{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T15:13:05Z","timestamp":1792249985852,"version":"4.4.0"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,1,22]],"date-time":"2011-01-22T00:00:00Z","timestamp":1295654400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2011,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To provide an updated estimation of the accuracy of visual inspection with acetic acid (VIA) in detecting true disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A PubMed search provided original studies on VIA accuracy in which the gold standard for confirmatory testing was histology alone or colposcopy followed by biopsy. The numbers of true\u2010positive, false\u2010positive, false\u2010negative, and true\u2010negative results were extracted from each study. Meta\u2010analyses were then performed with different categories of studies according to confirmatory diagnosis threshold, category of women who received confirmatory testing, and whether a medical condition that could affect VIA accuracy was present at screening. The reference category consisted of 26 studies in which VIA was performed on asymptomatic women who all underwent confirmatory testing and in which the disease threshold was cervical intraepithelial neoplasia grade 2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We report an 80% sensitivity (range, 79%\u201382%) and a 92% specificity (range, 91%\u201392%) for VIA. Study region, capacity of screener, or size of the study population did not modify VIA accuracy. The positive predictive value was 10% (range, 9%\u201310%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Screening for precancerous and cancerous cervical lesions using VIA is a simple, low\u2010cost, and efficient alternative to cytologic testing in low\u2010resource areas.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2010.10.012","type":"journal-article","created":{"date-parts":[[2011,1,23]],"date-time":"2011-01-23T09:18:58Z","timestamp":1295774338000},"page":"14-24","source":"Crossref","is-referenced-by-count":193,"title":["Accuracy of visual inspection with acetic acid for cervical cancer screening"],"prefix":"10.1002","volume":"113","author":[{"given":"Catherine","family":"Sauvaget","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Marie","family":"Fayette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Muwonge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramani","family":"Wesley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rengaswamy","family":"Sankaranarayanan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,1,22]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2005.01.009"},{"key":"e_1_2_6_3_2","first-page":"210","article-title":"Early diagnosis of carcinoma of the cervix","volume":"56","author":"Schiller W.","year":"1933","journal-title":"Surg Gynaecol Obstet"},{"key":"e_1_2_6_4_2","unstructured":"IARC Working Group on Evaluation of Cancer Preventive Strategies.Cervix cancer screeningwww.iarc.frhttp:\/\/www.iarc.fr\/en\/publications\/pdfs\u2010online\/prev\/handbook10\/index.php Published 2005"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/154.4.389"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.OGX.0000079632.98372.26"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/030089169307900104"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20000815)89:4<826::AID-CNCR15>3.0.CO;2-5"},{"issue":"2","key":"e_1_2_6_9_2","first-page":"88","article-title":"Detection of CIN by naked eye visualization after application of acetic acid","volume":"34","author":"Londhe M.","year":"1997","journal-title":"Indian J Cancer"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(96)00189-5"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19981115)83:10<2150::AID-CNCR13>3.0.CO;2-0"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19990105)80:1<161::AID-IJC28>3.0.CO;2-8"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)07033-0"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23489"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-005-0296-4"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(03)00177-X"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.2188\/jea.16.145"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0808516"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-120-8-199404150-00008"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.lgt.0000210126.08640.4e"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-36342005000100007"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1159\/000325616"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.21972"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1177\/1740774508096139"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-132-10-200005160-00009"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.298.6675.707"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a117485"},{"issue":"4","key":"e_1_2_6_28_2","first-page":"626","article-title":"Colposcopy for the diagnosis of squamous intraepithelial lesions: a meta\u2010analysis","volume":"91","author":"Mitchell M.F.","year":"1998","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(08)70210-9"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.22991"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2009.02122.x"}],"container-title":["International Journal of Gynecology &amp; 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