{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T15:52:28Z","timestamp":1781106748273,"version":"3.54.1"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2008,12,5]],"date-time":"2008-12-05T00:00:00Z","timestamp":1228435200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2009,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the recurrence rates of cervical intraepithelial neoplasia (CIN) in a cohort of HIV\u2010infected and noninfected women who underwent the loop electrosurgical excision procedure (LEEP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective cohort study of 94 HIV\u2010positive and 107 HIV\u2010negative women, both with CIN, treated with LEEP. The diagnosis of recurrence was established after biopsy. The Kaplan\u2010Meier method was used for survival analysis and multivariate analyses were carried out using the Cox proportional hazards regression model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a predominance of low\u2010grade lesions in HIV\u2010positive compared with HIV\u2010negative women (<jats:italic>P<\/jats:italic> &lt; 0.01). Recurrence was more frequent with compromised margins and glandular involvement (<jats:italic>P<\/jats:italic> &lt; 0.01). A multivariate analysis showed that HIV\u2010infection, glandular involvement, and positive margins were independently associated with recurrence of lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Recurrence rate of CIN in HIV\u2010positive women was higher than in HIV\u2010negative women. The factors associated with recurrence were HIV infection, glandular involvement, and positive margins.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2008.10.009","type":"journal-article","created":{"date-parts":[[2008,12,6]],"date-time":"2008-12-06T09:24:02Z","timestamp":1228555442000},"page":"100-104","source":"Crossref","is-referenced-by-count":39,"title":["Cervical intraepithelial neoplasia recurrence after conization in HIV\u2010positive and HIV\u2010negative women"],"prefix":"10.1002","volume":"104","author":[{"given":"Maria In\u00eas","family":"Lima","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Tafuri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela C","family":"Ara\u00fajo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiza","family":"de Miranda Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor Hugo","family":"Melo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,12,5]]},"reference":[{"key":"e_1_2_5_2_2","unstructured":"Minist\u00e9rio da Sa\u00fade. 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