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Fetal lung maturity was detected by amniocentesis and blood samples for umbilical blood gas analysis (UBGA) were collected before the first neonatal breath from the umbilical artery in a double\u2010clamped segment of the cord. <jats:italic>Results<\/jats:italic>: Umbilical cord gas analysis showed arterial cord blood pH to be 7.20 or less in 11 newborns (45.8%), 7.10 or less in 6 (25%), and 7.00 or less in 3 (12.5%). Linear regression analysis showed short\u2010term variation (STV) in the fetal heart rate to be significantly correlated with umbilical artery pH (<jats:italic>r<\/jats:italic>=0.49; <jats:italic>P<\/jats:italic>=0.01) and pCO<jats:sub>2<\/jats:sub> (<jats:italic>r<\/jats:italic>=\u22120.50; <jats:italic>P<\/jats:italic>=0.01). There were no significant correlations between cCTG and the other UBGA parameters considered. Receiver operator curves permitted to calculate the STV values at which pathological neonatal UBGA values can be expected (pH&lt;7.00 and pCO<jats:sub>2<\/jats:sub>&gt;80 mmHg). A short\u2010term variation less than 4.5 ms was found to predict acidemia with a sensitivity of 100% and a specificity of 70% (positive predictive value, 33%; negative predictive value, 100%), and hypercarbia with a sensitivity of 100% and a specificity of 77.8% (positive predictive value, 55.6%; negative predictive value, 100%). <jats:italic>Conclusion<\/jats:italic>: In view of the results of this study, 4.5 ms for STV may be a threshold below which timing of delivery should be decided in cases of fetal growth restriction.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2004.05.012","type":"journal-article","created":{"date-parts":[[2004,8,10]],"date-time":"2004-08-10T19:55:27Z","timestamp":1092167727000},"page":"365-370","source":"Crossref","is-referenced-by-count":41,"title":["Computerized cardiotocography in the management of intrauterine growth restriction associated with Doppler velocimetry alterations"],"prefix":"10.1002","volume":"86","author":[{"given":"M.M.","family":"Anceschi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Ruozi\u2010Berretta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.J.","family":"Piazze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Cosmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Cerekja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Meloni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.V.","family":"Cosmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,8,6]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"325","article-title":"A population study of the relationship between fetal death and altered fetal growth","volume":"74","author":"Myers S.A.","year":"1989","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-199702000-00023"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1980.tb04498.x"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(89)90497-3"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1995.06030168.x"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1991.01030192.x"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70316-9"},{"key":"e_1_2_6_9_2","first-page":"1103","article-title":"Pathological fetal acidemia","volume":"78","author":"Goldaber K.G.D.","year":"1991","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_10_2","unstructured":"American College of Obstetricians and Gynecologists. 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