{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:27:41Z","timestamp":1762100861084,"version":"3.28.0"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,10,11]],"date-time":"2008-10-11T00:00:00Z","timestamp":1223683200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2009,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate the association between intercellular adhesion molecule\u20101 (ICAM\u20101) gene K469E polymorphism and spontaneous preterm delivery in a Korean population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Genomic DNA was extracted from whole blood from 55 women experiencing preterm labor and 153 multiparous women (control group) with a history of at least 2 term deliveries. DNA samples were analyzed by polymerase chain reaction\u2013restriction fragment length polymorphism.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The spontaneous preterm delivery (SPD) group carried the 469E allele significantly more frequently than those in the control group (odds ratio [OR], 1.62; 95% CI, 1.04\u20132.53). The EE genotype was significantly associated with increased risk of SPD (OR, 2.84; 95% CI, 1.17\u20136.89; <jats:italic>P<\/jats:italic> = 0.02). Allelic frequencies in women with abnormal C\u2010reactive protein levels (K = 0.48; E = 0.52) were significantly different from frequencies in the controls (K = 0.68; E = 0.32) (<jats:italic>P<\/jats:italic> = 0.006).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>ICAM\u20101 gene K469E polymorphism may be a candidate region and useful predictor of susceptibility to SPD in the Korean population.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2008.08.020","type":"journal-article","created":{"date-parts":[[2008,10,15]],"date-time":"2008-10-15T01:48:06Z","timestamp":1224035286000},"page":"37-39","source":"Crossref","is-referenced-by-count":7,"title":["Intercellular adhesion molecule\u20101 K469E polymorphism in Korean patients with spontaneous preterm delivery"],"prefix":"10.1002","volume":"104","author":[{"given":"Han\u2010Sung","family":"Kwon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In\u2010Sook","family":"Sohn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji\u2010Young","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun\u2010Joo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo\u2010Nyung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bok\u2010Ja","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,10,11]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2006.01120.x"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(95)90331-3"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2003.11.009"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2370.2000.00202.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2006.01948.x"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70273-4"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2006.09.002"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.122407"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-0528.2003.00024.x-i1"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.04.021"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1006\/cyto.1998.0382"},{"issue":"5","key":"e_1_2_6_13_2","first-page":"671","article-title":"Serum intercellular adhesion molecule\u20101 levels and histologic chorioamnionitis","volume":"95","author":"Steinborn A.","year":"2000","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1071\/RD99066"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5201033"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1999.00427.x"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.2004.00285.x"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2003.18.3.415"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1999.00427.x"},{"issue":"3","key":"e_1_2_6_20_2","first-page":"502","article-title":"Intercellular adhesion molecule\u20101 gene polymorphisms in isolated polymyalgia rheumatica","volume":"29","author":"Amoli M.M.","year":"2002","journal-title":"J Rheumatol"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.52.1.75"},{"issue":"4","key":"e_1_2_6_22_2","first-page":"509","article-title":"Characteristics of women in preterm labor associated with elevated C\u2010reactive protein levels","volume":"82","author":"Watts D.H.","year":"1993","journal-title":"Obstet Gynecol"}],"container-title":["International Journal of Gynecology &amp; 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