{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T01:31:01Z","timestamp":1793496661796,"version":"4.5.0"},"reference-count":15,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["international-journal-of-gynecological-cancer.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Gynecological Cancer"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.ijgc.2025.102650","type":"journal-article","created":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T15:00:51Z","timestamp":1757084451000},"page":"102650","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Long-term oral contraceptive use as a risk factor for high-grade cervical lesions in women with high-risk human papillomavirus: a retrospective cohort analysis"],"prefix":"10.1016","volume":"35","author":[{"given":"Farah","family":"Farzaneh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Dastyar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marzieh","family":"Mohammadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam Sadat","family":"Hosseini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Soltani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ijgc.2025.102650_bib1","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1097\/01.ogx.0000931688.91347.0a","article-title":"Human papillomavirus vaccination and cervical cancer risk","volume":"78","author":"Rahangdale","year":"2023","journal-title":"Obstet Gynecol Surv"},{"key":"10.1016\/j.ijgc.2025.102650_bib2","unstructured":"van Eer K. The human papillomavirus: dynamics between vaccination, viral properties and surveillance. Vrije Universiteit Amsterdam. Accessed September 24, 2025. https:\/\/research.vu.nl\/en\/publications\/the-human-papillomavirus-dynamics-between-vaccination-viral-prope."},{"key":"10.1016\/j.ijgc.2025.102650_bib3","unstructured":"Bleotu C, Anton G. The indicators of predicting disease outcome in HPV carcinogenesis. InTech. Accessed September 24, 2025. https:\/\/www.intechopen.com\/chapters\/30748."},{"issue":"12","key":"10.1016\/j.ijgc.2025.102650_bib4","doi-asserted-by":"crossref","first-page":"e818","DOI":"10.1055\/s-0043-1776403","article-title":"Combined oral contraceptive use and the risk of cervical cancer: literature review","volume":"45","author":"Bovo","year":"2023","journal-title":"Rev Bras Ginecol Obstet."},{"issue":"2","key":"10.1016\/j.ijgc.2025.102650_bib5","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1080\/17512433.2020.1721280","article-title":"Pharmacodynamics of combined estrogen-progestin oral contraceptives: 4. Effects on uterine and cervical epithelia","volume":"13","author":"Bastianelli","year":"2020","journal-title":"Expert Rev Clin Pharmacol"},{"issue":"12","key":"10.1016\/j.ijgc.2025.102650_bib6","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1016\/j.ajpath.2019.08.013","article-title":"Medroxyprogesterone acetate prevention of cervical cancer through progesterone receptor in a human papillomavirus transgenic mouse model","volume":"189","author":"Baik","year":"2019","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ijgc.2025.102650_bib7","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.918190","article-title":"The association of cervicovaginal Langerhans cells with clearance of human papillomavirus","volume":"13","author":"Dai","year":"2022","journal-title":"Front Immunol"},{"issue":"10","key":"10.1016\/j.ijgc.2025.102650_bib8","doi-asserted-by":"crossref","first-page":"3047","DOI":"10.1016\/j.celrep.2019.10.118","article-title":"Langerhans cells orchestrate the protective antiviral innate immune response in the lymph node","volume":"29","author":"Wong","year":"2019","journal-title":"Cell Rep"},{"issue":"1","key":"10.1016\/j.ijgc.2025.102650_bib9","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1186\/s12935-019-0935-6","article-title":"Interaction between 17\u03b2-estradiol, prolactin and human papillomavirus induce E6\/E7 transcript and modulate the expression and localization of hormonal receptors","volume":"19","author":"Ram\u00edrez-L\u00f3pez","year":"2019","journal-title":"Cancer Cell Int"},{"key":"10.1016\/j.ijgc.2025.102650_bib10","unstructured":"Greer AC, Lowey CA. Visualizing the degradation of pRb by the high-risk HPV protein E7. Wesleyan-Holiness Digital Library. Accessed September 24, 2025. https:\/\/www.whdl.org\/en\/browse\/resources\/12627."},{"key":"10.1016\/j.ijgc.2025.102650_bib11","unstructured":"Gill SS, Jana AM, Shrivastav A, Sharma S, Sharma A. The carcinogenic potential of E6 & E7 genes of high-risk HPV compared with E6, E7 genes of low-risk HPV in human cervical cancer: a review. International Journal of Pharmaceutical Sciences and Research. Accessed September 24, 2025. https:\/\/ijpsr.com\/bft-article\/the-carcinogenic-potential-of-e6-e7-genes-of-high-risk-hpv-compared-with-e6-e7-genes-of-low-risk-hpv-in-human-cervical-cancer-a-review\/?view=fulltext."},{"issue":"11","key":"10.1016\/j.ijgc.2025.102650_bib12","doi-asserted-by":"crossref","first-page":"5995","DOI":"10.21873\/anticanres.14620","article-title":"Estro-progestin contraceptives and risk of cervical cancer: a debated issue","volume":"40","author":"Gadducci","year":"2020","journal-title":"Anticancer Res"},{"issue":"7","key":"10.1016\/j.ijgc.2025.102650_bib13","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1248\/bpb.b19-01098","article-title":"Evidence of passive smoking as a risk factor of high-grade squamous intraepithelial lesion: a case-control study","volume":"43","author":"Du","year":"2020","journal-title":"Biol Pharm Bull"},{"issue":"9599","key":"10.1016\/j.ijgc.2025.102650_bib14","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1016\/S0140-6736(07)61684-5","article-title":"Cervical cancer and hormonal contraceptives: collaborative reanalysis of individual data for 16,573 women with cervical cancer and 35,509 women without cervical cancer from 24 epidemiological studies","volume":"370","author":"Appleby","year":"2007","journal-title":"Lancet"},{"issue":"suppl 13","key":"10.1016\/j.ijgc.2025.102650_bib15","doi-asserted-by":"crossref","first-page":"2202","DOI":"10.1158\/1538-7445.AM2018-2202","article-title":"Abstract 2202: Long term risk prediction of p16\/Ki-67 dual stain in triage of HPV-positive women","volume":"78","author":"Clarke","year":"2018","journal-title":"Cancer Research"}],"container-title":["International Journal of Gynecological Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1048891X25017700?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1048891X25017700?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T01:27:02Z","timestamp":1793496422000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1048891X25017700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":15,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["S1048891X25017700"],"URL":"https:\/\/doi.org\/10.1016\/j.ijgc.2025.102650","relation":{},"ISSN":["1048-891X"],"issn-type":[{"value":"1048-891X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-term oral contraceptive use as a risk factor for high-grade cervical lesions in women with high-risk human papillomavirus: a retrospective cohort analysis","name":"articletitle","label":"Article Title"},{"value":"International Journal of Gynecological Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijgc.2025.102650","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 European Society of Gynaecological Oncology and the International Gynecologic Cancer Society. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"102650"}}