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Outcomes were compared between women with and without concomitant HELLP syndrome. Logistic regression analysis was performed to identify independent risk factors of maternal mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 196 eclampsia cases among 115 038 deliveries; 142 (72.4%) women had eclampsia alone and 54 (27.6%) women had concomitant HELLP syndrome. Severe systolic hypertension (\u2265 160 mm Hg), severe diastolic hypertension (\u2265 110 mm Hg), and hypertensive encephalopathy were significantly more common among women with HELLP than among those with eclampsia alone (<jats:italic>P<\/jats:italic> = 0.01 for all). There were 8 (4.1%) maternal deaths, all in the group with HELLP syndrome, and 18 (9.1%) perinatal deaths. In a multivariate regression model, maternal mortality was significantly associated with low platelet count and severe systolic hypertension (<jats:italic>P<\/jats:italic> &lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Eclampsia with HELLP syndrome is a dangerous complication associated with pregnancy. Low platelet count secondary to HELLP syndrome and severe systolic hypertension were independently associated with maternal mortality from eclampsia.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2014.11.024","type":"journal-article","created":{"date-parts":[[2015,2,7]],"date-time":"2015-02-07T19:34:34Z","timestamp":1423337674000},"page":"219-222","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Incidence of eclampsia with HELLP syndrome and associated mortality in Latin America"],"prefix":"10.1002","volume":"129","author":[{"given":"Paulino","family":"Vigil\u2010De Gracia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Rojas\u2010Suarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edwin","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osvaldo","family":"Reyes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Collantes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arelys","family":"Quintero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erasmo","family":"Huertas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9s","family":"Calle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Turcios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vicente Y.","family":"Chon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,2,7]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(00)70216-X"},{"issue":"1","key":"e_1_2_7_3_2","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1067\/mob.2000.107928","article-title":"Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy","volume":"183","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2008.09.014"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.2217\/WHE.11.57"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(90)91176-D"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2012.09.026"},{"issue":"1","key":"e_1_2_7_8_2","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.preghy.2011.01.004","article-title":"The HELLP syndrome (hemolysis, elevated liver enzymes and low platelets): Clinical characteristics and maternal\u2010fetal outcome in 172 patients","volume":"1","author":"Miranda M.L.","year":"2011","journal-title":"Pregnancy Hypertens"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(98)00003-4"},{"key":"e_1_2_7_10_2","first-page":"545","article-title":"Eclampsia in Central America","volume":"70","author":"Vigil\u2010De Gracia P.","year":"2002","journal-title":"Ginecol Obstet Mex"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/10641950701826612"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2011.11.009"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2007.01423.x"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31823311c1"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08778-0"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1266155"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.3109\/10641955.2010.525277"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2012.678432"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(98)00010-1"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.10.593"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.309.6966.1395"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2013-003225"}],"container-title":["International Journal of Gynecology &amp; 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