{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:07:04Z","timestamp":1790086024639,"version":"4.0.1"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,3,31]],"date-time":"2011-03-31T00:00:00Z","timestamp":1301529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2011,3,31]],"date-time":"2011-03-31T00:00:00Z","timestamp":1301529600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","award":["2004\u201305330"],"award-info":[{"award-number":["2004\u201305330"]}],"id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare modalities for diagnosing genital tuberculosis (GTB) and to assess fertility outcome after antitubercular therapy (ATT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Infertile women underwent endometrial aspiration (EA) and peritoneal washing (PW) for histopathologic examination, PCR, and acid\u2010fast bacilli (AFB) smear and culture of\n                      <jats:italic>Mycobacterium tuberculosis<\/jats:italic>\n                      ; laparoscopy and hysteroscopy were also performed. Women with a positive laboratory test and\/or laparoscopic finding classified as definitive\/probable received ATT for 6 months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 196 women recruited, 187 underwent laparoscopy. Genital tuberculosis was diagnosed in 118 (60.2%). In 41.3%, EA PCR was positive; PW PCR was positive in 7.6%. The remaining laboratory tests were positive in a small number. Laparoscopy indicated definitive GTB in 9.1% and probable GTB in 37.4%. Among the 118 women treated for GTB, 22.9% conceived without in vitro fertilization; of these women, 74.1% had a positive EA PCR and 59.3% had a positive laparoscopy finding. A quarter of the women received ATT solely on the basis of the PCR result and 31.0% of these women conceived.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>No single test can detect all instances of GTB. A combination of tests is needed to increase the detection rate. Treatment given solely on the basis of a positive PCR result can result in conception.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijgo.2010.12.014","type":"journal-article","created":{"date-parts":[[2011,4,15]],"date-time":"2011-04-15T06:52:50Z","timestamp":1302850370000},"page":"229-234","source":"Crossref","is-referenced-by-count":44,"title":["Genital tuberculosis among infertile women and fertility outcome after antitubercular therapy"],"prefix":"10.1002","volume":"113","author":[{"given":"Vidushi","family":"Kulshrestha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alka","family":"Kriplani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nutan","family":"Agarwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urvashi B.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanu","family":"Rana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,3,31]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"600","article-title":"Pelvic tuberculosis","volume":"14","author":"Malkani P.K.","year":"1959","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00207681"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-008-0590-y"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7292(92)90492-2"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(01)00525-2"},{"issue":"4","key":"e_1_2_6_7_2","first-page":"418","article-title":"Newer diagnostic techniques for tuberculosis","volume":"120","author":"Katoch V.M.","year":"2004","journal-title":"Indian J Med Res"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.76.6.757"},{"issue":"10","key":"e_1_2_6_9_2","first-page":"929","article-title":"Diagnosis of culture\u2010negative female genital tract tuberculosis with peritoneal involvement by polymerase chain reaction","volume":"46","author":"Baum S.E.","year":"2001","journal-title":"J Reprod Med"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199001183220307"},{"issue":"7","key":"e_1_2_6_11_2","first-page":"468","article-title":"Endoscopy in the diagnosis of genital tuberculosis","volume":"34","author":"Merchant R.","year":"1989","journal-title":"J Reprod Med"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2006.12.018"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-197603000-00016"},{"issue":"9","key":"e_1_2_6_14_2","first-page":"1045","article-title":"An algorithmic approach to female genital tuberculosis causing infertility","volume":"10","author":"Jindal U.N.","year":"2006","journal-title":"Int J Tuberc Lung Dis"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.45943-0"},{"key":"e_1_2_6_16_2","first-page":"260","article-title":"Use of polymerase chain reaction for diagnosis of endometrial tuberculosis in high risk subfertile women in an endemic zone","volume":"53","author":"Roy H.","year":"2003","journal-title":"J Obstet Gynecol India"},{"key":"e_1_2_6_17_2","first-page":"423","article-title":"Evaluation of women with infertility and genital tuberculosis","volume":"56","author":"Rozati R.","year":"2006","journal-title":"J Obstet Gynecol India"},{"key":"e_1_2_6_18_2","first-page":"395","volume-title":"Tuberculosis and obstetric and gynaecological practice","author":"Sharma J.B.","year":"2008"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.025080-0"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1159\/000091498"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(97)80076-3"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)58101-1"},{"issue":"12","key":"e_1_2_6_23_2","first-page":"630","article-title":"Genital tuberculosis associated with female infertility in the western Cape","volume":"77","author":"De Vynck W.E.","year":"1990","journal-title":"S Afr Med J"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1022533016670"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01201795"},{"issue":"173","key":"e_1_2_6_26_2","first-page":"52","article-title":"A ten year clinicopathological study of female genital tuberculosis and impact on fertility","volume":"48","author":"Mondal S.K.","year":"2009","journal-title":"JNMA J Nepal Med Assoc"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(75)90363-4"}],"container-title":["International Journal of Gynecology &amp; 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