{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T17:38:35Z","timestamp":1790444315311,"version":"4.1.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T00:00:00Z","timestamp":1689552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013826","name":"Candys Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002918","name":"Gentofte Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002918","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["IJC Heart & Vasculature"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.ijcha.2023.101250","type":"journal-article","created":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T23:21:56Z","timestamp":1691536916000},"page":"101250","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Kinetics of cardiac troponin and other biomarkers in patients with ST elevation myocardial infarction"],"prefix":"10.1016","volume":"48","author":[{"given":"Jonas","family":"Henrik Kristensen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Amalie Wistisen Koczulab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emil","family":"Anton Frandsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasmus","family":"Bo Hasselbalch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Strandkj\u00e6r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicoline","family":"J\u00f8rgensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"\u00d8stergaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Hasse M\u00f8ller-S\u00f8rensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Christian Nilsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoaib","family":"Afzal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pia","family":"R\u00f8rb\u00e6k Kamstrup","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"Dahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa Vakur","family":"Bor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Frikke-Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niklas","family":"Rye J\u00f8rgensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Line","family":"Rode","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lene","family":"Holmvang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesper","family":"Kj\u00e6rgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lia","family":"Evi Bang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Forman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim","family":"Dalhoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henning","family":"Bundgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kasper","family":"Karmark Iversen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcha.2023.101250_b0005","doi-asserted-by":"crossref","first-page":"e618","DOI":"10.1161\/CIR.0000000000000617","article-title":"Fourth Universal Definition of Myocardial Infarction (2018)","volume":"138","author":"Thygesen","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.ijcha.2023.101250_b0010","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1093\/eurheartj\/eht210","article-title":"Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: A position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases","volume":"34","author":"Caforio","year":"2013","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcha.2023.101250_b0015","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1016\/0022-2828(89)90680-9","article-title":"Enzyme linked immuno assay of cardiac troponin T for the detection of acute myocardial infarction in patients","volume":"21","author":"Katus","year":"1989","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.ijcha.2023.101250_b0020","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1515\/cclm-2014-0475","article-title":"Kinetics of high-sensitivity cardiac troponin T or troponin I compared to creatine kinase in patients with revascularized acute myocardial infarction","volume":"53","author":"Solecki","year":"2015","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.ijcha.2023.101250_b0025","first-page":"354","article-title":"Kinetics of high-sensitivity cardiac troponin T and I differ in patients with ST-segment elevation myocardial infarction treated by primary coronary intervention","volume":"5","author":"Laugaudin","year":"2016","journal-title":"Eur. Heart J. Acute Cardiovasc. Care"},{"key":"10.1016\/j.ijcha.2023.101250_b0030","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.3390\/cimb44030092","article-title":"Features of the Metabolisms of Cardiac Troponin Molecules\u2014Part 1: The Main Stages of Metabolism","volume":"44","author":"Chaulin","year":"2022","journal-title":"Release Stage, Current Issues in Molecular Biology."},{"key":"10.1016\/j.ijcha.2023.101250_b0035","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.clinbiochem.2017.02.007","article-title":"Clearance of cardiac troponin T with and without kidney function","volume":"50","author":"Frid\u00e9n","year":"2017","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.ijcha.2023.101250_b0040","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1007\/s11095-017-2219-y","article-title":"Influence of Molecular size on the clearance of antibody fragments","volume":"34","author":"Li","year":"2017","journal-title":"Pharm. Res."},{"key":"10.1016\/j.ijcha.2023.101250_b0045","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1373\/49.7.1191","article-title":"Renal elimination of troponin T and troponin I","volume":"49","author":"Ziebig","year":"2003","journal-title":"Clin. Chem."},{"key":"10.1016\/j.ijcha.2023.101250_b0050","unstructured":"IFCC Committee on Clinical Applications of Cardiac Bio-markers, High-Sensitivity* Cardiac Troponin I and T Assay Analytical Characteristics Designated by Manufacturer IFCC Committee on Clinical Applications of Cardiac Bio-Markers (C-CB) v082318, (2019) 1\u20134. http:\/\/www.ifcc.org\/media\/477441\/high-sensitivity-cardiac-troponin-i-and-t-assay-analytical-characteristics-designated-by-manufacturer-v08232018.pdf (accessed June 28, 2022)."},{"key":"10.1016\/j.ijcha.2023.101250_b0055","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)-A metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J. Biomed. Inform."},{"key":"10.1016\/j.ijcha.2023.101250_b0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbi.2019.103208","article-title":"The REDCap consortium: Building an international community of software platform partners","volume":"95","author":"Harris","year":"2019","journal-title":"J. Biomed. Inform."},{"key":"10.1016\/j.ijcha.2023.101250_b0065","first-page":"1","article-title":"Acute Phase Response and Non-Reproducible Elevated Concentrations with a High-Sensitivity Cardiac Troponin I Assay, Journal of","volume":"10","author":"Kavsak","year":"2021","journal-title":"Clin. Med."