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After Marlise Mu\u00f1oz\u2014who was at 14 weeks of pregnancy when she developed a pulmonary embolism\u2014was pronounced brain dead, hospital officials initially refused to withdraw support, citing a Texas state law requiring them to maintain life\u2010sustaining treatment for a pregnant patient to help to save the fetus. By contrast, when Robyn Benson was pronounced brain dead after a brain hemorrhage at 22 weeks of pregnancy, both her husband and the physicians agreed to continue support until a viable child could be delivered. The Mu\u00f1oz and Benson cases offer an opportunity to explore the medical, legal, and ethical issues surrounding catastrophic brain injury in pregnant women. It is hoped that the present article will enable clinicians to better appreciate the history and present state of issues involving advance directives for pregnant women, maternal versus fetal interests, and the impact of fetal viability on medical decision making, as well as offer a practical assessment of the various US state laws concerning the rare, yet catastrophic event of brain injury in a pregnant woman.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2014.12.011","type":"journal-article","created":{"date-parts":[[2015,3,3]],"date-time":"2015-03-03T13:25:56Z","timestamp":1425389156000},"page":"276-280","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Medical, legal, and ethical challenges associated with pregnancy and catastrophic brain injury"],"prefix":"10.1002","volume":"129","author":[{"given":"Christopher M.","family":"Burkle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Tessmer\u2010Tuck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eelco F.","family":"Wijdicks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,3,3]]},"reference":[{"key":"e_1_2_10_2_2","unstructured":"Plaintiff's original petition for declaratory judgment and application for unopposed expedited relief cause No. 017\u2010270080\u201014.http:\/\/thaddeuspope.com\/images\/Munoz_v._JPS_Jan_2014_.pdf Accessed February 6 2015"},{"key":"e_1_2_10_3_2","unstructured":"ChappellB.Judge tells hospital to take pregnant woman off life support.http:\/\/www.npr.org\/blogs\/thetwo\u2010way\/2014\/01\/24\/265785603\/judge\u2010tells\u2010hospital\u2010to\u2010take\u2010pregnant\u2010woman\u2010off\u2010life\u2010support Published January 24 2014. 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