{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T20:16:44Z","timestamp":1771013804633,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,7,26]],"date-time":"2005-07-26T00:00:00Z","timestamp":1122336000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2005,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p><jats:italic>Objective:<\/jats:italic> To determine whether management of incomplete first\u2010trimester abortion with vaginal misoprostol in an under\u2010resourced setting is a viable treatment option. <jats:italic>Methods:<\/jats:italic> A total of 94 women were randomized to 600 \u03bcg of misoprostol intravaginally or to surgical curettage. The women receiving misoprostol were administered a second dose if the abortion was incomplete; and if still not complete after a week, evacuation of retained products of conception was performed. All women had a follow\u2010up visit 2 weeks following complete abortion. <jats:italic>Results:<\/jats:italic> The overall success rate of medical management was 91.5%, with 15 of 47 successful cases after 1 dose of misoprostol; 8.5% of the 47 women required evacuation of retained products of conception after 1 week because of treatment failure. The success rate in the surgical arm was 100%. Patients in the medical arm had a longer duration of bleeding and a greater need for analgesia. There were no differences in hemoglobin levels, white blood cell count, adverse effects, pain score, and satisfaction with treatment at the follow\u2010up visit. However, more women who received the medical treatment would recommend it or choose it in the future. <jats:italic>Conclusion:<\/jats:italic> Medical management using 600 \u03bcg of misoprostol in 2 doses is effective to treat incomplete first\u2010trimester abortions in an under\u2010resourced setting when there is no evidence of uterine sepsis.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2005.06.009","type":"journal-article","created":{"date-parts":[[2005,7,28]],"date-time":"2005-07-28T21:24:29Z","timestamp":1122585869000},"page":"21-26","source":"Crossref","is-referenced-by-count":27,"title":["Medical vs. surgical evacuation of first\u2010trimester spontaneous abortion"],"prefix":"10.1002","volume":"91","author":[{"given":"S.","family":"Moodliar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.S.","family":"Bagratee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Moodley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,7,26]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"69","article-title":"A comparative study of incomplete miscarriages at San Francisco Hospital","volume":"11","author":"Hartman J.W.","year":"1953","journal-title":"Stanf Med Bull"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-200102000-00024"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(82)80256-4"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(86)90082-7"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh049"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/ejc.6.3.141.144"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/16.7.1493"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-0528.2003.t01-1-02036.x"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)90060-8"},{"key":"e_1_2_5_11_2","first-page":"670","article-title":"Expectant management of early pregnancy failure","volume":"105","author":"Jurkorvic D.","year":"1998","journal-title":"Br J Obstet Gynaecol"},{"key":"e_1_2_5_12_2","first-page":"438","article-title":"Management of incomplete miscarriages in South African public hospitals","volume":"87","author":"Fawcus S.","year":"1997","journal-title":"S Afr Med J"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/16.2.365"},{"key":"e_1_2_5_14_2","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1093\/oxfordjournals.humrep.a135965","article-title":"Induction of labour in the second trimester by a combination of misoprostol and mifepristone: a randomized comparison between two misoprostol regimes","volume":"10","author":"El Refaey H.","year":"1995","journal-title":"Hum Reprod"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.311.7006.662"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2003.03115.x"},{"key":"e_1_2_5_17_2","first-page":"CD002855","article-title":"Medical methods for first trimester miscarriage","volume":"2","author":"Kulier R.","year":"2004","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/16.11.2283"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00111-7"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2003.07.004"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(98)70147-4"}],"container-title":["International Journal of Gynecology &amp; 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