{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T16:55:12Z","timestamp":1773680112831,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,9,10]],"date-time":"2013-09-10T00:00:00Z","timestamp":1378771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":721,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["ijgo.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the prevalence of invasive cervical cancer (ICC) and assess access to, and outcomes of, treatment for ICC among HIV\u2010infected women in Kisumu, Kenya.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective chart review to identify women diagnosed with ICC between October 2007 and June 2012, and to examine the impact of a change in the referral protocol. Prior to June 2009, all women with ICC were referred to a regional hospital. After this date, women with stage IA1 disease were offered treatment with loop electrosurgical excision procedure (LEEP) in\u2010clinic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 4308 women screened, 58 (1.3%) were diagnosed with ICC. The mean age at diagnosis was 34 years (range, 22\u201350 years). Fifty\u2010four (93.1%) women had stage IA1 disease, of whom 36 (66.7%) underwent LEEP, 7 (12.9%) had a total abdominal hysterectomy, and 11 (20.4%) had unknown or no treatment. At 6, 12, and 24 months after LEEP, 8.0% (2\/25), 25.0% (6\/24), and 41.2% (7\/17) of women had a recurrence of cervical intraepithelial neoplasia 2 or worse, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Most HIV\u2010positive women diagnosed with ICC through screening had early\u2010stage disease. The introduction of LEEP in\u2010clinic increased access to treatment; however, recurrence was high, indicating the need for continued surveillance.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2013.07.010","type":"journal-article","created":{"date-parts":[[2013,9,10]],"date-time":"2013-09-10T15:37:30Z","timestamp":1378827450000},"page":"231-235","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Prevalence, characteristics, and outcomes of HIV\u2010positive women diagnosed with invasive cancer of the cervix in Kenya"],"prefix":"10.1002","volume":"123","author":[{"given":"Chemtai","family":"Mungo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig R.","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"May","family":"Maloba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth A.","family":"Bukusi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan J.","family":"Huchko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,10]]},"reference":[{"issue":"2","key":"e_1_2_6_2_2","first-page":"127","article-title":"Situation analysis for cervical cancer diagnosis and treatment in east, central and southern African countries","volume":"79","author":"Chirenje Z.M.","year":"2001","journal-title":"Bull World Health Organ"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.17.2173"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2008.04.031"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6874-10-11"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0b013e3283495a3f"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61195-7"},{"key":"e_1_2_6_8_2","article-title":"Cervical Cancer Screening and Treatment in HIV\u2010infected Women in Kisumu, Kenya: An Assessment of the Feasibility, Validity and Safety of New Techniques","volume":"1","author":"Huchko M.","year":"2010","journal-title":"KEMRI CCSP Safety and Validation Trial"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-8080(08)32415-X"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2006.01.018"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/00016340802596009"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.11.010"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31822b0991"},{"key":"e_1_2_6_14_2","unstructured":"WooV.G. CohenC.R. BukusiE.A. HuchkoM.J.Decreasing CD4 + Count is Associated with Increased Rate of Recurrent Cervical Disease in HIV\u2010positive Kenyan Women after Surgical Treatment Paper presented at: CROI; February 27\u2013March 2 2011; Boston MA.2011"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/953743"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2003.07.005"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(01)00560-4"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1438.2001.01022.x"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1080\/01443610500294599"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2004.10.002"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200309050-00015"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.2217\/WHE.10.73"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2010.10.027"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0020729213004402?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S0020729213004402?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2Fj.ijgo.2013.07.010","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2Fj.ijgo.2013.07.010","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.ijgo.2013.07.010","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T12:42:29Z","timestamp":1732884149000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1016\/j.ijgo.2013.07.010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,10]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["10.1016\/j.ijgo.2013.07.010"],"URL":"https:\/\/doi.org\/10.1016\/j.ijgo.2013.07.010","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prevalence, characteristics, and outcomes of HIV-positive women diagnosed with invasive cancer of the cervix in Kenya","name":"articletitle","label":"Article Title"},{"value":"International Journal of Gynecology & Obstetrics","name":"journaltitle","label":"Journal Title"},{"value":"http:\/\/dx.doi.org\/10.1016\/j.ijgo.2013.07.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}