{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T15:38:30Z","timestamp":1790005110921,"version":"4.0.1"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100011929","name":"Programa Operacional Tem\u00e1tico Factores de Competitividade","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011929","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["SFRH\/BPD\/77486\/2011"],"award-info":[{"award-number":["SFRH\/BPD\/77486\/2011"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003381","name":"Minist\u00e9rio da Educa\u00e7\u00e3o e Ci\u00eancia","doi-asserted-by":"publisher","award":["UID\/MULTI\/00211\/2013"],"award-info":[{"award-number":["UID\/MULTI\/00211\/2013"]}],"id":[{"id":"10.13039\/501100003381","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004895","name":"European Social Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Food Microbiology"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1016\/j.ijfoodmicro.2019.02.006","type":"journal-article","created":{"date-parts":[[2019,2,10]],"date-time":"2019-02-10T14:43:39Z","timestamp":1549809819000},"page":"37-42","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"special_numbering":"C","title":["Revealing mcr-1-positive ESBL-producing Escherichia coli strains among Enterobacteriaceae from food-producing animals (bovine, swine and poultry) and meat (bovine and swine), Portugal, 2010\u20132015"],"prefix":"10.1016","volume":"296","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2064-2046","authenticated-orcid":false,"given":"Lurdes","family":"Clemente","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7729-4199","authenticated-orcid":false,"given":"Vera","family":"Manageiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivone","family":"Correia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Amaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Albuquerque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia","family":"Themudo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eug\u00e9nia","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Cani\u00e7a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0005","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.3389\/fmicb.2018.01217","article-title":"Molecular epidemiology of mcr-encoded colistin resistance in Enterobacteriaceae from food-producing animals in Italy revealed through the EU harmonized antimicrobial resistance monitoring","volume":"9","author":"Alba","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0010","doi-asserted-by":"crossref","first-page":"3317","DOI":"10.1093\/jac\/dkx327","article-title":"Identification of a novel transposon-associated phosphoethanolamine transferase gene, mcr-5, conferring colistin resistance in d-tartrate fermenting Salmonella enterica subsp. enterica serovar Paratyphi B","volume":"72","author":"Borowiak","year":"2017","journal-title":"J. Antimicrob. Chemother."},{"issue":"26","key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0015","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2016.21.26.30270","article-title":"MCR-1 multidrug-resistant and copper-tolerant clinically relevant Salmonella 1,4,[5],12:- and Rissen clones in Portugal, 2011 to 2015","volume":"21","author":"Campos","year":"2016","journal-title":"Euro Surveill."},{"issue":"31","key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0020","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2017.22.31.30589","article-title":"Novel plasmid-mediated colistin resistance mcr-4 gene in Salmonella and Escherichia coli, Italy 2013, Spain and Belgium, 2015 to 2016","volume":"22","author":"Carattoli","year":"2017","journal-title":"Euro Surveill."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0025","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.ijantimicag.2015.06.005","article-title":"Use of colistin-containing products within the European Union and European Economic area (EU\/EEA): development of resistance in animals and possible impact on human and animal health","volume":"46","author":"Catry","year":"2015","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0030","author":"Cavaco"},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0130","series-title":"Methods for Dilution of Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Approved Standard","author":"CLSI, Clinical and Laboratory Standards Institute","year":"2015"},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0035","author":"Dean"},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0040","doi-asserted-by":"crossref","first-page":"5612","DOI":"10.1128\/AAC.01075-16","article-title":"MCR-1.2: a new MCR variant encoded by a transferable plasmid from a colistin-resistant KPC carbapenemase-producing Klebsiella pneumoniae of sequence type 512","volume":"60","author":"Di Pilato","year":"2016","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0045","first-page":"4872","volume":"15","author":"ECDC\/EFSA\/EMA-European Center","year":"2017","journal-title":"EFSA J."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0050","first-page":"4694","article-title":"EU summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2015","volume":"15","author":"EFSA\/ECDC-European Food Safety Authority\/European Center Disease Control","year":"2017","journal-title":"EFSA J."