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Unpublished data previously presented at international scientific meetings were also included in the review. Little evidence exists in support of misoprostol for treatment of postpartum hemorrhage (PPH). Nonetheless, PPH remains a major killer of women worldwide, and new treatment options are widely sought. For this reason, we recommend a single dose of misoprostol 600\u00a0\u03bcg oral or sublingual for PPH treatment in instances when other treatments have either failed to work or are not available.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2007.09.013","type":"journal-article","created":{"date-parts":[[2007,10,26]],"date-time":"2007-10-26T09:58:26Z","timestamp":1193392706000},"source":"Crossref","is-referenced-by-count":20,"title":["Treatment of postpartum hemorrhage with misoprostol"],"prefix":"10.1002","volume":"99","author":[{"given":"J.","family":"Blum","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.","family":"Alfirevic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Walraven","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Weeks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Winikoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,10,24]]},"reference":[{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-200112000-00008"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)32308-8"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016348909028674"},{"key":"e_1_2_9_5_2","first-page":"665","article-title":"Intramyometrial prostaglandin F2 alpha in the treatment of severe postpartum hemorrhage","volume":"55","author":"Jacobs M.M.","year":"1980","journal-title":"Obstet Gynecol"},{"issue":"6","key":"e_1_2_9_6_2","first-page":"47S","article-title":"Control of postpartum uterine atony by intramyometrial prostaglandin","volume":"59","author":"Bruce S.L.","year":"1982","journal-title":"Obstet Gynecol"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1990.tb14569.x"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03005350"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.1998.770513.x"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(98)00161-6"},{"key":"e_1_2_9_11_2","first-page":"221","article-title":"Misoprostol in uterine atony: a report of 2 cases","volume":"27","author":"Ozan H.","year":"2000","journal-title":"Clin Exp Obstet Gynecol"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(00)00321-0"},{"key":"e_1_2_9_13_2","first-page":"572","article-title":"Rectal administration of misoprostol for delivery induced hemorrhage. 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