{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T17:33:43Z","timestamp":1773077623510,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2008,10,28]],"date-time":"2008-10-28T00:00:00Z","timestamp":1225152000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2009,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the effectiveness and safety of loop electrosurgical excision procedure (LEEP) to treat cervical intraepithelial neoplasia (CIN) in rural India.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Women with CIN colposcopic features unsuitable for cryotherapy were treated with LEEP using a \u201csee\u2010and\u2010treat\u201d approach. Women with unsatisfactory colposcopy had diagnostic LEEP. Cure was defined as no clinical or histologic evidence of CIN at 1\u2010year follow\u2010up. Factors influencing cure rates were evaluated by \u03c7<jats:sup>2<\/jats:sup> tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 1141 women who underwent LEEP (569 see\u2010and\u2010treat; 572 unsatisfactory colposcopy), 634 had histologically proven CIN. Of those, 489 reported for follow\u2010up and 459 (93.9%) had no evidence of disease. Cure rates were 98.1% for women with CIN 1, 93.6% for CIN 2, and 85.0% for CIN 3. Patients with CIN 2\u20133 had significantly lower cure rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cure rates for LEEP provided by newly trained doctors in rural India were similar to those reported in the gynecological literature.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2008.09.009","type":"journal-article","created":{"date-parts":[[2008,10,29]],"date-time":"2008-10-29T08:13:39Z","timestamp":1225268019000},"page":"95-99","source":"Crossref","is-referenced-by-count":13,"title":["Effectiveness and safety of loop electrosurgical excision procedure for cervical neoplasia in rural 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