{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T11:00:37Z","timestamp":1760266837636},"reference-count":11,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2008,1,28]],"date-time":"2008-01-28T00:00:00Z","timestamp":1201478400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2008,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To ascertain the impact of long referral to first colposcopy interval on disease outcome in women with high\u2010grade cervical smear tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from 316 women categorized into Group 1 (seen 180 days after referral) and Group 2 (seen within 180 days of referral) were analyzed using <jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup> test with Yates correction. Odds ratios (OR) and 95% confidence intervals (CI) were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Women in Group 1 were less likely to need treatment (33.8% [25\/74] vs 55.8% [135\/242]; OR = 0.45; 95% CI, 0.25\u20130.78; <jats:italic>P<\/jats:italic> = 0.0004) and less likely to have high\u2010grade disease (24.3% [18\/74] vs 45.9% [111\/242]); OR = 0.37; 95% CI, 0.21\u20130.68; <jats:italic>P<\/jats:italic> = 0.001) than women in Group 2. There was no significant difference between the groups in proportion of women with invasive disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In women with high\u2010grade smears the need for excisional treatment and the risk of invasive disease may be reduced by prolonged referral interval.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2007.11.014","type":"journal-article","created":{"date-parts":[[2008,1,30]],"date-time":"2008-01-30T14:46:38Z","timestamp":1201704398000},"page":"245-247","source":"Crossref","is-referenced-by-count":4,"title":["Impact of prolonged referral interval on colposcopic outcomes in women with moderate or severe dysplasia"],"prefix":"10.1002","volume":"101","author":[{"given":"Biodun","family":"Fakokunde","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Selo\u2010Ojeme","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,1,28]]},"reference":[{"key":"e_1_2_5_2_2","volume-title":"Colposcopy and Programme Management: Guidelines for the NHS Cervical Screening Programme","author":"NHS Cancer Screening Programmes","year":"2004"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68181-6"},{"issue":"4","key":"e_1_2_5_4_2","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/S0029-7844(98)00245-2","article-title":"Natural history of cervical squamous intraepithelial lesions: a meta\u2010analysis","volume":"92","author":"Melnikow J.","year":"1998","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1986.tb07816.x"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.308.6941.1421"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)91746-W"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1994.1107"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1999.tb08082.x"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.301.6753.641"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)90278-B"},{"key":"e_1_2_5_12_2","unstructured":"Colposcopy Annual Results 2005\u20132006. 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