{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:48:19Z","timestamp":1786654099757,"version":"build-2736575974"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:00:00Z","timestamp":1783555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100020595","name":"Taiwan Ministry of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["IJC Heart & Vasculature"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.ijcha.2026.101973","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T18:51:34Z","timestamp":1784659894000},"page":"101973","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Peripheral microvascular function and long-term cardiovascular outcomes after percutaneous coronary intervention in patients with obstructive coronary artery disease"],"prefix":"10.1016","volume":"65","author":[{"given":"Ya-Wen","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan-Tsai","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Chin","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruey-Hsing","family":"Chou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chin-Sung","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Hsun","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9859","key":"10.1016\/j.ijcha.2026.101973_bb0005","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1016\/S0140-6736(12)61728-0","article-title":"Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010","volume":"380","author":"Lozano","year":"2012","journal-title":"Lancet"},{"issue":"23","key":"10.1016\/j.ijcha.2026.101973_bb0010","doi-asserted-by":"crossref","first-page":"e443","DOI":"10.1161\/CIR.0000000000001394","article-title":"State of the art: evaluation and medical management of nonobstructive coronary artery disease in patients with chest pain: a scientific statement from the American Heart Association","volume":"152","author":"Slipczuk","year":"2025","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.ijcha.2026.101973_bb0015","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/joic.12508","article-title":"Percutaneous coronary intervention: 2017 in review","volume":"31","author":"Rao","year":"2018","journal-title":"J. Interv. Cardiol."},{"issue":"29","key":"10.1016\/j.ijcha.2026.101973_bb0020","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1093\/eurheartj\/ehy857","article-title":"Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization","volume":"40","author":"Crea","year":"2019","journal-title":"Eur. Heart J."},{"issue":"5","key":"10.1016\/j.ijcha.2026.101973_bb0025","doi-asserted-by":"crossref","DOI":"10.1093\/ehjopen\/oead083","article-title":"In-stent restenosis after percutaneous coronary intervention: emerging knowledge on biological pathways","volume":"3","author":"Pelliccia","year":"2023","journal-title":"Eur. Heart J. Open"},{"issue":"4","key":"10.1016\/j.ijcha.2026.101973_bb0030","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.jacc.2005.04.055","article-title":"Endothelial vasomotor dysfunction in the brachial artery is associated with late in-stent coronary restenosis","volume":"46","author":"Kitta","year":"2005","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ijcha.2026.101973_bb0035","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.ijcard.2014.10.039","article-title":"Flow-mediated dilation is associated with cardiovascular events in non-valvular atrial fibrillation patients","volume":"179","author":"Perri","year":"2015","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ijcha.2026.101973_bb0040","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/7967324","article-title":"Flow-mediated dilatation in the assessment of coronary heart disease: a meta-analysis","volume":"2022","author":"Xiao","year":"2022","journal-title":"Cardiol. Res. Pract."},{"issue":"1","key":"10.1016\/j.ijcha.2026.101973_bb0045","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1464-5491.2008.02609.x","article-title":"Relationship between post-occlusive forearm skin reactive hyperaemia and vascular disease in patients with Type 2 diabetes--a novel index for detecting micro- and macrovascular dysfunction using laser Doppler flowmetry","volume":"26","author":"Yamamoto-Suganuma","year":"2009","journal-title":"Diabet. Med."},{"issue":"7","key":"10.1016\/j.ijcha.2026.101973_bb0050","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.tips.2013.05.007","article-title":"Assessment of endothelial and neurovascular function in human skin microcirculation","volume":"34","author":"Roustit","year":"2013","journal-title":"Trends Pharmacol. Sci."},{"issue":"4","key":"10.1016\/j.ijcha.2026.101973_bb0055","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/cpf.12819","article-title":"Assessing skin microcirculation in patients at cardiovascular risk by using laser speckle contrast imaging. A narrative review","volume":"43","author":"Lazaridis","year":"2023","journal-title":"Clin. Physiol. Funct. Imaging"},{"issue":"2","key":"10.1016\/j.ijcha.2026.101973_bb0060","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.vascn.2004.11.003","article-title":"Reproducibility of different laser Doppler fluximetry parameters of postocclusive reactive hyperemia in human forearm skin","volume":"52","author":"Yvonne-Tee","year":"2005","journal-title":"J. Pharmacol. Toxicol. Methods"},{"issue":"10","key":"10.1016\/j.ijcha.2026.101973_bb0065","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1161\/ATVBAHA.107.147322","article-title":"Predictive value of reactive hyperemia for cardiovascular events in patients with peripheral arterial disease undergoing vascular surgery","volume":"27","author":"Huang","year":"2007","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"5","key":"10.1016\/j.ijcha.2026.101973_bb0070","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1161\/ATVBAHA.121.316083","article-title":"Impaired peripheral microvascular function and risk of major adverse cardiovascular events in patients with coronary artery disease","volume":"41","author":"Young","year":"2021","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"1","key":"10.1016\/j.ijcha.2026.101973_bb0075","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/s12882-016-0303-x","article-title":"Microvascular endothelial dysfunction is associated with albuminuria and CKD in older adults","volume":"17","author":"Seliger","year":"2016","journal-title":"BMC Nephrol."