},{"key":"10.1016\/j.ijcha.2023.101250_b0070","doi-asserted-by":"crossref","unstructured":"M.P.F. Maintainer, M.P. Fay, Package \u201casht,\u201d (2023). https:\/\/doi.org\/10.1002\/bimj.201600111.","DOI":"10.1002\/bimj.201600111"},{"key":"10.1016\/j.ijcha.2023.101250_b0075","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.yexmp.2008.07.002","article-title":"Release kinetics of intact and degraded troponin I and T after irreversible cell damage","volume":"85","author":"Hessel","year":"2008","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.ijcha.2023.101250_b0080","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.yexmp.2014.02.012","article-title":"Cardiac troponin in ischemic cardiomyocytes: Intracellular decrease before onset of cell death","volume":"96","author":"Streng","year":"2014","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.ijcha.2023.101250_b0085","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1161\/CIRCULATIONAHA.120.046574","article-title":"Temporal Release of High-Sensitivity Cardiac Troponin T and I and Copeptin after Brief Induced Coronary Artery Balloon Occlusion in Humans","volume":"143","author":"\u00c1rnad\u00f3ttir","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.ijcha.2023.101250_b0090","first-page":"979","article-title":"Release of cardiac troponin I from viable cardiomyocytes is mediated by integrin stimulation, Pflugers Archiv European","volume":"455","author":"Hessel","year":"2008","journal-title":"J. Physiol."},{"key":"10.1016\/j.ijcha.2023.101250_b0095","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1067\/mhj.2001.111767","article-title":"Evidence of cardiac myolysis in severe nonischemic heart failure and the potential role of increased wall strain","volume":"141","author":"Logeart","year":"2001","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ijcha.2023.101250_b0100","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1093\/clinchem\/45.12.2129","article-title":"RNA expression of cardiac troponin T isoforms in diseased human skeletal muscle","volume":"45","author":"Ricchiuti","year":"1999","journal-title":"Clin. Chem."},{"key":"10.1016\/j.ijcha.2023.101250_b0105","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1373\/clinchem.2013.217943","article-title":"Revision of the troponin T release mechanism from damaged human myocardium","volume":"60","author":"Starnberg","year":"2014","journal-title":"Clin. Chem."},{"key":"10.1016\/j.ijcha.2023.101250_b0110","doi-asserted-by":"crossref","first-page":"3401","DOI":"10.1161\/01.CIR.92.12.3401","article-title":"Value of myoglobin, troponin T, and CK-MBmass in ruling out an acute myocardial infarction in the emergency room","volume":"92","author":"De Winter","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.ijcha.2023.101250_b0115","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1373\/clinchem.2018.301127","article-title":"Full-size and partially truncated cardiac troponin complexes in the blood of patients with acute myocardial infarction","volume":"65","author":"Vylegzhanina","year":"2019","journal-title":"Clin. Chem."},{"key":"10.1016\/j.ijcha.2023.101250_b0120","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1111\/aor.13835","article-title":"Modeling the transfer of low molecular weight plasma proteins during hemodialysis and online hemodiafiltration","volume":"45","author":"Glancey","year":"2021","journal-title":"Artif. Organs"},{"key":"10.1016\/j.ijcha.2023.101250_b0125","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0009-8981(97)00252-0","article-title":"Assessment of left ventricular function using serum cardiac troponin I measurements following myocardial infarction","volume":"272","author":"Apple","year":"1998","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.ijcha.2023.101250_b0130","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.2042-3306.2012.00554.x","article-title":"Elimination half-life of intravenously administered equine cardiac troponin I in healthy ponies","volume":"45","author":"Kraus","year":"2013","journal-title":"Equine Vet. J."},{"key":"10.1016\/j.ijcha.2023.101250_b0135","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1093\/toxsci\/kfr190","article-title":"The complete pharmacokinetic profile of serum cardiac troponin I in the rat and the dog","volume":"123","author":"Dunn","year":"2011","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.ijcha.2023.101250_b0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12872-017-0485-6","article-title":"Association of serum transaminases with short- and long-term outcomes in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention","volume":"17","author":"Gao","year":"2017","journal-title":"BMC Cardiovasc. Disord."},{"key":"10.1016\/j.ijcha.2023.101250_b0145","doi-asserted-by":"crossref","DOI":"10.1093\/eurheartj\/ehy655","article-title":"Fourth universal definition of myocardial infarction (2018)","author":"Thygesen","year":"2018","journal-title":"Eur Heart J."},{"key":"10.1016\/j.ijcha.2023.101250_b0150","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.ijcard.2018.05.136","article-title":"Circadian rhythm of cardiac troponin I and its clinical impact on the diagnostic accuracy for acute myocardial infarction","volume":"270","author":"Wildi","year":"2018","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcha.2023.101250_b0155","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1373\/clinchem.2016.257485","article-title":"Diurnal rhythm of cardiac troponin: Consequences for the diagnosis of acute myocardial infarction","volume":"62","author":"Klinkenberg","year":"2016","journal-title":"Clin. Chem."},{"key":"10.1016\/j.ijcha.2023.101250_b0160","unstructured":"Udmeldinger om alkohol - Sundhedsstyrelsen, (n.d.). https:\/\/www.sst.dk\/da\/viden\/Forebyggelse\/Alkohol\/Alkoholforebyggelse\/Sundhedsstyrelsens-udmeldinger-om-alkohol (accessed April 13, 2023)."}],"container-title":["IJC Heart & Vasculature"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352906723000817?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352906723000817?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T05:13:16Z","timestamp":1762492396000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352906723000817"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":32,"alternative-id":["S2352906723000817"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcha.2023.101250","relation":{},"ISSN":["2352-9067"],"issn-type":[{"value":"2352-9067","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Kinetics of cardiac troponin and other biomarkers in patients with ST elevation myocardial infarction","name":"articletitle","label":"Article Title"},{"value":"IJC Heart & Vasculature","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcha.2023.101250","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101250"}}