{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T04:52:15Z","timestamp":1771476735916,"version":"3.50.1"},"reference-count":7,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,9,17]],"date-time":"2004-09-17T00:00:00Z","timestamp":1095379200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2004,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p><jats:italic>Objective:<\/jats:italic> To compare the efficacy of two routes of misoprostol administration (oral and vaginal) for treatment of missed abortion. <jats:italic>Methods:<\/jats:italic>Two hundred women with confirmed missed abortion received 800 mcg misoprostol either orally or vaginally. All women returned for follow\u2010up care 2 days later. If the pregnancy was not completely evacuated at this time, women could wait an additional 5 days or undergo immediate surgical completion. Efficacy was defined as the percent of women discharged from the study without need for surgical intervention. <jats:italic>Results:<\/jats:italic>Efficacy was high in both groups and not statistically different (oral=89.0%, vaginal=92.9%). While the groups did not differ in terms of the completion rate by day 2 (oral=41.6%, vaginal=52.7%), the mean time to expulsion was longer (21.04 h) in the oral group than the vaginal group (13.47 h), <jats:italic>p<\/jats:italic>=0.041. Women in both groups were highly satisfied with the method. <jats:italic>Conclusions:<\/jats:italic>Medical management of missed abortion with either oral or vaginal misoprostol is highly effective and highly acceptable.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2004.07.015","type":"journal-article","created":{"date-parts":[[2004,9,21]],"date-time":"2004-09-21T18:24:21Z","timestamp":1095791061000},"page":"138-142","source":"Crossref","is-referenced-by-count":46,"title":["Medical treatment of missed abortion using misoprostol"],"prefix":"10.1002","volume":"87","author":[{"given":"N.T.N.","family":"Ngoc","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Blum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Westheimer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.T.V.","family":"Quan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Winikoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,9,17]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"105","article-title":"Spontaneous abortion","volume":"13","author":"Laferla JJ.","year":"1986","journal-title":"Clin. 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