{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T12:15:23Z","timestamp":1764332123117,"version":"3.37.3"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,3,21]],"date-time":"2013-03-21T00:00:00Z","timestamp":1363824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":894,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HD 55 3466","HD 44 004","HD 38 753"],"award-info":[{"award-number":["HD 55 3466","HD 44 004","HD 38 753"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["810\u20132054"],"award-info":[{"award-number":["810\u20132054"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HD 55 3466","HD 44 004","HD 38 753"],"award-info":[{"award-number":["HD 55 3466","HD 44 004","HD 38 753"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["810-2054"],"award-info":[{"award-number":["810-2054"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ijgo.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To estimate the association between unmonitored use of injections during labor and intrapartum\u2010related neonatal mortality and morbidity among home births.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Recently delivered women in Sarlahi, Nepal, reported whether they had received injections during labor. Data on breathing and crying status at birth, time to first breath, respiratory rate, sucking ability, and lethargy were gathered. Neonatal respiratory depression (NRD) and encephalopathy (NE) were compared by injection receipt status using multivariate regression models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Injections during labor were frequently reported (7108 of 22 352 [31.8%]) and were predominantly given by unqualified village \u201cdoctors.\u201d Multivariate analysis (excluding facility births and complicated deliveries) revealed associations with intrapartum\u2010related NRD (relative risk [RR] 2.52; 95% CI, 2.29\u20132.78) and NE (RR 3.48; 95% CI, 2.46\u20134.93). The risks of neonatal death associated with intrapartum\u2010related NRD (RR 3.78; 95% CI, 2.53\u20135.66) or NE (RR 4.47; 95% CI, 2.78\u20137.19) were also elevated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Injection during labor was widespread at the community level. This practice was associated with poor outcomes and possibly related to the inappropriate use of uterotonics by unqualified providers. Interventions are required to increase the safety of childbirth in the community and in peripheral health facilities.<\/jats:p><jats:p>Parent trial registered at <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">clinicaltrials.gov<\/jats:ext-link> (NCT00 109616).<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2013.02.013","type":"journal-article","created":{"date-parts":[[2013,3,21]],"date-time":"2013-03-21T18:31:34Z","timestamp":1363890694000},"page":"22-26","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Injections during labor and intrapartum\u2010related hypoxic injury and mortality in rural southern Nepal"],"prefix":"10.1002","volume":"122","author":[{"given":"Luke C.","family":"Mullany","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subarna K.","family":"Khatry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne","family":"Katz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia K.","family":"Stanton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne C.C.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary L.","family":"Darmstadt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven C.","family":"LeClerq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James M.","family":"Tielsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,3,21]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2009.07.016"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60560-1"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-8080(07)30320-0"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2008.174"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2393-10-50"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1525\/maq.2003.17.1.49"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2005.05.008"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2008.08.009"},{"issue":"1","key":"e_1_2_6_10_2","doi-asserted-by":"crossref","first-page":"35.e1","DOI":"10.1016\/j.ajog.2008.06.010","article-title":"Oxytocin: new perspectives on an old drug","volume":"200","author":"Clark S.L.","year":"2009","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2009.12.001"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1991.tb11851.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.320.7244.1229"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7292(95)02389-T"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2011.05.003"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.2012.647405"},{"key":"e_1_2_6_17_2","unstructured":"World Health Organization.Clarifying WHO position on misoprostol use in the community to reduce maternal death.http:\/\/whqlibdoc.who.int\/hq\/2010\/WHO_RHR_10.11_eng.pdf Published 2010"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1891\/215652811795481177"},{"issue":"1","key":"e_1_2_6_19_2","first-page":"76","article-title":"Joint statement: management of the third stage of labour to prevent post\u2010partum haemorrhage","volume":"49","author":"International Confederation of Midwives","year":"2004","journal-title":"J Midwifery Womens Health"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-1192"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68381-5"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-3590"},{"issue":"1","key":"e_1_2_6_23_2","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1542\/peds.98.1.141","article-title":"Use and abuse of the Apgar score","volume":"98","author":"Committee on Fetus and Newborn","year":"1996","journal-title":"Pediatrics"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4755-7-16"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-981433"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2010.12.015"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0020729213001306?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0020729213001306?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2Fj.ijgo.2013.02.013","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2Fj.ijgo.2013.02.013","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.ijgo.2013.02.013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T02:20:56Z","timestamp":1696558856000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1016\/j.ijgo.2013.02.013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,21]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["10.1016\/j.ijgo.2013.02.013"],"URL":"https:\/\/doi.org\/10.1016\/j.ijgo.2013.02.013","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"type":"print","value":"0020-7292"},{"type":"electronic","value":"1879-3479"}],"subject":[],"published":{"date-parts":[[2013,3,21]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Injections during labor and intrapartum-related hypoxic injury and mortality in rural southern Nepal","name":"articletitle","label":"Article Title"},{"value":"International Journal of Gynecology & Obstetrics","name":"journaltitle","label":"Journal Title"},{"value":"http:\/\/dx.doi.org\/10.1016\/j.ijgo.2013.02.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}