{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:48:37Z","timestamp":1786654117968,"version":"build-2736575974"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:00:00Z","timestamp":1781827200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministry of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["IJC Heart & Vasculature"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.ijcha.2026.101962","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T18:01:33Z","timestamp":1782237693000},"page":"101962","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Implementation of guideline-directed medical therapy among patients with acute heart failure admitted to cardiac rehabilitation: the PROMETEO registry"],"prefix":"10.1016","volume":"65","author":[{"given":"Alessandro","family":"Villaschi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Letizia","family":"Oreni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasia","family":"Toccafondi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignazio","family":"Cusmano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Gonella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Gonella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaia","family":"Coni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Torri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Grati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Ambrosetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Cianflone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuccia","family":"Morici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijcha.2026.101962_bb0005","doi-asserted-by":"crossref","first-page":"3272","DOI":"10.1093\/cvr\/cvac013","article-title":"Global burden of heart failure: a comprehensive and updated review of epidemiology","volume":"118","author":"Savarese","year":"2023","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.ijcha.2026.101962_bb0010","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1002\/ejhf.3506","article-title":"Trends in heart failure mortality in Sweden between 1997 and 2022","volume":"27","author":"Lindberg","year":"2025","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcha.2026.101962_bb0015","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1002\/ejhf.1311","article-title":"Impact of exercise-based cardiac rehabilitation in patients with heart failure (ExTraMATCH II) on mortality and hospitalisation: an individual patient data meta-analysis of randomised trials","volume":"20","author":"Taylor","year":"2018","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcha.2026.101962_bb0020","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.jchf.2019.04.023","article-title":"Exercise-based rehabilitation for heart failure: Cochrane systematic review, Meta-analysis, and trial sequential analysis","volume":"7","author":"Taylor","year":"2019","journal-title":"JACC Heart Fail"},{"key":"10.1016\/j.ijcha.2026.101962_bb0025","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1093\/eurheartj\/ehab368","article-title":"2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"42","author":"McDonagh","year":"2021","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcha.2026.101962_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.cpcardiol.2023.102058","article-title":"Use of optimal medical therapy in patients with cardiovascular disease undergoing cardiac rehabilitation","volume":"49","author":"Jafri","year":"2024","journal-title":"Curr. Probl. Cardiol."},{"key":"10.1016\/j.ijcha.2026.101962_bb0035","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1161\/CIRCULATIONAHA.122.061046","article-title":"A new era in cardiac rehabilitation delivery: research gaps, questions, strategies, and priorities","volume":"147","author":"Beatty","year":"2023","journal-title":"Circulation"},{"key":"10.1016\/j.ijcha.2026.101962_bb0040","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.jchf.2021.05.007","article-title":"Rehabilitation intervention in older patients with acute heart failure with preserved versus reduced ejection fraction","volume":"9","author":"Mentz","year":"2021","journal-title":"JACC Heart Fail"},{"key":"10.1016\/j.ijcha.2026.101962_bb0045","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1056\/NEJMoa2407107","article-title":"Finerenone in heart failure with mildly reduced or preserved ejection fraction","volume":"391","author":"Solomon","year":"2024","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijcha.2026.101962_bb0050","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1056\/NEJMoa2206286","article-title":"Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction","volume":"387","author":"Solomon","year":"2022","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijcha.2026.101962_bb0055","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.jacc.2021.11.033","article-title":"Optimal background pharmacological therapy for heart failure patients in clinical trials: JACC review topic of the week","volume":"79","author":"Fiuzat","year":"2022","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcha.2026.101962_bb0060","doi-asserted-by":"crossref","first-page":"3627","DOI":"10.1093\/eurheartj\/ehad195","article-title":"2023 focused update of the 