{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T09:00:19Z","timestamp":1790413219228,"version":"4.1.0"},"reference-count":140,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T00:00:00Z","timestamp":1542672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["SAF2015\u201069187R"],"award-info":[{"award-number":["SAF2015\u201069187R"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J of Devlp Neuroscience"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:p>Evidence obtained in recent decades has demonstrated that the brain still matures in adolescence. Changes in neural connectivity occur in different regions, including cortical and subcortical structures, which undergo modifications in white and gray matter densities. These alterations concomitantly occur in some neurotransmitter systems and hormone secretion, which markedly influence the refinement of certain brain areas and neural circuits. The immaturity of the adolescent brain makes it more vulnerable to the effects of alcohol and drug abuse, whose use can trigger long\u2010term behavioral dysfunction. This article reviews the action of alcohol and drug abuse (cannabis, cocaine, opioids, amphetamines, anabolic androgenic steroids) in the adolescent brain, and their impact on both cognition and behavioral dysfunction, including predisposition to drug abuse in later life. It also discusses recent evidence that indicates the role of the neuroimmune system response and neuroinflammation as mechanisms that participate in many actions of ethanol and drug abuse in adolescence, including the neurotoxicity and alterations in neurocircuitry that contribute to the dysfunctional behaviors associated with addiction. The new data suggest the therapeutic potential of anti\u2010inflammatory targets to prevent the long\u2010term consequences of drug abuse in adolescence.<\/jats:p>","DOI":"10.1016\/j.ijdevneu.2018.11.006","type":"journal-article","created":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T08:32:07Z","timestamp":1542702727000},"page":"89-98","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["Impact of neuroimmune activation induced by alcohol or drug abuse on adolescent brain development"],"prefix":"10.1002","volume":"77","author":[{"given":"Consuelo","family":"Guerri","sequence":"first","affiliation":[{"name":"Department of Molecular and Cellular Pathology of Alcohol Pr\u00edncipe Felipe Research Center Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Pascual","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cellular Pathology of Alcohol Pr\u00edncipe Felipe Research Center Valencia Spain"},{"name":"Department of Physiology School of Medicine and Dentistry University of Valencia Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,20]]},"reference":[{"issue":"1","key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"S165","DOI":"10.1016\/j.bbi.2011.03.002","article-title":"Minocycline reduces ethanol drinking","volume":"25","author":"Agrawal R.G.","year":"2011","journal-title":"Brain Behav. Immun."},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/acer.13525"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e318238bba6"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2012.12.007"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0976-10.2010"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-015-1760-5"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2014.00216"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2001.00563.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/adb.12365"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.325.7374.1212"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.03.025"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/syn.890080403"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-006-0322-6"},{"issue":"1","key":"e_1_2_7_15_1","doi-asserted-by":"crossref","first-page":"E181","DOI":"10.1111\/j.1530-0277.2012.01920.x","article-title":"Longitudinal changes in white matter integrity among adolescent substance users","volume":"37","author":"Bava S.","year":"2013","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-017-0774-1"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2008.05425.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.175.10.6893"},{"issue":"1","key":"e_1_2_7_19_1","doi-asserted-by":"crossref","first-page":"S92","DOI":"10.1016\/j.bbi.2011.01.008","article-title":"Activation of inflammatory signaling by lipopolysaccharide produces a prolonged increase of voluntary alcohol intake in mice","volume":"25","author":"Blednov Y.A.","year":"2011","journal-title":"Brain Behav. Immun."},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/adb.12263"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2017.08.012"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1988.03410230059028"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.2174\/092986712803988947"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-013-1221-7"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cobeha.2016.12.003"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/0706743716645289"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.104.073023"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-017-0525-z"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1124\/pr.115.012138"},{"issue":"1","key":"e_1_2_7_30_1","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1016\/j.bbi.2011.03.003","article-title":"Induction of innate immune genes in brain create the neurobiology of addiction","volume":"25","author":"Crews F.T.","year":"2011","journal-title":"Brain Behav. Immun."