{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T14:16:58Z","timestamp":1756995418703},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2010,5,15]],"date-time":"2010-05-15T00:00:00Z","timestamp":1273881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2010,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the prevalence of and predictors for underlying significant lesions in women with low\u2010grade squamous intraepithelial lesion (LSIL) smears.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Records were retrospectively reviewed for 208 women with LSIL who underwent colposcopy and histological evaluation from October 2004 through April 2009.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean age of the patients was 38.5 years. Forty\u2010four (21.2%) women were nulliparous; 20 (9.6%) women were postmenopausal; 29 (13.9%) women tested positive for HIV. Thirty\u2010three (15.9%) women were current users of combined oral contraceptive pills. The pathological results of initial colposcopic evaluations were: 63 (30.3%) with cervical intraepithelial neoplasia (CIN) 2\u20133; 62 (29.8%) with CIN 1; 4 (1.9%) with cervical cancer; and 79 (38.0%) with no epithelial lesion. Current use of combined oral contraceptive pills, a positive HIV test, and multiparity were significant independent predictors for high\u2010grade disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Approximately one\u2010third of women with LSIL in our population have underlying significant lesions. Current use of combined oral contraceptive pills, a positive HIV test, and multiparity are significant predictors for high\u2010grade lesions.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2010.03.022","type":"journal-article","created":{"date-parts":[[2010,5,17]],"date-time":"2010-05-17T08:07:37Z","timestamp":1274083657000},"page":"133-136","source":"Crossref","is-referenced-by-count":8,"title":["High\u2010grade histologic lesions in women with low\u2010grade squamous intraepithelial lesion cytology from a region of Thailand with a high incidence of cervical cancer"],"prefix":"10.1002","volume":"110","author":[{"given":"Rattapon","family":"Kiatiyosnusorn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prapaporn","family":"Suprasert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jatupol","family":"Srisomboon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sitthicha","family":"Siriaree","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surapan","family":"Khunamornpong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chumnan","family":"Kietpeerakool","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,5,15]]},"reference":[{"key":"e_1_2_6_2_2","series-title":"Cancer in Thailand","first-page":"51","volume-title":"Cervix uteri","author":"Srivatanakul P.","year":"2007"},{"issue":"10","key":"e_1_2_6_3_2","first-page":"1992","article-title":"The 2001 Bethesda System terminology","volume":"68","author":"Apgar B.S.","year":"2003","journal-title":"Am Fam Physician"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2006.00405.x"},{"issue":"4","key":"e_1_2_6_5_2","first-page":"212","article-title":"Correlating Papanicolaou Smear, Colposcopic Impression, and Biopsy: Results from the Women's Interagency HIV Study","volume":"5","author":"Massad L.S.","year":"2001","journal-title":"J Low Genit Tract Dis"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2003.282"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.2001.6323"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(03)00413-7"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2004.00223.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20462"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6601415"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61684-5"},{"issue":"4","key":"e_1_2_6_13_2","first-page":"785","article-title":"Clinical relevance of atypical squamous cells of undetermined significance by the 2001 bethesda system: experience from a cervical cancer high incidence region","volume":"9","author":"Kantathavorn N.","year":"2008","journal-title":"Asian Pac J Cancer Prev"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2006.00411.x"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1086\/323081"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00126334-199905010-00005"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-06-0556"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.07.047"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23121"},{"key":"e_1_2_6_20_2","volume-title":"Colposcopy and Programme Management. 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