2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"44","author":"McDonagh","year":"2023","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ijcha.2026.101962_bb0065","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1056\/NEJMoa1005419","article-title":"Diuretic strategies in patients with acute decompensated heart failure","volume":"364","author":"Felker","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijcha.2026.101962_bb0070","doi-asserted-by":"crossref","first-page":"e117","DOI":"10.1093\/eurjpc\/zwae182","article-title":"Cardiac rehabilitation registries around the globe: current status and future needs","volume":"31","author":"Grace","year":"2024","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.ijcha.2026.101962_bb0075","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1016\/j.jacc.2021.01.030","article-title":"Cardiac rehabilitation for patients with heart failure: JACC expert panel","volume":"77","author":"Bozkurt","year":"2021","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcha.2026.101962_bb0080","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1177\/2047487314520783","article-title":"Sex bias in referral of women to outpatient cardiac rehabilitation? A meta-analysis","volume":"22","author":"Colella","year":"2015","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.ijcha.2026.101962_bb0085","article-title":"Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction","volume":"3","author":"Basile","year":"2025","journal-title":"Glob. Cardiol."},{"key":"10.1016\/j.ijcha.2026.101962_bb0090","article-title":"Age- and sex-related differences in heart failure characteristics and treatment patterns across the ejection fraction spectrum: first data from the BRING-UP-3 heart failure study","author":"Basile","year":"2025","journal-title":"Eur. Heart J. Qual. Care Clin. Outcomes"},{"key":"10.1016\/j.ijcha.2026.101962_bb0095","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1186\/s12872-021-02267-0","article-title":"Nature, availability, and utilization of women-focused cardiac rehabilitation: a systematic review","volume":"21","author":"Mamataz","year":"2021","journal-title":"BMC Cardiovasc. Disord."},{"key":"10.1016\/j.ijcha.2026.101962_bb0100","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1001\/jama.2009.457","article-title":"Effects of exercise training on health status in patients with chronic heart failure: HF-ACTION randomized controlled trial","volume":"301","author":"Flynn","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.ijcha.2026.101962_bb0105","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1002\/ejhf.3234","article-title":"Frailty according to the 2019 HFA-ESC definition in patients at risk for advanced heart failure: insights from the HELP-HF registry","volume":"26","author":"Villaschi","year":"2024","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcha.2026.101962_bb0110","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1002\/ejhf.3112","article-title":"The role of multimorbidity in patients with heart failure across the left ventricular ejection fraction spectrum: data from the Swedish heart failure registry","volume":"26","author":"Tomasoni","year":"2024","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcha.2026.101962_bb0115","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1007\/s11739-020-02304-4","article-title":"Characteristics of current heart failure patients admitted to internal medicine vs. cardiology hospital units: the VASCO study","volume":"15","author":"Ricciardi","year":"2020","journal-title":"Intern. Emerg. Med."},{"key":"10.1016\/j.ijcha.2026.101962_bb0120","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1002\/ehf2.15187","article-title":"Assessment of frailty in patients with heart failure: a new heart failure frailty score developed by Delphi consensus","volume":"12","author":"Vitale","year":"2025","journal-title":"ESC Heart Fail."},{"key":"10.1016\/j.ijcha.2026.101962_bb0125","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1016\/S0140-6736(22)02076-1","article-title":"Safety, tolerability and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial","volume":"400","author":"Mebazaa","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.ijcha.2026.101962_bb0130","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1002\/ejhf.3565","article-title":"Implementation of guideline-recommended therapies in heart failure with reduced ejection fraction according to heart failure duration: an analysis of 55 581 patients from the Swedish heart failure (SwedeHF) registry","volume":"27","author":"Shahim","year":"2025","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcha.2026.101962_bb0135","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1002\/ejhf.2971","article-title":"Real-world use of sodium-glucose cotransporter 2 inhibitors in patients with heart failure and reduced ejection fraction: data from the Swedish heart failure registry","volume":"25","author":"Stolfo","year":"2023","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcha.2026.101962_bb0140","article-title":"Contemporary medical therapy for heart failure across the ejection fraction spectrum: the OPTIPHARM-HF registry","author":"Inciardi","year":"2025","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcha.2026.101962_bb0145","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.124.012547","article-title":"Multiregional implementation initiative\u2019s impact on guideline-based performance measures for patients hospitalized with heart failure: IMPLEMENT-HF","volume":"18","author":"Sauer","year":"2025","journal-title":"Circ. Heart Fail."