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0055","series-title":"Updated Advice on the Use of Colistin Products in Animals within the European Union: Development of Resistance and Possible Impact on Human and Animal Health","author":"EMA\/CVMP\/CHMP","year":"2016"},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0060","series-title":"Seventh ESVAC Report","first-page":"115","article-title":"Sales of veterinary antimicrobial agents in 26 EU\/EEA countries in 2015","author":"EMA\/ESVAC (European Medical Agency, European Surveillance of Veterinary Antimicrobial Consumption)","year":"2017"},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0065","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1093\/jac\/dkw240","article-title":"Detection of an mcr-1-encoding plasmid mediated colistin resistance in Salmonella enterica from retail meat in Portugal","volume":"71","author":"Figueiredo","year":"2016","journal-title":"J. Antimicrob. Chemother."},{"issue":"10","key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0070","doi-asserted-by":"crossref","first-page":"6433","DOI":"10.1128\/AAC.01147-16","article-title":"Increasing trends in mcr-1 prevalence among extended-spectrum-beta-lactamase-producing Escherichia coli isolates from French calves despite decreasing exposure to colistin","volume":"60","author":"Haenni","year":"2016","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0075","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S1473-3099(16)00007-4","article-title":"Co-occurrence of extended spectrum \u03b2-lactamase and MCR-1-encoding genes on plasmids","volume":"16","author":"Haenni","year":"2016","journal-title":"Lancet Infect. Dis."},{"issue":"31","key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0080","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2017.22.31.30586","article-title":"Co-occurrence of colistin-resistance genes MCR-1 and MCR-3 among multidrug resistant Escherichia coli isolated from cattle, Spain, September 2015","volume":"22","author":"Hern\u00e1ndez","year":"2017","journal-title":"Euro Surveill."},{"issue":"9","key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.clinmicnews.2016.04.003","article-title":"Polymyxin susceptibility testing: a cold case reopened","volume":"38","author":"Jerke","year":"2016","journal-title":"Clin. Microbiol. Newsl."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0090","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1111\/1462-2920.13021","article-title":"Influence of agricultural practice on mobile bla genes: IncI1-bearing CTX-M, SHV, CMY and TEM in Escherichia coli from intensive farming soils","volume":"18","author":"Jones-Dias","year":"2016","journal-title":"Environ. Microbiol."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0095","first-page":"1400","article-title":"Architecture of class 1, 2, and 3 integrons from Gram negative bacteria recovered among fruits and vegetables","volume":"13","author":"Jones-Dias","year":"2016","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0100","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.3201\/eid2312.170883","article-title":"High rate of MCR-1-producing Escherichia coli and Klebsiella pneumoniae among pigs, Portugal","volume":"23","author":"Kieffer","year":"2017","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0105","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1016\/j.cmi.2018.04.004","article-title":"Carbapenem-resistant Enterobacteriaceae in wildlife, food-producing, and companion animals: a systematic review","volume":"24","author":"K\u00f6ck","year":"2018","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0110","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S1473-3099(15)00424-7","article-title":"Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study","volume":"6","author":"Liu","year":"2016","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0115","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.02632-16","article-title":"MCR-1.6, a new MCR variant carried by an IncP plasmid in a colistin-resistant Salmonella enterica serovar Typhimurium isolate from a healthy individual","volume":"61","author":"Lu","year":"2017","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0120","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ijfoodmicro.2017.10.007","article-title":"New insights into resistance to colistin and third-generation cephalosporins of Escherichia coli in poultry, Portugal: novel blaCTX-M-166 and blaESAC genes","volume":"263","author":"Manageiro","year":"2017","journal-title":"Int. J. Food Microbiol."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0125","doi-asserted-by":"crossref","first-page":"762","DOI":"10.3201\/eid2404.171787","article-title":"mcr-1 in carbapenemase-producing Klebsiella pneumoniae with hospitalized patients, Portugal, 2016-2017","volume":"24","author":"Mendes","year":"2018","journal-title":"Emerg. Infect. Dis."},{"issue":"6","key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0135","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2016.21.6.30135","article-title":"Prevalence of mcr-1 in commensal Escherichia coli from French livestock, 2007 to 2014","volume":"21","author":"Perrin-Guyomard","year":"2016","journal-title":"Euro Surveill."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0140","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1128\/CMR.00064-16","article-title":"Polymyxins: antibacterial activity, susceptibility testing, and resistance mechanisms encoded by plasmids or chromosomes","volume":"30","author":"Poirel","year":"2017","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0145","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.ijantimicag.2017.03.014","article-title":"First report of an Escherichia coli strain from swine carrying an OXA-181 carbapenemase and the colistin resistance determinant MCR-1","volume":"50","author":"Pulss","year":"2017","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0150","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1089\/fpd.2012.1173","article-title":"Clonal diversity of ESBL-producing Escherichia coli in pigs at slaughter level in Portugal","volume":"10","author":"Ramos","year":"2013","journal-title":"Foodborne Pathog. Dis."