},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2013.00129"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1308.001"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0361-9230(94)90189-9"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.alc.0000179368.87886.76"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2013.03.001"},{"key":"e_1_2_7_36_1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/s12974-016-0553-3","article-title":"Methamphetamine alters microglial immune function through P2X7R signaling","volume":"13","author":"Fernandes N.C.","year":"2016","journal-title":"J. Neuroinflammation"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0803590"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/hup.1251"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.12060"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2014.109"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2007.06.036"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0402680101"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.alcohol.2009.10.003"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-009-1579-3"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0684-12.2012"},{"key":"e_1_2_7_46_1","doi-asserted-by":"crossref","unstructured":"I.Ibarra\u2010Lecue I.Mollinedo\u2010Gajate J.J.Meana L.F.Callado R.Diez\u2010Alarcia L.Uriguen.Chronic cannabis promotes pro\u2010hallucinogenic signaling of 5\u2010HT2A receptors through Akt\/mTOR pathway.Neuropsychopharmacology2018","DOI":"10.1038\/s41386-018-0076-y"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dcn.2015.04.006"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-clinpsy-050212-185610"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.2174\/13816128113199990426"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(02)02310-7"},{"key":"e_1_2_7_51_1","first-page":"294","article-title":"Cannabinoid receptors in the central nervous system: their signaling and roles in disease","volume":"10","author":"Kendall D.A.","year":"2016","journal-title":"Front. Cell. Neurosci."},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00011.2010"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145709009924"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4899-1648-8_11"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20211"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/adb.12404"},{"key":"e_1_2_7_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2004.01.010"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742-2094-9-230"},{"key":"e_1_2_7_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.12519"},{"key":"e_1_2_7_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2010.01.007"},{"key":"e_1_2_7_61_1","doi-asserted-by":"crossref","DOI":"10.1371\/annotation\/89e38eb6-e8e3-402d-a6fb-84ebf9fcbb27","article-title":"Sex\u2010dependent psychoneuroendocrine effects of THC and MDMA in an animal model of adolescent drug consumption","volume":"8","author":"Llorente\u2010Berzal A.","year":"2013","journal-title":"PLoS One"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2009.03.007"},{"key":"e_1_2_7_63_1","doi-asserted-by":"publisher","DOI":"10.2478\/s11535-008-0058-x"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000624"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2007.00602.x"},{"key":"e_1_2_7_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/41131"},{"key":"e_1_2_7_67_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-1364"},{"key":"e_1_2_7_68_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007691-200404000-00008"},{"key":"e_1_2_7_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/acer.13208"},{"key":"e_1_2_7_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2018.05.049"},{"key":"e_1_2_7_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2014.11.015"},{"key":"e_1_2_7_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2015.12.006"},{"key":"e_1_2_7_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2010.06794.x"},{"key":"e_1_2_7_74_1","volume-title":"Drugs of Abuse: Opioids. Abuse NIoD (ed)","author":"NIDA","year":"2015"},{"key":"e_1_2_7_75_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M311618200"},{"key":"e_1_2_7_76_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2014.177"},{"key":"e_1_2_7_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2011.02.005"},{"key":"e_1_2_7_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2015.03.019"},{"key":"e_1_2_7_79_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269881104047286"},{"key":"e_1_2_7_80_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2006.05298.x"},{"key":"e_1_2_7_81_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2008.05835.x"},{"key":"e_1_2_7_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2012.01.011"},{"key":"e_1_2_7_83_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.24203"},{"key":"e_1_2_7_84_1","doi-asserted-by":"publisher","DOI":"10.1111\/adb.12461"},{"key":"e_1_2_7_85_1","doi-asserted-by":"publisher","DOI":"10.1093\/alcalc\/agt164"},{"key":"e_1_2_7_86_1","doi-asserted-by":"publisher","DOI":"10.15288\/jsad.2011.72.106"},{"key":"e_1_2_7_87_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-042617-053158"},{"key":"e_1_2_7_88_1","doi-asserted-by":"publisher","DOI":"10.2174\/1570159X13666141210222725"},{"key":"e_1_2_7_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2010.06.065"},{"key":"e_1_2_7_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ntt.2006.10.002"},{"key":"e_1_2_7_91_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4475"},{"key":"e_1_2_7_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2014.06.031"},{"key":"e_1_2_7_93_1","doi-asserted-by":"publisher","DOI":"10.1006\/nlme.2002.4103"},{"key":"e_1_2_7_94_1","doi-asserted-by":"publisher","DOI":"10.1111\/adb.12376"},{"key":"e_1_2_7_95_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-016-1196-y"},{"key":"e_1_2_7_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbb.2009.05.015"},{"key":"e_1_2_7_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(03)02563-0"},{"key":"e_1_2_7_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.alcohol.2008.05.002"},{"key":"e_1_2_7_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2016.07.036"},{"key":"e_1_2_7_100_1","doi-asserted-by":"publisher","DOI":"10.2174\/1874473711104020081"},{"key":"e_1_2_7_101_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1179-08.2008"},{"key":"e_1_2_7_102_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2015.00077"},{"key":"e_1_2_7_103_1","doi-asserted-by":"crossref","first-page":"102","DOI":"10.3126\/kumj.v11i1.11055","article-title":"Is