cardiol."},{"key":"10.1016\/j.ijcha.2022.101147_b0010","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1016\/S0140-6736(11)60749-6","article-title":"Minimum amount of physical activity for reduced mortality and extended life expectancy: A prospective cohort study","volume":"378","author":"Wen","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.ijcha.2022.101147_b0015","doi-asserted-by":"crossref","first-page":"659","DOI":"10.7326\/0003-4819-143-9-200511010-00010","article-title":"Meta-Analysis: Secondary Prevention Programs for Patients withcoronary artery disease","volume":"143","author":"Clark","year":"2005","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.ijcha.2022.101147_b0020","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1001\/jama.2009.457","article-title":"Effects of exercise training on health status in patients with chronic heart failure: HF-ACTION randomized controlled trial","volume":"301","author":"Flynn","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.ijcha.2022.101147_b0025","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1016\/j.jacc.2012.06.036","article-title":"10-year exercise training in chronic heart failure: a randomized controlled trial","volume":"60","author":"Belardinelli","year":"2012","journal-title":"J. Am. Coll. Cardiol."},{"issue":"1","key":"10.1016\/j.ijcha.2022.101147_b0030","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1054\/jcaf.2003.2","article-title":"A practical guide to exercise training for heart failure patients","volume":"9","author":"Smart","year":"2003","journal-title":"J. Card. Fail."},{"key":"10.1016\/j.ijcha.2022.101147_b0035","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1161\/01.CIR.0000055013.92097.40","article-title":"Exercise and heart failure: A statement from the American Heart Association Committee on exercise, rehabilitation, and prevention","volume":"107","author":"Pi\u00f1a","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.ijcha.2022.101147_b0040","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1161\/01.CIR.0000047275.25795.17","article-title":"Short-term heart rate variability strongly predicts sudden cardiac death in chronic heart failure patients","volume":"107","author":"La Rovere","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.ijcha.2022.101147_b0045","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0140-6736(05)78676-1","article-title":"Autonomic markers and prediction of cardiac death after myocardial infarction","volume":"351","author":"Barron","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.ijcha.2022.101147_b0050","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1056\/NEJM197605202942107","article-title":"Neural activity and ventricular fibrillation","volume":"294","author":"Lown","year":"1976","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijcha.2022.101147_b0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1758-5996-3-1","article-title":"Noninvasive method to estimate anaerobic threshold in individuals with type 2 diabetes","volume":"3","author":"Sales","year":"2011","journal-title":"Diabetol Metab Syndr."},{"key":"10.1016\/j.ijcha.2022.101147_b0060","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1055\/s-2007-989423","article-title":"Use of heart rate variability to estimate LT and VT","volume":"29","author":"Karapetian","year":"2008","journal-title":"Int. J. Sports Med."},{"key":"10.1016\/j.ijcha.2022.101147_b0065","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1055\/s-2006-923849","article-title":"Assessment of ventilatory thresholds from heart rate variability in well-trained subjects during cycling","volume":"27","author":"Cottin","year":"2006","journal-title":"Int. J. Sports Med."},{"key":"10.1016\/j.ijcha.2022.101147_b0070","doi-asserted-by":"crossref","first-page":"e006612","DOI":"10.1161\/JAHA.117.006612","article-title":"Real-time analysis of the heart rate variability during incremental exercise for the detection of the ventilatory threshold","volume":"7","author":"Shiraishi","year":"2018","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.ijcha.2022.101147_b0075","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1097\/00005768-200111000-00007","article-title":"Validity and reliability of combining three methods to determine ventilatory threshold","volume":"33","author":"Gaskill","year":"2001","journal-title":"Med Sci Sports Exerc."},{"issue":"8476","key":"10.1016\/j.ijcha.2022.101147_b0080","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0140-6736(86)90837-8","article-title":"Statistical methods for assessing agreement between two methods of clinical measurement","volume":"327","author":"Martin Bland","year":"1986","journal-title":"Lancet"},{"key":"10.1016\/j.ijcha.2022.101147_b0085","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.tcm.2017.02.005","article-title":"The role of cardiac rehabilitation in patients with heart disease","volume":"27","author":"McMahon","year":"2017","journal-title":"Trends Cardiovasc. Med."