{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T13:17:06Z","timestamp":1763644626967,"version":"build-2065373602"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T00:00:00Z","timestamp":1745366400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004826","name":"Beijing Natural Science Foundation","doi-asserted-by":"publisher","award":["L2322116"],"award-info":[{"award-number":["L2322116"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["IJC Heart & Vasculature"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.ijcha.2025.101689","type":"journal-article","created":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T19:29:27Z","timestamp":1746559767000},"page":"101689","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["QFR measurements post CTO percutaneous coronary intervention: Can the long term outcome be predicted?"],"prefix":"10.1016","volume":"59","author":[{"given":"Yanguo","family":"Xin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiayu","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaosong","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuhe","family":"Gong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcha.2025.101689_b0005","doi-asserted-by":"crossref","first-page":"2364","DOI":"10.1161\/CIRCULATIONAHA.104.481283","article-title":"Percutaneous recanalization of chronically occluded coronary arteries: a consensus document: part I","volume":"112","author":"Stone","year":"2005","journal-title":"Circulation."},{"key":"10.1016\/j.ijcha.2025.101689_b0010","doi-asserted-by":"crossref","first-page":"198","DOI":"10.4244\/EIJ-D-18-00826","article-title":"Percutaneous recanalisation of chronic total occlusions: 2019 consensus document from the EuroCTO Club","volume":"15","author":"Galassi","year":"2019","journal-title":"EuroIntervention."},{"key":"10.1016\/j.ijcha.2025.101689_b0015","article-title":"Prognostic Impact of Percutaneous Coronary Intervention of Chronic Total Occlusion in Acute and Periprocedural Myocardial Infarction","volume":"10","author":"Kim","year":"2021","journal-title":"J Clin Med."},{"key":"10.1016\/j.ijcha.2025.101689_b0020","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/s00392-009-0013-5","article-title":"Chronic total coronary occlusions in patients with stable angina pectoris: impact on therapy and outcome in present day clinical practice","volume":"98","author":"Werner","year":"2009","journal-title":"Clin Res Cardiol."},{"key":"10.1016\/j.ijcha.2025.101689_b0025","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/j.jacc.2011.12.007","article-title":"Current perspectives on coronary chronic total occlusions: the Canadian Multicenter Chronic Total Occlusions Registry","volume":"59","author":"Fefer","year":"2012","journal-title":"J Am Coll Cardiol."},{"key":"10.1016\/j.ijcha.2025.101689_b0030","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1161\/CIRCULATIONAHA.119.039797","article-title":"Guiding Principles for Chronic Total Occlusion Percutaneous Coronary Intervention","volume":"140","author":"Brilakis","year":"2019","journal-title":"Circulation."},{"key":"10.1016\/j.ijcha.2025.101689_b0035","doi-asserted-by":"crossref","first-page":"e123","DOI":"10.4244\/EIJ-D-22-00694","article-title":"Changes in absolute flow, myocardial resistance and FFR after chronic total occlusion percutaneous coronary intervention","volume":"19","author":"Khan","year":"2023","journal-title":"EuroIntervention."},{"key":"10.1016\/j.ijcha.2025.101689_b0040","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1016\/j.jacc.2016.07.744","article-title":"Percutaneous Intervention for ConcurrentChronic Total Occlusions inPatients WithSTEMI: The EXPLORE Trial","volume":"68","author":"Henriques","year":"2016","journal-title":"J Am Coll Cardiol."},{"key":"10.1016\/j.ijcha.2025.101689_b0045","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1016\/j.jcin.2017.05.065","article-title":"Early Procedural and Health Status Outcomes After Chronic Total OcclusionAngioplasty: A Report From the OPEN-CTO Registry (Outcomes, Patient Health Status, and Efficiency in Chronic Total Occlusion Hybrid Procedures)","volume":"10","author":"Sapontis","year":"2017","journal-title":"JACC Cardiovasc Interv."},{"key":"10.1016\/j.ijcha.2025.101689_b0050","doi-asserted-by":"crossref","first-page":"3189","DOI":"10.1093\/eurheartj\/ehv450","article-title":"Management strategies in patients affected by chronic total occlusions: results from the Italian Registry of Chronic Total Occlusions","volume":"36","author":"Tomasello","year":"2015","journal-title":"Eur Heart J."