{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T06:10:17Z","timestamp":1692511817231},"reference-count":8,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2009,11,4]],"date-time":"2009-11-04T00:00:00Z","timestamp":1257292800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the impact of the cough technique on the tip temperature reached in a cryotherapy device commonly used to treat precancerous cervical lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>During February to March 2009, bench testing was conducted in Peru on 3 Wallach LL100 cryotherapy units using locally obtained carbon dioxide as the refrigerant. The temperature at the cryo tip was measured continuously with a thermocouple. Mean temperatures recorded with and without the cough technique were compared across the 3 cryotherapy devices.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Higher mean temperatures were observed with the cough technique (\u2212 21.7 \u00b0C [95% CI, \u2212 23.0 to \u2212 20.4]; \u2212 22.0 \u00b0C [95% CI, \u2212 24.2 to \u2212 19.7]; \u2212 29.4 \u00b0C [95% CI, \u2212 30.3 to \u2212 28.6]) compared with mean temperatures observed with the standard procedure (\u2212 38.6 \u00b0C [95% CI, \u2212 44.8 to \u2212 32.4]; \u2212 36.0 \u00b0C [95% CI, \u2212 43.5 to \u2212 28.5]; \u2212 41.4 \u00b0C [95% CI, \u2212 49.8 to \u2212 33.0]). No test performed with the cough technique reached a temperature below \u2212 33 \u00b0C.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Higher temperatures were observed when the cough technique was used. Caution should be exercised by practitioners who use this procedure when performing cryotherapy because the temperatures obtained may not be sufficient to destroy precancerous tissue.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2009.08.032","type":"journal-article","created":{"date-parts":[[2009,11,5]],"date-time":"2009-11-05T12:30:55Z","timestamp":1257424255000},"page":"115-118","source":"Crossref","is-referenced-by-count":1,"title":["Effect of the \u201ccough technique\u201d on cryotherapy freezing temperature"],"prefix":"10.1002","volume":"108","author":[{"given":"Jennifer L.","family":"Winkler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jered","family":"Singleton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlie","family":"Loesel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amynah","family":"Janmohamed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose","family":"Jeronimo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,11,4]]},"reference":[{"key":"e_1_2_7_2_2","volume-title":"GLOBOCAN 2002: Cancer Incidence, Mortality and Prevalence Worldwide IARC CancerBase No. 5. version 2.0","author":"Ferlay J.","year":"2004"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2005.01.026"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2007.07.009"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1006\/cryo.1998.2115"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6874-7-16"},{"key":"e_1_2_7_7_2","volume-title":"Cervical Cancer Prevention Guidelines for Low\u2010resource Settings","author":"Blumenthal P.D.","year":"2004"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2007.11.013"},{"key":"e_1_2_7_9_2","volume-title":"Cervical Cancer Prevention Issues in Depth No. 1","author":"Castro W.","year":"2003"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0020729209005347?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0020729209005347?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2Fj.ijgo.2009.08.032","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2Fj.ijgo.2009.08.032","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.ijgo.2009.08.032","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T05:54:38Z","timestamp":1692510878000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1016\/j.ijgo.2009.08.032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11,4]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["10.1016\/j.ijgo.2009.08.032"],"URL":"https:\/\/doi.org\/10.1016\/j.ijgo.2009.08.032","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,11,4]]}}}