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0155","first-page":"2245","article-title":"IncI1\/ST3 and IncN\/ST1 plasmids drive the spread of blaTEM-52 and blaCTX-M-1\/-32 in diverse Escherichia coli clones from different piggeries","volume":"68","author":"Rodrigues","year":"2017","journal-title":"J. Antimicrob. Chemother."},{"issue":"31","key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0160","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2017.22.31.30584","article-title":"Novel mcr-3 variant, encoding mobile colistin resistance, in an ST131 Escherichia coli isolate from bloodstream infection, Denmark, 2014","volume":"22","author":"Roer","year":"2017","journal-title":"Euro Surveill."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0165","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.ijantimicag.2017.03.007","article-title":"Retrospective survey of mcr-1 and mcr-2 in German pig-fattening farms, 2011-2012","volume":"50","author":"Roschanski","year":"2017","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0170","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.ijfoodmicro.2017.06.010","article-title":"Prevalence and characterization of extended-spectrum \u03b2-lactamase (ESBL) and AmpC \u03b2-lactamase producing Enterobacteriaceae in fresh pork meat at processing level in Germany","volume":"257","author":"Schill","year":"2017","journal-title":"Int. J. Food Microbiol."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0175","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.3201\/eid2308.170162","article-title":"mcr-1 and blaKPC-3 in Escherichia coli sequence type 44 after meropenem and colistin therapy, Portugal","volume":"23","author":"Tac\u00e3o","year":"2017","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0180","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0180347","article-title":"Molecular characteristics of mcr-1-carrying plasmids and new mcr-1 variant recovered from polyclonal clinical Escherichia coli from Argentina and Canada","volume":"12","author":"Tijet","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0185","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/s10096-017-3140-3","article-title":"Evaluation of colistin stability in agar and comparison of four methods for MIC testing of colistin","volume":"37","author":"Turlej-Rogacka","year":"2018","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"issue":"122","key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0190","article-title":"Emergence of a novel mobile colistin resistance gene, mcr-8, in NDM-producing Klebsiella pneumoniae","volume":"7","author":"Wang","year":"2018","journal-title":"Emerg. Microbes Infect."},{"issue":"27","key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0195","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2016.21.27.30280","article-title":"Identification of a novel plasmid-mediated colistin-resistance gene, mcr-2, in Escherichia coli, Belgium","volume":"21","author":"Xavier","year":"2016","journal-title":"Euro Surveill."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0200","doi-asserted-by":"crossref","first-page":"e01204","DOI":"10.1128\/AAC.01204-16","article-title":"Colistin resistance gene mcr-1 and its variant in Escherichia coli isolates from chickens in China","volume":"61","author":"Yang","year":"2017","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0205","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1093\/jac\/dky111","article-title":"Novel plasmid-mediated colistin resistance gene mcr-7.1 in Klebsiella pneumoniae","volume":"73","author":"Yang","year":"2018","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0210","article-title":"Novel plasmid-mediated colistin resistance gene mcr-3 in Escherichia coli","volume":"8","author":"Yin","year":"2017","journal-title":"MBio"},{"key":"10.1016\/j.ijfoodmicro.2019.02.006_bb0215","doi-asserted-by":"crossref","first-page":"3705","DOI":"10.1038\/s41598-018-22084-4","article-title":"Molecular detection of colistin resistance genes (mcr-1, mcr-2 and mcr-3) in nasal\/oropharyngeal and anal\/cloacal swabs from pigs and poultry","volume":"27","author":"Zhang","year":"2018","journal-title":"Sci. Rep."}],"container-title":["International Journal of Food Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168160518303970?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168160518303970?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T12:13:01Z","timestamp":1759147981000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168160518303970"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":43,"alternative-id":["S0168160518303970"],"URL":"https:\/\/doi.org\/10.1016\/j.ijfoodmicro.2019.02.006","relation":{},"ISSN":["0168-1605"],"issn-type":[{"value":"0168-1605","type":"print"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Revealing mcr-1-positive ESBL-producing Escherichia coli strains among Enterobacteriaceae from food-producing animals (bovine, swine and poultry) and meat (bovine and swine), Portugal, 2010\u20132015","name":"articletitle","label":"Article Title"},{"value":"International Journal of Food Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijfoodmicro.2019.02.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}