},{"key":"10.1016\/j.ijcha.2025.101689_b0055","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jcin.2014.10.010","article-title":"Long-term survival benefit of revascularization compared with medical therapy in patients with coronary chronic total occlusion and well-developed collateral circulation","volume":"8","author":"Jang","year":"2015","journal-title":"JACC Cardiovasc Interv."},{"key":"10.1016\/j.ijcha.2025.101689_b0060","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.ahj.2020.02.015","article-title":"Quantitative flow ratio-guided strategy versus angiography-guided strategy for percutaneous coronary intervention: Rationale and design of the FAVOR III China trial","volume":"223","author":"Song","year":"2020","journal-title":"Am Heart J."},{"key":"10.1016\/j.ijcha.2025.101689_b0065","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1016\/j.jcin.2016.07.013","article-title":"Diagnostic Accuracy of Fast Computational Approaches to DeriveFractional Flow Reserve FromDiagnostic Coronary Angiography: The International Multicenter FAVOR Pilot Study","volume":"9","author":"Tu","year":"2016","journal-title":"JACC Cardiovasc Interv."},{"key":"10.1016\/j.ijcha.2025.101689_b0070","doi-asserted-by":"crossref","first-page":"3077","DOI":"10.1016\/j.jacc.2017.10.035","article-title":"Diagnostic Accuracy of Angiography-Based Quantitative FlowRatio Measurements for Online Assessmentof Coronary Stenosis","volume":"70","author":"Xu","year":"2017","journal-title":"J Am Coll Cardiol."},{"key":"10.1016\/j.ijcha.2025.101689_b0075","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.009603","article-title":"Diagnostic Performance of In-Procedure Angiography-Derived Quantitative Flow Reserve Compared to Pressure-Derived Fractional Flow Reserve: The FAVOR II Europe-Japan Study","volume":"7","author":"Westra","year":"2018","journal-title":"J Am Heart Assoc."},{"key":"10.1016\/j.ijcha.2025.101689_b0080","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1016\/S0140-6736(21)02248-0","article-title":"Angiographic quantitative flow ratio-guided coronary intervention (FAVOR III China): a multicentre, randomised, sham-controlled trial","volume":"398","author":"Xu","year":"2021","journal-title":"Lancet."},{"issue":"Suppl 1","key":"10.1016\/j.ijcha.2025.101689_b0085","first-page":"624","article-title":"Novel application of quantitative flow ratio for predicting microvascular dysfunction after ST-segment-elevation myocardial infarction","volume":"95","author":"Sheng","year":"2020","journal-title":"Catheter Cardiovasc Interv."},{"key":"10.1016\/j.ijcha.2025.101689_b0090","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1186\/s13098-022-00926-6","article-title":"Association of haemoglobin glycation index with outcomes in patients with acute coronary syndrome: results from an observational cohort study in China","volume":"14","author":"Li","year":"2022","journal-title":"Diabetol Metab Syndr."},{"key":"10.1016\/j.ijcha.2025.101689_b0095","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.011605","article-title":"Diagnostic Agreement of Quantitative Flow Ratio With Fractional Flow Reserve and Instantaneous Wave-Free Ratio","volume":"8","author":"Hwang","year":"2019","journal-title":"J Am Heart Assoc."},{"key":"10.1016\/j.ijcha.2025.101689_b0100","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.ijcard.2022.05.066","article-title":"Diagnostic performance of quantitative flow ratio versus fractional flow reserve and resting full-cycle ratio in intermediate coronary lesions","volume":"362","author":"Wienemann","year":"2022","journal-title":"Int J Cardiol."},{"key":"10.1016\/j.ijcha.2025.101689_b0105","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1016\/S0140-6736(24)02175-5","article-title":"Quantitative flow ratio versus fractional flow reserve for coronary revascularisation guidance (FAVOR III Europe): a multicentre, randomised, non-inferiority trial","volume":"404","author":"Andersen","year":"2024","journal-title":"Lancet."},{"key":"10.1016\/j.ijcha.2025.101689_b0110","doi-asserted-by":"crossref","unstructured":"Tonino PA, De Bruyne B, Pijls NH, Siebert U, Ikeno F, van' t Veer M, Klauss V, Manoharan G, Engstr\u00f8m T, Oldroyd KG, et al. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med. 2009;360:213-224. doi: 10.1056\/NEJMoa0807611.","DOI":"10.1056\/NEJMoa0807611"},{"key":"10.1016\/j.ijcha.2025.101689_b0115","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1056\/NEJMoa1205361","article-title":"Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease","volume":"367","author":"De Bruyne","year":"2012","journal-title":"N Engl J Med."