{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:59:19Z","timestamp":1760983159122},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2009,9,3]],"date-time":"2009-09-03T00:00:00Z","timestamp":1251936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To explore whether a single\u2010step diagnosis and treatment of premalignant cervical lesions by the loop electrosurgical excision procedure (LEEP) is appropriate in women at high risk in low\u2010resource countries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Sixty women suspected of having a high\u2010grade lesion on both visual inspection with acetic acid (VIA) and colposcopic examination were randomly allotted to one of 2 groups. In group 1, LEEP was performed immediately and a tissue specimen was sent for histopathologic evaluation; in group 2, a punch biopsy was performed, followed by a histopathologic evaluation; then, LEEP was performed if needed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the patients who underwent LEEP, 4 (16%) in group 1 and 3 (15.8%) in group 2 were overtreated. No patients dropped out of the study in group 1 but 5 (20.8%) did in group 2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The single\u2010step diagnosis and LEEP treatment of premalignant cervical lesions is appropriate in low\u2010resource countries.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2009.07.027","type":"journal-article","created":{"date-parts":[[2009,9,4]],"date-time":"2009-09-04T10:33:00Z","timestamp":1252060380000},"page":"224-227","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of a single\u2010step diagnosis and treatment of premalignant cervical lesion by LEEP"],"prefix":"10.1002","volume":"107","author":[{"given":"Mohamed","family":"Emam","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aboubakr","family":"Elnashar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hesham","family":"Shalan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafik","family":"Barakat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,9,3]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.46.1.5"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-199604000-00021"},{"issue":"3","key":"e_1_2_6_4_2","first-page":"S5367","article-title":"Early detection of cervical cancer with visual inspection methods","volume":"45","author":"Franco E.l.","year":"2003","journal-title":"SALUD Publica Mex"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1438.2003.13394.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.1991.tb00024.x"},{"key":"e_1_2_6_7_2","volume-title":"Colposcopy and Programme Management: Guidelines for the NHS Cervical Screening Programme","author":"Luesley D.","year":"2004"},{"key":"e_1_2_6_8_2","unstructured":"American Society for Colposcopy and Cervical Pathology. 2006 Consensus Guidelines for the Management of Women with Abnormal Cervical Cancer Screening Tests.http:\/\/www.asccp.org\/consensus\/cytological.shtml."},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(98)00042-3"},{"key":"e_1_2_6_10_2","volume-title":"Large loop excision of the transformation zone","author":"Prendiville W.","year":"1993"},{"key":"e_1_2_6_11_2","first-page":"93","article-title":"Potential complications of loop excision","volume":"39","author":"Baggish M.S.","year":"1994","journal-title":"Contemp Ob\/Gyn"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2005.02.008"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2004.09.018"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2004.12.040"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2006.01.024"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-132-10-200005160-00009"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1991.tb10376.x"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2006.00344.x"},{"issue":"2","key":"e_1_2_6_19_2","first-page":"76","article-title":"Complications of outpatient LLETZ procedures","volume":"49","author":"Dunn T.S.","year":"2004","journal-title":"J Reprod Med"},{"key":"e_1_2_6_20_2","first-page":"337","article-title":"Electrosurgical loop excision of the cervical transformation zone: the experience of family physicians","volume":"4194","author":"Ferris D.G.","year":"1995","journal-title":"J Fam Pract"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/00128360-200501000-00002"},{"issue":"3","key":"e_1_2_6_22_2","first-page":"253","article-title":"'See and treat' electrosurgical loop excision of the cervical transformation zone","volume":"42","author":"Ferris D.G.","year":"1996","journal-title":"J Fam Pract"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2005.12.025"},{"issue":"10","key":"e_1_2_6_24_2","first-page":"1025","article-title":"Follow\u2010up after LLETZ: could schedules be modified according to risk of recurrence?","volume":"108","author":"Flannelly G.","year":"2001","journal-title":"BJOG"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0020729209004007?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0020729209004007?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2Fj.ijgo.2009.07.027","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2Fj.ijgo.2009.07.027","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.ijgo.2009.07.027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T11:06:13Z","timestamp":1696331173000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1016\/j.ijgo.2009.07.027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9,3]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["10.1016\/j.ijgo.2009.07.027"],"URL":"https:\/\/doi.org\/10.1016\/j.ijgo.2009.07.027","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9,3]]}}}