{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T16:00:56Z","timestamp":1782316856671,"version":"3.54.5"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,10,14]],"date-time":"2015-10-14T00:00:00Z","timestamp":1444780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2015,10,14]],"date-time":"2015-10-14T00:00:00Z","timestamp":1444780800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["ijgo.org","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the effectiveness of a reduced duration (12 hours) of magnesium sulfate (MgSO<jats:sub>4<\/jats:sub>) administration for eclampsia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a prospective randomized study, women with eclampsia (prepartum, intrapartum, or postpartum) attending Jawaharlal Nehru Medical College, Aligarh, India, between January 2012 and September 2013 were enrolled. The inclusion criteria were blood pressure of at least 140\/90 mm Hg after 20 weeks, proteinuria (dipstick value \u2265 + 1), and seizures not attributed to other causes. Participants were assigned to control and study groups according to the time of enrollment (6\u2010month blocks). All patients received a MgSO<jats:sub>4<\/jats:sub> loading dose (4 g, intravenously), followed by maintenance doses (1 g\/hour) for 12 hours (study group) and 24 hours (control group). The primary outcome was recurrent convulsions after completion of MgSO<jats:sub>4<\/jats:sub> therapy. Patients with treatment failure were excluded from analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Analyses included 132 patients in the study group and 72 patients in the control group. No convulsions recurred in either group after the completion of treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>For women with eclampsia, 12 hours of magnesium sulfate could effectively prevent recurrent convulsions.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2015.06.056","type":"journal-article","created":{"date-parts":[[2015,10,22]],"date-time":"2015-10-22T22:32:04Z","timestamp":1445553124000},"page":"68-71","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Maternal outcomes after 12 hours and 24 hours of magnesium sulfate therapy for eclampsia"],"prefix":"10.1002","volume":"132","author":[{"given":"Shaheen","family":"Anjum","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Namarata","family":"Goel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajyashri","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zehra","family":"Mohsin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nidhi","family":"Garg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,10,14]]},"reference":[{"issue":"6","key":"e_1_2_6_2_2","first-page":"39","article-title":"Prophylactic magnesium sulphate in severe preeclampsia\u2014Loading dose only vs conventional 24 hour therapy of modified Pritchard's regime\u2014A randomised trial","volume":"4","author":"Ranganna H.","year":"2014","journal-title":"IOSR J Pharm"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-2-165"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1341-8076.2002.00029.x"},{"issue":"2","key":"e_1_2_6_5_2","doi-asserted-by":"crossref","first-page":"01","DOI":"10.9790\/0853-0420105","article-title":"Eclampsia in a teaching hospital: incidence, clinical profile and response to magnesium sulphate by Zuspan's regimen","volume":"4","author":"Sunita T.H.","year":"2013","journal-title":"IOSR J Dent Med Sci"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.1994.tb01104.x"},{"issue":"2","key":"e_1_2_6_7_2","first-page":"7708","article-title":"Eclampsia in Eastern India: incidence, demographic profile and response to three different anticonvulsant regimes of magnesium sulphate","volume":"15","author":"Singh S.","year":"2010","journal-title":"Internet J Gynecol Obstet"},{"issue":"3","key":"e_1_2_6_8_2","first-page":"13","article-title":"Low dose magnesium sulphate regime for eclampsia","volume":"4","author":"Bangal V.","year":"2009","journal-title":"Pravara Med Rev"},{"issue":"6","key":"e_1_2_6_9_2","first-page":"546","article-title":"Low dose magnesium sulphate therapy for eclampsia and imminent eclampsia\u2013\u2014regime tailored for Indian women","volume":"53","author":"Sardesai S.","year":"2003","journal-title":"J Obstet Gynecol India"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)91034-4"}],"container-title":["International Journal of Gynecology &amp; 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