},{"key":"10.1016\/j.ijcha.2025.101689_b0120","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.117.007107","article-title":"Evaluation of Coronary Artery Stenosis by Quantitative Flow Ratio During Invasive Coronary Angiography: The WIFI II Study (Wire-Free Functional Imaging II)","volume":"11","author":"Westra","year":"2018","journal-title":"Circ Cardiovasc Imaging."},{"key":"10.1016\/j.ijcha.2025.101689_b0125","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1016\/j.jcin.2019.06.003","article-title":"Prognostic Value of QFR Measured Immediately After Successful Stent Implantation: The International Multicenter Prospective HAWKEYE Study","volume":"12","author":"Biscaglia","year":"2019","journal-title":"JACC Cardiovasc Interv."},{"key":"10.1016\/j.ijcha.2025.101689_b0130","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1016\/j.jcin.2019.08.009","article-title":"Clinical Implication of Quantitative Flow Ratio After Percutaneous Coronary Intervention for 3-Vessel Disease","volume":"12","author":"Kogame","year":"2019","journal-title":"JACC Cardiovasc Interv."},{"key":"10.1016\/j.ijcha.2025.101689_b0135","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.jcin.2012.05.004","article-title":"The recanalization of chronic total occlusion leads to lumen area increase in distal reference segments in selected patients: an intravascular ultrasound study","volume":"5","author":"Park","year":"2012","journal-title":"JACC Cardiovasc Interv."},{"key":"10.1016\/j.ijcha.2025.101689_b0140","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.4244\/EIJV9I10A199","article-title":"Lumen enlargement of the coronary segments located distal to chronic total occlusions successfully treated with drug-eluting stents at follow-up","volume":"9","author":"Gomez-Lara","year":"2014","journal-title":"EuroIntervention."},{"key":"10.1016\/j.ijcha.2025.101689_b0145","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.amjcard.2015.11.055","article-title":"Serial Intravascular Ultrasound Findings After Treatment of Chronic Total Occlusions Using Drug-Eluting Stents","volume":"117","author":"Saito","year":"2016","journal-title":"Am J Cardiol."},{"key":"10.1016\/j.ijcha.2025.101689_b0150","first-page":"1071","article-title":"Microvascular dysfunction in the immediate aftermath of chronic total coronary occlusion recanalization","volume":"87","author":"Ladwiniec","year":"2016","journal-title":"Catheter Cardiovasc Interv."},{"key":"10.1016\/j.ijcha.2025.101689_b0155","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.jcin.2016.12.009","article-title":"Coronary Collaterals Function and Clinical Outcome Between Patients With Acute and Chronic Total Occlusion","volume":"10","author":"Lee","year":"2017","journal-title":"JACC Cardiovasc Interv."},{"key":"10.1016\/j.ijcha.2025.101689_b0160","doi-asserted-by":"crossref","first-page":"2877","DOI":"10.1161\/01.CIR.0000100724.44398.01","article-title":"Regression of collateral function after recanalization of chronic total coronary occlusions: a serial assessment by intracoronary pressure and Doppler recordings","volume":"108","author":"Werner","year":"2003","journal-title":"Circulation."},{"key":"10.1016\/j.ijcha.2025.101689_b0165","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jacc.2005.12.079","article-title":"Rapid decline of collateral circulation increases susceptibility to myocardial ischemia: the trade-off of successful percutaneous recanalization of chronic total occlusions","volume":"48","author":"Zimarino","year":"2006","journal-title":"J Am Coll Cardiol."},{"key":"10.1016\/j.ijcha.2025.101689_b0170","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.118.006941","article-title":"Serial Fractional Flow Reserve Measurements Post Coronary Chronic Total Occlusion Percutaneous Coronary Intervention","volume":"11","author":"Karamasis","year":"2018","journal-title":"Circ Cardiovasc Interv."}],"container-title":["IJC Heart & Vasculature"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352906725000922?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352906725000922?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T17:18:18Z","timestamp":1762622298000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352906725000922"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":34,"alternative-id":["S2352906725000922"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcha.2025.101689","relation":{},"ISSN":["2352-9067"],"issn-type":[{"type":"print","value":"2352-9067"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"QFR measurements post CTO percutaneous coronary intervention: Can the long term outcome be predicted?","name":"articletitle","label":"Article Title"},{"value":"IJC Heart & Vasculature","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcha.2025.101689","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101689"}}