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Histologic and cytologic samples were tested for HPV, and polymerase chain reaction (PCR) was used to genotype any HPV DNA identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 250 included women, 25 (10.0%) had ASCUS. HPV DNA was found in 15 (60.0%) women with ASCUS and 115 (51.1%) of the 225 without ASCUS. Viral typing showed that 7 (46.7%) HPV\u2010positive women with ASCUS had multiple infections with up to five different genotypes. Both low\u2010 and high\u2010risk HPV genotypes were found in ASCUS samples; the most prevalent genotypes were HPV6\/HPV11 (affecting 10 [66.7%] women), HPV51 (6 [40.0%]), and HPV16 (6 [40.0%]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>ASCUS is not an indication of HPV infection. HPV screening and genotyping would benefit women with ASCUS, because treatment can be planned according to risk of carcinogenesis.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2014.07.027","type":"journal-article","created":{"date-parts":[[2014,9,6]],"date-time":"2014-09-06T15:56:36Z","timestamp":1410018996000},"page":"23-26","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Human papillomavirus among women with atypical squamous cells of undetermined significance in southern Brazil"],"prefix":"10.1002","volume":"128","author":[{"given":"Suelen","family":"Paesi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo","family":"Correa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rcia Caldart","family":"Tregnago","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jovana","family":"Mandelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana","family":"Roesch\u2010Ely","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,6]]},"reference":[{"key":"e_1_2_6_2_2","unstructured":"Instituto Nacional de C\u00e2ncer Jos\u00e9 Alencar Gomes da Silva.2014 estimates for the gross incidence rates per 100 000 inhabitants and number of new cases of cancer according to sex and primary location (in Portuguese)http:\/\/www.inca.gov.br\/estimativa\/2014\/tabelaestados.asp?UF=BR Published 2014. 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