},{"key":"10.1016\/j.ijcha.2026.101962_bb0150","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jchf.2018.10.010","article-title":"Contemporary drug treatment of chronic heart failure with reduced ejection fraction","volume":"7","author":"Brunner-La Rocca","year":"2019","journal-title":"JACC Heart Fail."},{"key":"10.1016\/j.ijcha.2026.101962_bb0155","doi-asserted-by":"crossref","first-page":"e1008","DOI":"10.1016\/S2214-109X(18)30306-1","article-title":"Prescribing patterns of evidence-based heart failure pharmacotherapy and outcomes in the ASIAN-HF registry: a cohort study","volume":"6","author":"Teng","year":"2018","journal-title":"Lancet Glob. Health"},{"key":"10.1016\/j.ijcha.2026.101962_bb0160","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.jacc.2018.04.070","article-title":"Medical therapy for heart failure with reduced ejection fraction: the CHAMP-HF registry","volume":"72","author":"Greene","year":"2018","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcha.2026.101962_bb0165","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1002\/ejhf.2477","article-title":"Association between dosing and combination use of medications and outcomes in heart failure with reduced ejection fraction: data from the Swedish heart failure registry","volume":"24","author":"D\u2019Amario","year":"2022","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcha.2026.101962_bb0170","doi-asserted-by":"crossref","DOI":"10.15420\/ecr.2021.33","article-title":"Management of Heart Failure in patients with chronic kidney disease","volume":"17","author":"Ryan","year":"2022","journal-title":"Eur Cardiol"},{"key":"10.1016\/j.ijcha.2026.101962_bb0175","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1002\/ejhf.3295","article-title":"How to tackle therapeutic inertia in heart failure with reduced ejection fraction. A scientific statement of the heart failure association of the ESC","volume":"26","author":"Savarese","year":"2024","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ijcha.2026.101962_bb0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jchf.2022.08.009","article-title":"Heart failure drug treatment-inertia, titration, and discontinuation: a multinational observational study (EVOLUTION HF)","volume":"11","author":"Savarese","year":"2023","journal-title":"JACC Heart Fail"},{"key":"10.1016\/j.ijcha.2026.101962_bb0185","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1056\/NEJMoa2107038","article-title":"Empagliflozin in heart failure with a preserved ejection fraction","volume":"385","author":"Anker","year":"2021","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijcha.2026.101962_bb0190","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.ijcard.2018.01.067","article-title":"Prevalence, predictors and clinical outcome of residual congestion in acute decompensated heart failure","volume":"258","author":"Rubio-Gracia","year":"2018","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcha.2026.101962_bb0195","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1016\/j.jacc.2019.12.059","article-title":"Diuretic therapy for patients with heart failure: JACC state-of-the-art review","volume":"75","author":"Felker","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcha.2026.101962_bb0200","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.jacc.2024.04.055","article-title":"Effects of rapid uptitration of Neurohormonal blockade on effective, sustainable decongestion and outcomes in STRONG-HF","volume":"84","author":"Biegus","year":"2024","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcha.2026.101962_bb0205","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1161\/CIRCULATIONAHA.120.045691","article-title":"Empagliflozin in heart failure: diuretic and Cardiorenal effects","volume":"142","author":"Griffin","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.ijcha.2026.101962_bb0210","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1001\/archinte.158.1.26","article-title":"Hyperkalemia in outpatients using angiotensin-converting enzyme inhibitors. How much should we worry?","volume":"158","author":"Reardon","year":"1998","journal-title":"Arch. Intern. Med."}],"container-title":["IJC Heart & Vasculature"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352906726000965?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352906726000965?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:25:08Z","timestamp":1786652708000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352906726000965"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":42,"alternative-id":["S2352906726000965"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcha.2026.101962","relation":{},"ISSN":["2352-9067"],"issn-type":[{"value":"2352-9067","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Implementation of guideline-directed medical therapy among patients with acute heart failure admitted to cardiac rehabilitation: the PROMETEO registry","name":"articletitle","label":"Article Title"},{"value":"IJC Heart & Vasculature","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcha.2026.101962","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101962"}}