},{"key":"10.1016\/j.ijcha.2022.101147_b0090","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/HJR.0b013e328334ea56","article-title":"Can a heart failure-specific cardiac rehabilitation program decrease hospitalizations and improve outcomes in high-risk patients?","volume":"17","author":"Davidson","year":"2010","journal-title":"Eur J Cardiovasc Prev Rehabil."},{"key":"10.1016\/j.ijcha.2022.101147_b0095","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.1161\/CIRCULATIONAHA.110.983536","article-title":"Impact of cardiac rehabilitation on mortality and cardiovascular events after percutaneous coronary intervention in the community","volume":"123","author":"Goel","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.ijcha.2022.101147_b0100","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1136\/bmj.328.7441.711-b","article-title":"Exercise training meta-analysis of trials in patients with chronic heart failure (ExTraMATCH)","volume":"328","author":"Piepoli","year":"2004","journal-title":"BMJ"},{"key":"10.1016\/j.ijcha.2022.101147_b0105","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0002-9149(98)00774-7","article-title":"Comparison of ramp versus step protocols for exercise testing in patients > or = 60 years of age","volume":"83","author":"Bader","year":"1999","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ijcha.2022.101147_b0110","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1253\/circj.CJ-66-0094","article-title":"Guidelines for rehabilitation in patients with cardiovascular disease (JCS 2012)","volume":"78","author":"JCS Joint Working Group","year":"2014","journal-title":"Circ. J."},{"key":"10.1016\/j.ijcha.2022.101147_b0115","article-title":"JCS\/JACR 2021 guideline on rehabilitation in patients with cardiovascular disease (in Japanese)","author":"Makita","year":"2021","journal-title":"Circ. J."},{"key":"10.1016\/j.ijcha.2022.101147_b0120","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1253\/circj.CJ-19-0241","article-title":"Nationwide survey of multidisciplinary care and cardiac rehabilitation for patients with heart failure in japan - an analysis of the AMED-CHF study","volume":"83","author":"Kamiya","year":"2019","journal-title":"Circ. J."},{"key":"10.1016\/j.ijcha.2022.101147_b0125","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.pcad.2013.12.001","article-title":"Current state of cardiac rehabilitation in Japan","volume":"56","author":"Goto","year":"2014","journal-title":"Prog. Cardiovasc. Dis."},{"key":"10.1016\/j.ijcha.2022.101147_b0130","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1253\/circj.71.173","article-title":"Poor implementation of cardiac rehabilitation despite broad dissemination of coronary interventions for acute myocardial infarction in Japan: a nationwide survey","volume":"71","author":"Goto","year":"2007","journal-title":"Circ. J."},{"key":"10.1016\/j.ijcha.2022.101147_b0135","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1161\/CIRCULATIONAHA.107.701466","article-title":"Use of cardiac rehabilitation by Medicare beneficiaries after myocardial infarction or coronary bypass surgery","volume":"116","author":"Suaya","year":"2007","journal-title":"Circulation"},{"issue":"17","key":"10.1016\/j.ijcha.2022.101147_b0140","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1056\/NEJM199410273311706","article-title":"Use of medical resources and quality of life after acute myocardial infarction in Canada and the United States","volume":"331","author":"Mark","year":"1994","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijcha.2022.101147_b0145","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1001\/archinte.1992.00400170113021","article-title":"Predictors of cardiac rehabilitation participation in older coronary patients","volume":"152","author":"Ades","year":"1992","journal-title":"Arch. Intern. Med."}],"container-title":["IJC Heart & Vasculature"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352906722001968?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352906722001968?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T21:18:08Z","timestamp":1778879888000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352906722001968"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":29,"alternative-id":["S2352906722001968"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcha.2022.101147","relation":{},"ISSN":["2352-9067"],"issn-type":[{"value":"2352-9067","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Real-time analysis of heart rate variability during aerobic exercise in patients with cardiovascular disease","name":"articletitle","label":"Article Title"},{"value":"IJC Heart & Vasculature","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcha.2022.101147","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101147"}}