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Mater. Adv."},{"key":"10.1016\/j.ijheh.2026.114855_bib65","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1021\/es5002105","article-title":"Identifying small molecules via high resolution mass spectrometry: communicating confidence","volume":"48","author":"Schymanski","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ijheh.2026.114855_bib66","doi-asserted-by":"crossref","first-page":"16918","DOI":"10.1021\/acs.est.3c04855","article-title":"Per- and Polyfluoroalkyl Substances (PFAS) in PubChem: 7 million and growing","volume":"57","author":"Schymanski","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ijheh.2026.114855_bib67","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1038\/s41370-023-00578-2","article-title":"Practical application guide for the discovery of novel PFAS in environmental samples using high resolution mass spectrometry","volume":"33","author":"Strynar","year":"2023","journal-title":"J. Expo. Sci. 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