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Thirty\u2010five ADHD and forty\u2010two children were examined by resting\u2010state functional magnetic resonance imaging (fMRI) scans. Data analysis was done via the degree centrality (DC) and voxel\u2010mirrored homotopic connectivity (VMHC) approaches. Compared with healthy subjects, the ADHD group exhibited significantly decreased DC values in the right posterior cingulate gyrus, left medial superior frontal gyrus, right inferior parietal gyrus, right middle frontal gyrus, left superior frontal gyrus and right superior frontal gyrus. Children with ADHD also exhibited some areas with increased DC values compared with healthy children. These regions included the cerebellar anterior lobe, right middle occipital cortex, left middle cingulate gyrus and right middle cingulate gyrus. VMHC analysis all revealed positive activation in a range of brain regions when comparing ADHD and normal children, suggesting that the VMHC scores of children with ADHD were higher in the bilateral superior frontal lobe, bilateral middle occipital lobe, and bilateral cerebellar anterior lobes. This work provides a new approach for examining the neural mechanisms underlying ADHD, demonstrating that the DC and VMHC methods enabled more comprehensive analysis that can be cross\u2010checked.<\/jats:p>","DOI":"10.1016\/j.ijdevneu.2019.07.003","type":"journal-article","created":{"date-parts":[[2019,7,12]],"date-time":"2019-07-12T15:29:18Z","timestamp":1562945358000},"page":"1-6","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Functional network connectivity changes in children with attention\u2010deficit hyperactivity disorder: A resting\u2010state fMRI study"],"prefix":"10.1002","volume":"78","author":[{"given":"Kaihua","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Children's Health Research Center Changzhou Children's Hospital Changzhou 213003 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Yi","sequence":"additional","affiliation":[{"name":"Department of Children's Health Research Center Changzhou Children's Hospital Changzhou 213003 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Children's Health Research Center Changzhou Children's Hospital Changzhou 213003 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongxin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Children's Health Research Center Changzhou Children's Hospital Changzhou 213003 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huijuan","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Children's Health Research Center Changzhou Children's Hospital Changzhou 213003 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangqiao","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Children's Health Research Center Changzhou Children's Hospital Changzhou 213003 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunpin","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Children's Health Research Center Changzhou Children's Hospital Changzhou 213003 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aibin","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Children's Health Research Center Changzhou Children's Hospital Changzhou 213003 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,7,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12264-013-1353-8"},{"key":"e_1_2_8_3_1","first-page":"3598","article-title":"Complex network analysis of resting\u2010state fMRI of the brain","volume":"2016","author":"Anwar A.R.","year":"2016","journal-title":"Conf. 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