{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T16:01:48Z","timestamp":1782316908707,"version":"3.54.5"},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,1,18]],"date-time":"2012-01-18T00:00:00Z","timestamp":1326844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine whether magnesium sulfate (MgSO<jats:sub>4<\/jats:sub>) prophylaxis is needed for up to 24 hours postpartum in all patients with pre\u2010eclampsia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a randomized open clinical trial conducted in a tertiary health center in India between September 2008 and April 2010, 150 women with severe pre\u2010eclampsia who received intrapartum MgSO<jats:sub>4<\/jats:sub> and delivered at more than 20 weeks gestation were enrolled. After 6 hours postpartum, the participants were randomized to continue receiving (control group) or to discontinue (intervention group) MgSO<jats:sub>4<\/jats:sub>, and outcomes were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Administration of MgSO<jats:sub>4<\/jats:sub> had to be reinstituted for 1 woman in the intervention group. Under the current protocol in the institution, all 75 women in the intervention group would have received MgSO<jats:sub>4<\/jats:sub> for 24 hours postpartum. A significant reduction in time spent by the doctors (<jats:italic>P<\/jats:italic> &lt; 0.001) and nurses (<jats:italic>P<\/jats:italic> &lt; 0.001) was seen in the intervention group. The pain score in the intervention group was significantly less (<jats:italic>P<\/jats:italic> &lt; 0.001), and women in the intervention group were able to look after themselves better (<jats:italic>P<\/jats:italic> &lt; 0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>For women at low risk for postpartum eclampsia, a shortened (6\u2010hour) MgSO<jats:sub>4<\/jats:sub> regime was as effective for seizure prophylaxis as the conventional 24\u2010hour regime, with significant benefits in terms of cost and morbidity.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2011.09.028","type":"journal-article","created":{"date-parts":[[2012,1,18]],"date-time":"2012-01-18T05:15:45Z","timestamp":1326863745000},"page":"237-239","source":"Crossref","is-referenced-by-count":19,"title":["A shortened postpartum magnesium sulfate prophylaxis regime in pre\u2010eclamptic women at low risk of eclampsia"],"prefix":"10.1002","volume":"116","author":[{"given":"Lalthakimi","family":"Darngawn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rubi","family":"Jose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anni","family":"Regi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramandeep","family":"Bansal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laxmanan","family":"Jeyaseelan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,1,18]]},"reference":[{"issue":"12","key":"e_1_2_6_2_2","first-page":"2317","article-title":"Diagnosis and management of preeclampsia","volume":"70","author":"Wagner L.K.","year":"2004","journal-title":"Am Fam Physician"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)91034-4"},{"issue":"3","key":"e_1_2_6_4_2","first-page":"328","article-title":"Postpartum eclampsia: a recurring perinatal dilemma","volume":"76","author":"Miles J.F.","year":"1990","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08778-0"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.grf.0000160314.59736.d2"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(98)70195-4"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200301000-00015"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000236493.35347.d8"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2001.801105.x"},{"issue":"5","key":"e_1_2_6_11_2","first-page":"402","article-title":"In search of accelerated recovery from eclampsia","volume":"56","author":"Bhargava A.","year":"2006","journal-title":"J Obstet Gynecol India"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0020729211005650?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0020729211005650?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2Fj.ijgo.2011.09.028","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2Fj.ijgo.2011.09.028","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.ijgo.2011.09.028","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T13:27:32Z","timestamp":1696512452000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1016\/j.ijgo.2011.09.028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,18]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["10.1016\/j.ijgo.2011.09.028"],"URL":"https:\/\/doi.org\/10.1016\/j.ijgo.2011.09.028","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,18]]}}}