{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T07:37:19Z","timestamp":1792222639804,"version":"4.4.0"},"reference-count":42,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,11,28]],"date-time":"2015-11-28T00:00:00Z","timestamp":1448668800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,3]],"date-time":"2015-12-03T00:00:00Z","timestamp":1449100800000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100004423","name":"WHO","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004423","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004423","name":"World Health Organization","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004423","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ijgo.org","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Gynecology & Obstetrics"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1016\/j.ijgo.2015.07.026","type":"journal-article","created":{"date-parts":[[2015,11,28]],"date-time":"2015-11-28T17:15:50Z","timestamp":1448730950000},"page":"266-271","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":186,"title":["Systematic reviews and meta-analyses of benefits and harms of cryotherapy, LEEP, and cold knife conization to treat cervical intraepithelial neoplasia"],"prefix":"10.1002","volume":"132","author":[{"given":"Nancy","family":"Santesso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reem A.","family":"Mustafa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojtek","family":"Wiercioch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohan","family":"Kehar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shreyas","family":"Gandhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaolong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrienne","family":"Cheung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Hopkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasha","family":"Khatib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad A.","family":"Mustafa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Lloyd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Broutet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger J","family":"Sch\u00fcnemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,11,28]]},"reference":[{"issue":"(1)","key":"10.1016\/j.ijgo.2015.07.026-BIB0005|rf0005","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1097\/AOG.0b013e31818f5008","article-title":"Evidence for frequent regression of cervical intraepithelial neoplasia-grade 2","volume":"113","author":"Castle","year":"2009","journal-title":"Obstet Gynecol"},{"issue":"(5)","key":"10.1016\/j.ijgo.2015.07.026-BIB0010|rf0010","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S1470-2045(08)70103-7","article-title":"Natural history of cervical neoplasia and risk of invasive cancer in women with cervical intraepithelial neoplasia 3: a retrospective cohort study","volume":"9","author":"McCredie","year":"2008","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ijgo.2015.07.026-BIB0015|rf0015","first-page":"CD001318","article-title":"Surgery for cervical intraepithelial neoplasia","volume":"12","author":"Martin-Hirsch","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"issue":"(1)","key":"10.1016\/j.ijgo.2015.07.026-BIB0020|rf0020","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/jrsm.1078","article-title":"Non-randomized studies as a source of complementary, sequential or replacement evidence for randomized controlled trials in systematic reviews on the effects of interventions","volume":"4","author":"Sch\u00fcnemann","year":"2013","journal-title":"Res Synth Methods"},{"key":"10.1016\/j.ijgo.2015.07.026-BIB0025|rf0200","unstructured":"World Health Organization Treatment of cervical intraepithelial neoplasia 2-3 and adenocarcinoma in situ: cryotherapy, large loop excision of the transformation zone, and cold knife conization http:\/\/www.who.int\/reproductivehealth\/publications\/cancers\/treatment_CIN_2-3\/en\/"},{"key":"10.1016\/j.ijgo.2015.07.026-BIB0030|rf0220","unstructured":"Higgins J.P.T. Green S. Cochrane Handbook for Systematic Reviews of Interventions: Version 5.1.0 [updated March 2011] 2011 http:\/\/handbook.cochrane.org\/"},{"key":"10.1016\/j.ijgo.2015.07.026-BIB0035|rf0210","unstructured":"Wells G.A. Shea B. O'Connell D. Peterson J. Welch V. Losos M. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses http:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.htm"},{"issue":"(7650)","key":"10.1016\/j.ijgo.2015.07.026-BIB0040|rf0025","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"issue":"(2)","key":"10.1016\/j.ijgo.2015.07.026-BIB0045|rf0030","first-page":"70","article-title":"The hazard of cryosurgery for treatment of cervical dysplasia","volume":"19","author":"Saidi","year":"1977","journal-title":"J Reprod Med"},{"issue":"(9)","key":"10.1016\/j.ijgo.2015.07.026-BIB0050|rf0035","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1111\/j.1471-0528.2011.02944.x","article-title":"The risk of preterm birth following treatment for precancerous changes in the cervix: a systematic review and meta-analysis","volume":"118","author":"Bruinsma","year":"2011","journal-title":"BJOG"},{"issue":"(4)","key":"10.1016\/j.ijgo.2015.07.026-BIB0055|rf0040","first-page":"495","article-title":"Cryosurgical treatment of neoplasia of the uterine cervix","volume":"39","author":"Crisp","year":"1972","journal-title":"Obstet Gynecol"},{"issue":"(7)","key":"10.1016\/j.ijgo.2015.07.026-BIB0060|rf0045","doi-asserted-by":"crossref","first-page":"627","DOI":"10.3109\/00016348809004276","article-title":"Cryosurgical treatment of CIN I-III. A long-term study","volume":"67","author":"Einerth","year":"1988","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"(12)","key":"10.1016\/j.ijgo.2015.07.026-BIB0065|rf0050","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1111\/j.1471-0528.1979.tb11238.x","article-title":"A study of cryosurgery for dysplasia and carcinoma in situ of the uterine cervix","volume":"86","author":"Elmfors","year":"1979","journal-title":"Br J Obstet Gynaecol"},{"issue":"(2)","key":"10.1016\/j.ijgo.2015.07.026-BIB0070|rf0055","first-page":"245","article-title":"Fertility after cryosurgery of the cervix","volume":"52","author":"Weed","year":"1978","journal-title":"Obstet Gynecol"},{"issue":"(8888)","key":"10.1016\/j.ijgo.2015.07.026-BIB0075|rf0060","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0140-6736(94)90881-8","article-title":"Efficacy and safety of large-loop excision of the transformation zone","volume":"343","author":"Bigrigg","year":"1994","journal-title":"Lancet"},{"issue":"(3)","key":"10.1016\/j.ijgo.2015.07.026-BIB0080|rf0065","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3109\/00016347909154045","article-title":"Pregnancy complications following conization of the uterine cervix (I)","volume":"58","author":"Weber","year":"1979","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"(1)","key":"10.1016\/j.ijgo.2015.07.026-BIB0085|rf0070","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.ejogrb.2004.11.018","article-title":"Conservative treatment of cervical intraepithelial neoplasia using a cold-knife section technique","volume":"121","author":"Mazouni","year":"2005","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"(5)","key":"10.1016\/j.ijgo.2015.07.026-BIB0090|rf0075","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/S0002-9378(16)33992-8","article-title":"Cryosurgical treatment of premalignant disease of the uterine cervix","volume":"107","author":"Crisp","year":"1970","journal-title":"Am J Obstet Gynecol"},{"issue":"(5)","key":"10.1016\/j.ijgo.2015.07.026-BIB0095|rf0080","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/j.1471-0528.1982.tb05082.x","article-title":"Treatment of cervical intraepithelial neoplasia by colposcopically directed cryosurgery and subsequent pregnancy experience","volume":"89","author":"Monaghan","year":"1982","journal-title":"Br J Obstet Gynaecol"},{"issue":"(5)","key":"10.1016\/j.ijgo.2015.07.026-BIB0100|rf0085","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/0002-9378(78)90074-1","article-title":"Cryosurgery for the treatment of cervical intraepithelial neoplasia","volume":"130","author":"Popkin","year":"1978","journal-title":"Am J Obstet Gynecol"},{"issue":"(3 Pt 1)","key":"10.1016\/j.ijgo.2015.07.026-BIB0105|rf0090","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1006\/gyno.1994.1308","article-title":"Cold-knife conization versus loop excision: histopathologic