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This article reviews technical issues related to diagnosis, screening, prevention, and treatment of pre\u2010eclampsia and identifies corresponding needs. The authors stress the lack of standardized definitions of pre\u2010eclampsia and eclampsia and discuss problems in blood\u2010pressure measurements and assessment of urinary protein. They summarize the evidence for prevention strategies and screening tests for early detection. For treatment, magnesium sulfate has been proven effective, but not widely used. The authors outline priorities for narrowing the identified gaps and emphasize the need for coordinated efforts to reduce the morbidity and mortality due to pre\u2010eclampsia\/eclampsia. 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