{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T09:58:08Z","timestamp":1776851888551,"version":"3.51.2"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,11,22]],"date-time":"2013-11-22T00:00:00Z","timestamp":1385078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":648,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["ijgo.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To carry out long\u2010term analysis of the presence of endothelial dysfunction after the development of pregnancy\u2010induced hypertension (PIH).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a retrospective cohort study, data were analyzed from 60 women who delivered at a tertiary maternity hospital in Fortaleza, Ceara, Brazil, between 1992 and 2002. Thirty women had a history of PIH and 30 had no history of complications. Anthropometric and laboratory data were collected, and endothelial function was evaluated by flow\u2010mediated dilatation of the brachial artery. Continuous variables were analyzed via Student <jats:italic>t<\/jats:italic> test, and Mann\u2013Whitney test was used to compare means. Clinical and metabolic measures were categorized according to cardiovascular risk by cutoff points determined by national consensus; \u03c7<jats:sup>2<\/jats:sup> and Fisher exact tests were used to compare the groups. Relative risk was calculated for variables that were statistically significant (<jats:italic>P<\/jats:italic> &lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Women with a history of PIH had higher body mass index (<jats:italic>P<\/jats:italic> = 0.03), systolic blood pressure (<jats:italic>P<\/jats:italic> = 0.03), low\u2010density lipoprotein cholesterol (<jats:italic>P<\/jats:italic> = 0.02), and fasting glucose (<jats:italic>P<\/jats:italic> = 0.02) compared with women with no pregnancy complications. The frequency of endothelial dysfunction was 60% among all women, with a significant difference between the 2 groups (<jats:italic>P<\/jats:italic> = 0.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Women with a history of PIH were found to have a higher frequency of long\u2010term endothelial dysfunction.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2013.08.016","type":"journal-article","created":{"date-parts":[[2013,11,22]],"date-time":"2013-11-22T08:45:34Z","timestamp":1385109934000},"page":"230-234","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"title":["Endothelial dysfunction after pregnancy\u2010induced hypertension"],"prefix":"10.1002","volume":"124","author":[{"given":"Ana C.P.T.","family":"Henriques","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco H.C.","family":"Carvalho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helv\u00e9cio N.","family":"Feitosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raimunda H.M.","family":"Macena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa M.S.","family":"Mota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00falio C.G.","family":"Alencar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,11,22]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.4103\/1596-3519.56233"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1519-38292010000200008"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.102.014977"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67726-4"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(00)70521-7"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000135975.90889.60"},{"issue":"2","key":"e_1_2_6_8_2","first-page":"231","article-title":"Clinical relevance of angiogenese factor in preeclampsia","volume":"36","author":"Teixeira P.G.","year":"2008","journal-title":"Femina"},{"issue":"4","key":"e_1_2_6_9_2","doi-asserted-by":"crossref","first-page":"H1389","DOI":"10.1152\/ajpheart.00298.2003","article-title":"Impairment of endothelial function in women with a history of preeclampsia: an indicator of cardiovascular risk","volume":"286","author":"Agatisa P.K.","year":"2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.12.1607"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000251522.18094.d4"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjh.0000217859.27864.19"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000051384.43104.FC"},{"key":"e_1_2_6_14_2","unstructured":"Brazilian Association for the Study of Obesity and Metabolic Syndrome.Brazilian Guidelines on Obesity 2009\/2010.http:\/\/www.abeso.org.br\/pdf\/diretrizes_brasileiras_obesidade_2009_2010_1.pdf Published 2009. 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