},{"issue":"3","key":"10.1016\/j.ijcha.2026.101973_bb0080","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1038\/s41440-021-00838-4","article-title":"Clinical implication of impaired skin microvascular function in patients with hypertension","volume":"45","author":"Maruhashi","year":"2022","journal-title":"Hypertens. Res."},{"key":"10.1016\/j.ijcha.2026.101973_bb0085","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.mvr.2016.09.003","article-title":"Cutaneous microvascular reactivity and aortic elasticity in coronary artery disease: comparison of the laser Doppler flowmetry and echocardiography","volume":"109","author":"\u00c7eki\u00e7","year":"2017","journal-title":"Microvasc. Res."},{"issue":"5","key":"10.1016\/j.ijcha.2026.101973_bb0090","doi-asserted-by":"crossref","DOI":"10.1111\/micc.12692","article-title":"A systematic evaluation of cutaneous microcirculation in the foot using post-occlusive reactive hyperemia","volume":"28","author":"Balasubramanian","year":"2021","journal-title":"Microcirculation"},{"issue":"1","key":"10.1016\/j.ijcha.2026.101973_bb0095","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.ijcard.2012.09.047","article-title":"Flow-mediated dilation and cardiovascular risk prediction: a systematic review with meta-analysis","volume":"168","author":"Ras","year":"2013","journal-title":"Int. J. Cardiol."},{"issue":"22","key":"10.1016\/j.ijcha.2026.101973_bb0100","article-title":"A comprehensive review of clinical studies applying flow-mediated dilation","volume":"14","author":"Ahn","year":"2024","journal-title":"Diagnostics (Basel)"},{"issue":"7","key":"10.1016\/j.ijcha.2026.101973_bb0105","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1253\/circrep.CR-25-0042","article-title":"Improvement of cardiovascular prognostic value of endothelial function tests by repeated measurements","volume":"7","author":"Masaki","year":"2025","journal-title":"Circ. Rep."},{"issue":"12","key":"10.1016\/j.ijcha.2026.101973_bb0110","first-page":"1997","article-title":"Relationship between brachial artery flow-mediated dilation and coronary flow reserve in patients with peripheral artery disease","volume":"46","author":"Pellegrino","year":"2005","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.ijcha.2026.101973_bb0115","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.carrev.2023.02.003","article-title":"Impact of endothelial dysfunction on long-term clinical outcomes in patients with chronic coronary syndromes treated with second generation drug-eluting stent implantation","volume":"51","author":"Paolucci","year":"2023","journal-title":"Cardiovasc. Revasc. Med."},{"issue":"9","key":"10.1016\/j.ijcha.2026.101973_bb0120","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1042\/CS20070431","article-title":"Relationship between peripheral and coronary function using laser Doppler imaging and transthoracic echocardiography","volume":"115","author":"Khan","year":"2008","journal-title":"Clin. Sci. (Lond.)"},{"key":"10.1016\/j.ijcha.2026.101973_bb0125","article-title":"Association of microvascular dysfunction with clinical outcomes in patients with non-flow limiting fractional flow reserve after percutaneous coronary intervention","volume":"35","author":"Nishi","year":"2021","journal-title":"Int. J. Cardiol. Heart. Vasc."},{"issue":"4","key":"10.1016\/j.ijcha.2026.101973_bb0130","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.124.036033","article-title":"Microcirculatory resistance after primary percutaneous coronary intervention predicts residual myocardial damage and scar formation","volume":"14","author":"Candreva","year":"2025","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.ijcha.2026.101973_bb0135","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.yjmcc.2024.06.002","article-title":"Is the peripheral microcirculation a window into the human coronary microvasculature?","volume":"193","author":"SenthilKumar","year":"2024","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"7","key":"10.1016\/j.ijcha.2026.101973_bb0140","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1161\/ATVBAHA.119.312378","article-title":"Peripheral microvascular function reflects coronary vascular function","volume":"39","author":"Al-Badri","year":"2019","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"11","key":"10.1016\/j.ijcha.2026.101973_bb0145","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1016\/j.jacc.2004.08.062","article-title":"Noninvasive identification of patients with early coronary atherosclerosis by assessment of digital reactive hyperemia","volume":"44","author":"Bonetti","year":"2004","journal-title":"J. Am. Coll. Cardiol."}],"container-title":["IJC Heart & Vasculature"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352906726001077?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352906726001077?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:23:09Z","timestamp":1786652589000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352906726001077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":29,"alternative-id":["S2352906726001077"],"URL":"https:\/\/doi.org\/10.1016\/j.ijcha.2026.101973","relation":{},"ISSN":["2352-9067"],"issn-type":[{"value":"2352-9067","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Peripheral microvascular function and long-term cardiovascular outcomes after percutaneous coronary intervention in patients with obstructive coronary artery disease","name":"articletitle","label":"Article Title"},{"value":"IJC Heart & Vasculature","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijcha.2026.101973","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101973"}}