{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T23:47:58Z","timestamp":1790898478004,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,2,23]],"date-time":"2011-02-23T00:00:00Z","timestamp":1298419200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate pre\u2010eclampsia\/eclampsia\u2010associated maternal mortality in high\u2010income countries to understand better the potential improvements in pre\u2010eclampsia\/eclampsia\u2010related mortality in low\u2010income countries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We searched Medline, PubMed, and the Cochrane Database (1900\u20132010) using relevant search terms. Studies of the incidence of pre\u2010eclampsia\/eclampsia and case fatality rates in various geographic regions were included. The incidence of pre\u2010eclampsia\/eclampsia and the pre\u2010eclampsia\/eclampsia\u2010associated case fatality rates are presented by location and year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Most declines in maternal mortality associated with pre\u2010eclampsia\/eclampsia in high\u2010income countries occurred between 1940 and 1970 and were associated with a 90% reduction in the incidence of eclampsia and a 90% reduction in the case fatality rate in women with eclampsia. The most important interventions were widespread use of prenatal care with blood pressure and urine protein measurement, and increased access to hospital care for timely induction of labor or cesarean delivery for women with severe pre\u2010eclampsia or seizures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A substantial reduction in pre\u2010eclampsia\/eclampsia\u2010related mortality could be made in low\u2010income countries by widespread hypertension and proteinuria screening and early delivery of women with severe disease. Magnesium sulfate may reduce mortality, but should not be the cornerstone of maternal mortality reduction programs.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2011.01.002","type":"journal-article","created":{"date-parts":[[2011,2,24]],"date-time":"2011-02-24T13:43:46Z","timestamp":1298555026000},"page":"91-95","source":"Crossref","is-referenced-by-count":91,"title":["Lessons for low\u2010income regions following the reduction in hypertension\u2010related maternal mortality in high\u2010income countries"],"prefix":"10.1002","volume":"113","author":[{"given":"Robert L.","family":"Goldenberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth M.","family":"McClure","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily R.","family":"MacGuire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beena D.","family":"Kamath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan H.","family":"Jobe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,2,23]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/72.1.241S"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-198412000-00004"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(00)01223-0"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61572-4"},{"key":"e_1_2_6_6_2","unstructured":"World Health Organization.Maternal mortality in 2005: Estimates developed by WHO UNICEF UNFPA and The World Bankwww.who.inthttp:\/\/whqlibdoc.who.int\/publications\/2007\/9789241596213_eng.pdf Published 2007"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60518-1"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68397-9"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1992.tb13818.x"},{"key":"e_1_2_6_10_2","unstructured":"World Bank Group.How we Classify Countrieswww.worldbank.orghttp:\/\/data.worldbank.org\/about\/country\u2010classifications Accessed 2010. 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