central nervous system an immune\u2010privileged site?","volume":"11","author":"Shrestha R.","year":"2013","journal-title":"Kathmandu Univ. Med. J. KUMJ (KUMJ)"},{"key":"e_1_2_7_104_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.14263"},{"key":"e_1_2_7_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2014.03.001"},{"key":"e_1_2_7_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2007.08.003"},{"key":"e_1_2_7_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-013-8555-y"},{"key":"e_1_2_7_108_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-009-0619-8"},{"key":"e_1_2_7_109_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.21-22-08819.2001"},{"key":"e_1_2_7_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2016.07.026"},{"key":"e_1_2_7_111_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-011-2500-4"},{"key":"e_1_2_7_112_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0016516"},{"key":"e_1_2_7_113_1","article-title":"Ethane\u2010\u03b2\u2010sultam modifies the activation of the innate immune system induced by intermittent ethanol administration in female adolescent rats","volume":"2","author":"Stefanini C.","year":"2014","journal-title":"J. Alcohol. Drug Depend."},{"key":"e_1_2_7_114_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1308.005"},{"key":"e_1_2_7_115_1","doi-asserted-by":"publisher","DOI":"10.1177\/019262330002800104"},{"key":"e_1_2_7_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2009.10.008"},{"key":"e_1_2_7_117_1","doi-asserted-by":"publisher","DOI":"10.1037\/neu0000259"},{"key":"e_1_2_7_118_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-006-0641-7"},{"key":"e_1_2_7_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2004.06.065"},{"key":"e_1_2_7_120_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742-2094-9-155"},{"key":"e_1_2_7_121_1","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1080\/10678281003634926","article-title":"Crack and cocaine use among adolescents in psychiatric treatment: associations with HIV risk","volume":"19","author":"Tolou\u2010Shams M.","year":"2010","journal-title":"J. Child Adolesc. Subst. Abuse"},{"key":"e_1_2_7_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2012.04.026"},{"key":"e_1_2_7_123_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ALC.0000156453.05028.F5"},{"key":"e_1_2_7_124_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-3639.2004.tb00079.x"},{"key":"e_1_2_7_125_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0113421"},{"key":"e_1_2_7_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2012.08.046"},{"key":"e_1_2_7_127_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2015.00035"},{"key":"e_1_2_7_128_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2018.00200"},{"key":"e_1_2_7_129_1","doi-asserted-by":"publisher","DOI":"10.1111\/adb.12232"},{"key":"e_1_2_7_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2014.10.027"},{"key":"e_1_2_7_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpag.2011.01.061"},{"key":"e_1_2_7_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2017.11.019"},{"key":"e_1_2_7_133_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2009.06389.x"},{"key":"e_1_2_7_134_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn783"},{"key":"e_1_2_7_135_1","volume-title":"Global Status Report on Alcohol and Health","author":"WHO","year":"2014"},{"key":"e_1_2_7_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsat.2011.08.005"},{"key":"e_1_2_7_137_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1371-12.2013"},{"key":"e_1_2_7_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2015.09.021"},{"key":"e_1_2_7_139_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-018-1130-8"},{"key":"e_1_2_7_140_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.10.5780"},{"key":"e_1_2_7_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.steroids.2013.10.005"}],"container-title":["International Journal of Developmental Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073657481830251X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073657481830251X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2Fj.ijdevneu.2018.11.006","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.ijdevneu.2018.11.006","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.ijdevneu.2018.11.006","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.ijdevneu.2018.11.006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T02:26:47Z","timestamp":1694053607000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1016\/j.ijdevneu.2018.11.006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,20]]},"references-count":140,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1016\/j.ijdevneu.2018.11.006"],"URL":"https:\/\/doi.org\/10.1016\/j.ijdevneu.2018.11.006","archive":["Portico"],"relation":{},"ISSN":["0736-5748","1873-474X"],"issn-type":[{"value":"0736-5748","type":"print"},{"value":"1873-474X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,20]]},"assertion":[{"value":"2018-08-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}