{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:29:51Z","timestamp":1761676191596,"version":"3.37.3"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T00:00:00Z","timestamp":1401840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T00:00:00Z","timestamp":1401840000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":454,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["ijgo.org","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the experience of women receiving mifepristone\u2013misoprostol for early induced abortion in public sector facilities in the Federal District of Mexico City.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An open\u2010label prospective study was conducted with 1000 pregnant women who sought induced abortion with a pregnancy of up to 63 days of gestation, as measured from the date of their last menstrual period. The study was conducted in three public sector healthcare facilities: two secondary level hospitals and one primary care clinic. Women ingested 200 mg mifepristone on day 1, followed by 800 \u03bcg buccal misoprostol 24 hours later, and they returned for follow\u2010up on day 8. The primary outcome was complete abortion without recourse to surgical intervention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 971 women received mifepristone\u2013misoprostol and were included in the analysis for efficacy of treatment. The overall efficacy of the combined medical abortion regimen studied was 97.3% (n = 945); the success rate did not vary significantly by gestational age (95.9%\u2013100%; <jats:italic>P<\/jats:italic> = 0.449). Most women (n = 922, 95.0%) had a successful induced abortion with only one dose of misoprostol.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The combined mifepristone and buccal misoprostol regimen was found to be highly effective and acceptable among Mexican women. <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.ClinicalTrials.gov\">www.ClinicalTrials.gov<\/jats:ext-link>: NCT00386282.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2014.04.012","type":"journal-article","created":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T01:47:33Z","timestamp":1401846453000},"page":"82-85","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Efficacy and acceptability of a mifepristone\u2013misoprostol combined regimen for early induced abortion among women in Mexico City"],"prefix":"10.1002","volume":"127","author":[{"given":"Melanie","family":"Pe\u00f1a","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilana G.","family":"Dzuba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricio Sanhueza","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis Jorge Arellano","family":"Mendoza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Bousi\u00e9guez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Laura Garc\u00eda","family":"Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ranulfo R\u00edos","family":"Polanco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Eduardo Flores","family":"Villal\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beverly","family":"Winikoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,6,4]]},"reference":[{"key":"e_1_2_6_2_2","unstructured":"Health Information Management General Management of Planning and Coordination Sector Mexico City Ministry of Health. Extract of Patient Registration of the Legal Termination of Pregnancy Program. Published 2013."},{"key":"e_1_2_6_3_2","first-page":"CD002855","article-title":"Medical methods for first trimester abortion","volume":"11","author":"Kulier R.","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2010.09.002"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2012.03.039"},{"key":"e_1_2_6_6_2","unstructured":"World Health Organization.Safe Abortion: Technical and Policy Guidance for Health Systems. Second Edition.http:\/\/apps.who.int\/iris\/bitstream\/10665\/70914\/1\/9789241548434_eng.pdf. Published 2012. Accessed October 23 2013."},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31818d8eb4"},{"issue":"3","key":"e_1_2_6_8_2","doi-asserted-by":"crossref","DOI":"10.1016\/j.contraception.2011.12.012","article-title":"A randomized controlled trial of different buccal misoprostol doses in mifepristone medical abortion","volume":"86","author":"Chong E.","year":"2012","journal-title":"Contraception"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.5694\/mja12.10297"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/9781444313031"},{"key":"e_1_2_6_11_2","unstructured":"Royal College of Obstetricians and Gynaecologists.The Care of Women Requesting Induced Abortion: Evidence\u2010based Clinical Guideline Number 7.http:\/\/www.rcog.org.uk\/files\/rcog\u2010corp\/Abortion%20guideline_web_1.pdf Published November 2011. 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