{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T09:01:17Z","timestamp":1790586077479,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,6,12]],"date-time":"2006-06-12T00:00:00Z","timestamp":1150070400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2006,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective<\/jats:italic>: Vaginal deliveries have been associated with pelvic organ prolapse and incontinence. The objective was to show whether markers of ischemia\/reperfusion injury are dependent upon the mode of delivery and length of labor. <jats:italic>Method<\/jats:italic>: Complete venipuncture sets were obtained on 62 subjects. All samples collected were analyzed for serum creatine phosphokinase (CPK) and lactate dehydrogenase (LDH). Lipid peroxidation was analyzed, using thiobarbituric acid reactive substances (TBARS), on a subset of 37 patients. <jats:italic>Results<\/jats:italic>: There was a significant increase in CPK from admission to 1\u00a0h postpartum and postpartum day 1 in vaginal delivery versus cesarean delivery. Longer second stages were associated with significant increases in CPK. There were no significant changes in either LDH or TBARS from admission to any other time point regardless of mode of delivery. <jats:italic>Conclusion<\/jats:italic>: Vaginal delivery and longer second stages were associated with a much greater increase in one of these injury markers.<\/jats:p>","DOI":"10.1016\/j.ijgo.2006.04.039","type":"journal-article","created":{"date-parts":[[2006,6,13]],"date-time":"2006-06-13T14:20:58Z","timestamp":1150208458000},"page":"96-102","source":"Crossref","is-referenced-by-count":17,"title":["Vaginal delivery and serum markers of ischemia\/reperfusion injury"],"prefix":"10.1002","volume":"94","author":[{"given":"E.","family":"Conner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Margulies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengling","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.W.","family":"Smilen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.F.","family":"Porges","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,6,12]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(96)00151-2"},{"key":"e_1_2_5_3_2","first-page":"46","article-title":"The appearance of levator ani muscle abnormalities in magnetic resonance images after vaginal delivery","volume":"101","author":"Delancy J.O.","year":"2003","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(97)89593-1"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1053\/ejvs.2002.1614"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2003.65"},{"key":"e_1_2_5_7_2","first-page":"58","article-title":"Accentuated oxidative stress following reperfusion injury in diabetic rats","volume":"21","author":"Edrees W.K.","year":"2002","journal-title":"Int Angiol"},{"key":"e_1_2_5_8_2","first-page":"281","article-title":"The role of nickel and nickel\u2010mediated reactive oxygen species in the mechanism of nickel carcinogenesis","volume":"102","author":"Huang X.","year":"1994","journal-title":"Molec Mech of Metal Tox Carc"},{"key":"e_1_2_5_9_2","first-page":"693","article-title":"\u03b1\u2010tocopherol and iloprost attenuate reperfusion injury in skeletal muscle ishemia\/reperfusion injury","volume":"43","author":"Bozkurt A.K.","year":"2002","journal-title":"J Cardiovasc Surg"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.3109\/17453679909011264"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/micr.21733"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(20)90067-4"},{"key":"e_1_2_5_13_2","first-page":"72","article-title":"Prevention of childbirth injuries to the pelvic floor","volume":"1","author":"Heit M.","year":"2001","journal-title":"Curr Womens Health Rep"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-4804(03)00094-5"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1006\/jsre.2000.5823"}],"container-title":["International Journal of Gynecology &amp; 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