{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:05:55Z","timestamp":1790089555319,"version":"4.0.1"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,12,2]],"date-time":"2016-12-02T00:00:00Z","timestamp":1480636800000},"content-version":"vor","delay-in-days":31,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["ijgo.org","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare the efficacy of thermal balloon ablation (TBA) with that of vaginal hysterectomy in the treatment of leiomyoma\u2010induced heavy menstrual bleeding (HMB).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An open\u2010label randomized controlled trial was conducted between November 1, 2012, and October 31, 2014, in a tertiary care hospital in Delhi, India. Eligible women with HMB (aged \u2265 40 years, uterus size \u2264 14 weeks of pregnancy, leiomyoma \u2264 5 cm, uterocervical length \u2264 12 cm) were randomly assigned (1:1) to undergo TBA or vaginal hysterectomy using computer\u2010generated random number tables. The primary outcome was the number of women in the TBA group with HMB 6 months after surgery. Analyses were by intention to treat.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Each group contained 20 women. No women in the TBA group had HMB at 6 months. Nineteen women were amenorrheic by 6 months and one was hypomenorrheic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>TBA can replace vaginal hysterectomy in some perimenopausal women with uterine leiomyomas.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Clinical Trials Registry India: CTRI\/2016\/07\/007119.<\/jats:bold>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijgo.2016.04.020","type":"journal-article","created":{"date-parts":[[2016,8,5]],"date-time":"2016-08-05T20:47:16Z","timestamp":1470430036000},"page":"140-144","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Randomized controlled trial of thermal balloon ablation versus vaginal hysterectomy for leiomyoma\u2010induced heavy menstrual bleeding"],"prefix":"10.1002","volume":"135","author":[{"given":"Prachi","family":"Jain","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shalini","family":"Rajaram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bindiya","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neerja","family":"Goel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Himsweta","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,12,2]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c3929"},{"issue":"2","key":"e_1_2_6_3_2","first-page":"243","article-title":"Low\u2010dose mifepristone for uterine leiomyomata","volume":"101","author":"Eisinger H.S.","year":"2003","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000232618.26261.75"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318299a6cf"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.4103\/0970-0218.42065"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/279273"},{"issue":"4","key":"e_1_2_6_8_2","first-page":"437","article-title":"Alternatives to hysterectomy: focus on global endometrial ablation, uterine fibroid embolization, magnetic resonance\u2010guided focused ultrasound","volume":"18","author":"Stovall D.W.","year":"2011","journal-title":"Menopause"},{"issue":"4","key":"e_1_2_6_9_2","first-page":"305","article-title":"Long term results in treatment of menorrhagia and hypermenorrhea with a thermal balloon endometrial ablation technique","volume":"6","author":"Mettler L.","year":"2002","journal-title":"JSLS"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1067\/S0002-9378(03)00403-4"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000052908"},{"key":"e_1_2_6_12_2","first-page":"CD000329","article-title":"Endometrial resection and ablation versus hysterectomy for heavy menstrual bleeding","volume":"11","author":"Fergusson R.J.","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-200106000-00020"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-6-99"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000292083.97478.38"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-3804(00)80036-5"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(03)00160-X"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2003.10.010"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2011.01596.x"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.5468\/OGS.2013.56.1.36"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2015.02.035"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2012.03484.x"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1159\/000316261"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.4293\/JSLS.2014.00325"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2015.11.015"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2014.11.011"}],"container-title":["International Journal of Gynecology &amp; 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