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Recent studies have shown that though less sensitive to several behavioral indices of intoxication by ethanol, adolescent rats are more sensitive to the cognition\u2010impairing effects of ethanol. Ethanol's effects, in the present experiment, were assessed in terms of a fear conditioning test not previously used in comparison of adult and adolescent Sprague\u2013Dawley albino rats. Separate groups of both ages were given intraperitoneal (i.p.) ethanol before or after tone\u2013shock conditioning. This task features a hippocampus\u2010independent component, learned freezing to a tone, and a hippocampus\u2010dependent component, learned freezing to context. Post\u2010training ethanol had no effect on retention in either age, but pre\u2010acquisition ethanol impaired adult learning more than adolescent learning, as indexed by the expression of fear at the test. Blood alcohol was equivalent in adolescents and adults at a dose that produced cognitive discrepancies. Unlike other reports, these experiments demonstrate that adolescents may not be more sensitive to ethanol's effects in all cases of learning.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijdevneu.2004.04.008","type":"journal-article","created":{"date-parts":[[2004,7,15]],"date-time":"2004-07-15T12:20:42Z","timestamp":1089894042000},"page":"355-362","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Fear conditioning is impaired in adult rats by ethanol doses that do not affect periadolescents"],"prefix":"10.1002","volume":"22","author":[{"given":"Cantey","family":"Land","sequence":"first","affiliation":[{"name":"Center for Developmental Psychobiology Binghamton University Binghamton NY 13902 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norman E.","family":"Spear","sequence":"additional","affiliation":[{"name":"Center for Developmental Psychobiology Binghamton University Binghamton NY 13902 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,7,14]]},"reference":[{"issue":"3","key":"e_1_2_9_2_1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0741-8329(01)00127-6","article-title":"Age\u2010independent and dose\u2010response effects of ethanol on spatial memory in rats","volume":"23","author":"Acheson S.K.","year":"2002","journal-title":"Alcohol"},{"issue":"7","key":"e_1_2_9_3_1","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1111\/j.1530-0277.1998.tb03932.x","article-title":"Impairment of semantic and figural memory by acute ethanol: age\u2010dependent effects","volume":"22","author":"Acheson S.K.","year":"1998","journal-title":"Alcohol.: Clin. 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