and clinical results of a randomized trial","volume":"55","author":"Girardi","year":"1994","journal-title":"Gynecol Oncol"},{"issue":"(1)","key":"10.1016\/j.ijgo.2015.07.026-BIB0110|rf0095","first-page":"17","article-title":"Pregnancy outcome after treatment of cervical intraepithelial neoplasia by the loop electrosurgical excision procedure and cold knife conization","volume":"36","author":"Michelin","year":"2009","journal-title":"Clin Exp Obstet Gynecol"},{"issue":"(8)","key":"10.1016\/j.ijgo.2015.07.026-BIB0115|rf0100","first-page":"574","article-title":"Efficacy of complications of different surgical treatments in cervical intraepithelial neoplasia III [in Chinese]","volume":"44","author":"Zeng","year":"2009","journal-title":"Zhonghua Fu Chan Ke Za Zhi"},{"issue":"(1)","key":"10.1016\/j.ijgo.2015.07.026-BIB0120|rf0215","first-page":"39","article-title":"Cervical conization results and complications. A twelve-year experience","volume":"10","author":"Barrenetxea","year":"1992","journal-title":"Cervix Low Female Genit Tract"},{"issue":"(6)","key":"10.1016\/j.ijgo.2015.07.026-BIB0125|rf0110","first-page":"617","article-title":"A randomised clinical trial of loop electrosurgical excision procedure (LEEP) versus cryotherapy in the treatment of cervical intraepithelial neoplasia","volume":"21","author":"Chirenje","year":"2001","journal-title":"J Obstet Gynaecol"},{"issue":"(2)","key":"10.1016\/j.ijgo.2015.07.026-BIB0130|rf0115","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.ygyno.2006.10.011","article-title":"HPV16 and increased risk of recurrence after treatment for CIN","volume":"104","author":"G\u00f6k","year":"2007","journal-title":"Gynecol Oncol"},{"issue":"(14)","key":"10.1016\/j.ijgo.2015.07.026-BIB0135|rf0120","first-page":"522","article-title":"An evaluation of treatment modalities in cervical intra-epithelial neoplasia","volume":"63","author":"Atad","year":"1983","journal-title":"S Afr Med J"},{"issue":"(2)","key":"10.1016\/j.ijgo.2015.07.026-BIB0140|rf0125","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/0090-8258(90)90034-I","article-title":"20-year experience of follow-up of the abnormal smear with colposcopy and histology and treatment by conization or cryosurgery","volume":"38","author":"Hellberg","year":"1990","journal-title":"Gynecol Oncol"},{"issue":"(5)","key":"10.1016\/j.ijgo.2015.07.026-BIB0145|rf0130","first-page":"233","article-title":"Treatment of cervical intraepithelial neoplasia","volume":"84","author":"Lele","year":"1984","journal-title":"N Y State J Med"},{"issue":"(6)","key":"10.1016\/j.ijgo.2015.07.026-BIB0150|rf0135","first-page":"507","article-title":"Rational use of cryosurgery and cold knife conization for treatment of cervical intraepithelial neoplasia","volume":"13","author":"Loizzi","year":"1992","journal-title":"Eur J Gynaecol Oncol"},{"issue":"(10)","key":"10.1016\/j.ijgo.2015.07.026-BIB0155|rf0140","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1093\/jnci\/djp089","article-title":"Cervical intraepithelial neoplasia outcomes after treatment: long-term follow-up from the British Columbia Cohort Study","volume":"101","author":"Melnikow","year":"2009","journal-title":"J Natl Cancer Inst"},{"issue":"(2 Pt 1)","key":"10.1016\/j.ijgo.2015.07.026-BIB0160|rf0145","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/S0002-9378(99)70200-0","article-title":"Cold-knife conization versus conization by the loop electrosurgical excision procedure: a randomized, prospective study","volume":"180","author":"Duggan","year":"1999","journal-title":"Am J Obstet Gynecol"},{"issue":"(2)","key":"10.1016\/j.ijgo.2015.07.026-BIB0165|rf0150","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1006\/gyno.1994.1189","article-title":"A randomized prospective study comparing three techniques of conization: cold knife, laser, and LEEP","volume":"54","author":"Mathevet","year":"1994","journal-title":"Gynecol Oncol"},{"issue":"(3)","key":"10.1016\/j.ijgo.2015.07.026-BIB0170|rf0155","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1006\/gyno.1999.5626","article-title":"Randomized study comparing two techniques of conization: cold knife versus loop excision","volume":"75","author":"Giacalone","year":"1999","journal-title":"Gynecol