{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T21:36:15Z","timestamp":1758404175979},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,1,20]],"date-time":"2012-01-20T00:00:00Z","timestamp":1327017600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the role of genital pathogens in postoperative morbidity following diathermy loop excision of the transformation zone (LETZ) of the uterine cervix.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with cervical intraepithelial neoplasia (CIN) who underwent diathermy LETZ were included in a prospective study. Cervical swabs for genital pathogens were collected before the diathermy procedure. After surgery, women were followed\u2010up regarding the occurrence and severity of postoperative pain, bleeding, and discharge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Genital pathogens were present in 463 of 788 (58.8%) cases. The most frequently isolated groups of microorganisms were group B \u03b2\u2010hemolytic <jats:italic>Streptococcus<\/jats:italic>, \u03b1\u2010hemolytic <jats:italic>Streptococcus<\/jats:italic>, <jats:italic>Enterococcus<\/jats:italic> species, and coliforms. In patients with genital pathogens, postoperative pain was present in 298 (37.8%), discharge in 262 (33.2%), and bleeding in 236 (29.9%) cases. In patients without genital pathogens, 199 (25.3%) experienced pain, 181 (23.0%) discharge, and 143 (18.1%) bleeding. The differences between the 2 groups were not statistically significant (<jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup> for pain = 0.675; <jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup> for discharge = 0.031; <jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup> for bleeding = 3.444; <jats:italic>P<\/jats:italic> &gt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Genital pathogens are very common among patients with CIN and do not affect the occurrence or severity of pain, discharge, or postoperative bleeding after diathermy LETZ.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2011.11.015","type":"journal-article","created":{"date-parts":[[2012,1,25]],"date-time":"2012-01-25T15:51:12Z","timestamp":1327506672000},"page":"27-29","source":"Crossref","is-referenced-by-count":3,"title":["The role of genital pathogens in morbidity following diathermy loop excision of the transformation zone of the uterine cervix"],"prefix":"10.1002","volume":"117","author":[{"given":"Darja","family":"Arko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andra\u017e","family":"Dovnik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Fokter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iztok","family":"Taka\u010d","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,1,20]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)70016-9"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1989.tb03380.x"},{"key":"e_1_2_6_4_2","first-page":"191","volume-title":"European Guidelines for Quality Assurance in Cervical Cancer Screening","author":"Jordan J.","year":"2008"},{"issue":"6","key":"e_1_2_6_5_2","first-page":"CD001318","article-title":"Surgery for cervical intraepithelial neoplasia","author":"Martin\u2010Hirsch P.P.","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1992.tb14401.x"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2009.02263.x"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2009.20.1.39"},{"issue":"4","key":"e_1_2_6_9_2","first-page":"310","article-title":"Correlation between squamous intraepithelial lesions (SILs) and bacterial vaginosis","volume":"28","author":"Vetrano G.","year":"2007","journal-title":"Eur J Gynaecol Oncol"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20431"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-0997(1999)7:3<169::AID-IDOG10>3.0.CO;2-J"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016349609065742"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/01443619750114239"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2007.01417.x"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1080\/01443619964328"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1998.tb10268.x"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.306.6886.1173"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1002611107"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpag.2008.01.073"},{"issue":"2","key":"e_1_2_6_20_2","first-page":"76","article-title":"Complications of outpatient LLETZ procedures","volume":"49","author":"Dunn T.S.","year":"2004","journal-title":"J Reprod Med"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1994.1308"},{"issue":"2","key":"e_1_2_6_22_2","first-page":"173","article-title":"Treatment of cervical intraepithelial neoplasia using the loop electrosurgical excision procedure","volume":"79","author":"Wright T.C.","year":"1992","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1995.1144"},{"issue":"2","key":"e_1_2_6_24_2","first-page":"533","article-title":"Loop excision of the transformation zone (LETZ) as an outpatient method of management for women with cervical intraepithelial neoplasia: our experience","volume":"22","author":"Ljubojevi\u0107 N.","year":"1998","journal-title":"Coll Antropol"},{"issue":"3","key":"e_1_2_6_25_2","first-page":"11","article-title":"A prospective study of the correlation between Chlamydia trachomatis infection and secondary bleeding following large loop excision of the transformation zone (LLETZ)","volume":"113","author":"Arko D.","year":"2001","journal-title":"Wien Klin Wochenschr"}],"container-title":["International Journal of Gynecology &amp; 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