{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T05:37:47Z","timestamp":1740116267335,"version":"3.37.3"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T00:00:00Z","timestamp":1462320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T00:00:00Z","timestamp":1462320000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["ijgo.org","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the association between polycystic ovarian morphology (PCOM) and thyroperoxidase antibody level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study was undertaken of women aged 15\u201349 years living in one of four provinces in Iran recruited between February 2009 and November 2010. Eligible women did not have hirsutism and were eumenorrheic. All participants underwent a comprehensive interview, clinical examination, blood sampling, and ultrasonographic assessment. The serum concentration of thyroperoxidase antibodies was compared between women with and without PCOM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 491 participants, 74 (15.1%) had PCOM. In total, 11 (14.9%) women with PCOM and 61 (14.6%) women with normal morphology tested positive for thyroperoxidase antibodies. The serum concentration of thyroperoxidase antibodies was higher among women with PCOM (48.45 \u00b1 135.74 IU\/mL) than among those with normal ovarian morphology (37.99 \u00b1 96.49 IU\/mL), but the difference was not significant (<jats:italic>P<\/jats:italic> = 0.42).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Thyroperoxidase antibody levels were higher in Iranian women with PCOM than in women with normal morphology, although the difference was not significant. Larger longitudinal studies are needed to investigate whether the treatment of thyroid disorders can prevent the development of PCOM.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.ijgo.2016.01.016","type":"journal-article","created":{"date-parts":[[2016,5,5]],"date-time":"2016-05-05T12:28:18Z","timestamp":1462451298000},"page":"197-201","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Thyroperoxidase antibodies and polycystic ovarian morphology"],"prefix":"10.1002","volume":"134","author":[{"given":"Fahimeh","family":"Ramezani Tehrani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahnaz","family":"Bahri Khomami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atieh","family":"Amouzegar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fereidoun","family":"Azizi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,4]]},"reference":[{"issue":"3","key":"e_1_2_7_2_2","first-page":"995","article-title":"Normal ovulatory women with polycystic ovaries have hyperandrogenic pituitary\u2010ovarian responses to gonadotropin\u2010releasing hormone\u2010agonist testing","volume":"85","author":"Chang P.L.","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2007.02752.x"},{"issue":"6","key":"e_1_2_7_4_2","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2014.02.022","article-title":"Ovarian morphology assessed by magnetic resonance imaging in women with and without polycystic ovary syndrome and associations with antimullerian hormone, free testosterone, and glucose disposal rate","volume":"101","author":"Leonhardt H.","year":"2014","journal-title":"Fertil Steril"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-0839"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2010.217"},{"issue":"12","key":"e_1_2_7_7_2","first-page":"1031","article-title":"Antithyroid peroxidase antibodies in women with polycystic ovary syndrome","volume":"11","author":"Salehpour S.","year":"2013","journal-title":"Iran J Reprod Med"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.05.063"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2013.03.003"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2009.01.056"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2010.06.008"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1500363"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.4103\/2230-8210.109714"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-09-1012"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2013.09.007"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2004.03.004"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2011.08.001"},{"issue":"2","key":"e_1_2_7_18_2","doi-asserted-by":"crossref","first-page":"145","DOI":"10.4103\/0256-4947.77500","article-title":"Effect of thyroid hormone replacement therapy on ovarian volume and androgen hormones in patients with untreated primary hypothyroidism","volume":"31","author":"Muderris I.I.","year":"2011","journal-title":"Ann Saudi Med"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-9-39"},{"issue":"6","key":"e_1_2_7_20_2","doi-asserted-by":"crossref","first-page":"982","DOI":"10.4103\/2230-8210.103006","article-title":"Association of polycystic ovary syndrome and Graves' disease: is autoimmunity the link between the two diseases","volume":"16","author":"Nisar S.","year":"2012","journal-title":"Indian J Endocrinol Metab"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2011.04042.x"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-031600"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/jdi.12040"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.954"},{"issue":"1","key":"e_1_2_7_25_2","first-page":"160","article-title":"The prevalence of polycystic ovary morphology among women attending a new teaching hospital in southern Nigeria","volume":"18","author":"Ogueh O.","year":"2014","journal-title":"Afr J Reprod Health"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/848403"}],"container-title":["International Journal of Gynecology &amp; 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