Oncol"},{"issue":"(11)","key":"10.1016\/j.ijgo.2015.07.026-BIB0175|rf0160","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.ejso.2010.08.135","article-title":"Predictors of recurrence in high-grade cervical lesions and a plan of management","volume":"36","author":"Leguevaque","year":"2010","journal-title":"Eur J Surg Oncol"},{"issue":"(5)","key":"10.1016\/j.ijgo.2015.07.026-BIB0180|rf0165","first-page":"587","article-title":"Outcome after treatment of high-grade squamous intraepithelial lesions: relation between colposcopically directed biopsy, conization and cervical loop excision","volume":"25","author":"Murta","year":"2004","journal-title":"Eur J Gynaecol Oncol"},{"issue":"(4)","key":"10.1016\/j.ijgo.2015.07.026-BIB0185|rf0170","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1089\/gyn.1994.10.235","article-title":"Loop diathermy to replace conization in the conservative treatment of in situ cancer of the uterine cervix","volume":"10","author":"Sideri","year":"1994","journal-title":"J Gynecol Surg"},{"issue":"(1)","key":"10.1016\/j.ijgo.2015.07.026-BIB0190|rf0175","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.ygyno.2011.09.006","article-title":"Fertility-sparing treatment in younger women with adenocarcinoma in situ of the cervix","volume":"124","author":"van Hanegem","year":"2012","journal-title":"Gynecol Oncol"},{"issue":"(1)","key":"10.1016\/j.ijgo.2015.07.026-BIB0195|rf0180","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1006\/gyno.1998.5300","article-title":"A comparison between loop electrosurgical excision procedure and cold knife conization for treatment of cervical dysplasia: residual disease in a subsequent hysterectomy specimen","volume":"73","author":"Huang","year":"1999","journal-title":"Gynecol Oncol"},{"issue":"(3)","key":"10.1016\/j.ijgo.2015.07.026-BIB0200|rf0185","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1111\/j.1479-828X.1985.tb00645.x","article-title":"The diagnosis, treatment and complications of cervical intraepithelial neoplasia--experience at the Royal Hospital for Women, Sydney, during the years 1972-1982","volume":"25","author":"Seshadri","year":"1985","journal-title":"Aust N Z J Obstet Gynaecol"},{"issue":"(6)","key":"10.1016\/j.ijgo.2015.07.026-BIB0205|rf0190","first-page":"558","article-title":"Complications, sequelae and outcome of cervical conization: evaluation of three surgical techniques [in French]","volume":"31","author":"Brun","year":"2002","journal-title":"J Gynecol Obstet Biol Reprod (Paris)"},{"issue":"(3)","key":"10.1016\/j.ijgo.2015.07.026-BIB0210|rf0195","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/j.1471-0528.2009.02438.x","article-title":"After conisation of the cervix, the perinatal mortality as a result of preterm delivery increases in subsequent pregnancy","volume":"117","author":"Ortoft","year":"2010","journal-title":"BJOG"}],"container-title":["International Journal of Gynecology & Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S002072921500689X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S002072921500689X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2Fj.ijgo.2015.07.026","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2Fj.ijgo.2015.07.026","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1016\/j.ijgo.2015.07.026\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T21:35:37Z","timestamp":1567373737000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1016\/j.ijgo.2015.07.026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,28]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijgo.2015.07.026","archive":["Portico"],"relation":{},"ISSN":["0020-7292"],"issn-type":[{"value":"0020-7292","type":"print"}],"subject":[],"published":{"date-parts":[[2015,11,28]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Systematic reviews and meta-analyses of benefits and harms of cryotherapy, LEEP, and cold knife conization to treat cervical intraepithelial neoplasia","name":"articletitle","label":"Article Title"},{"value":"International Journal of Gynecology & Obstetrics","name":"journaltitle","label":"Journal Title"},{"value":"http:\/\/dx.doi.org\/10.1016\/j.ijgo.2015.07.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd.","name":"copyright","label":"Copyright"}]}}