{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:08:20Z","timestamp":1759104500004},"reference-count":38,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":1178,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2010,6]]},"DOI":"10.1016\/j.ijid.2009.07.025","type":"journal-article","created":{"date-parts":[[2009,12,7]],"date-time":"2009-12-07T14:44:34Z","timestamp":1260197074000},"page":"e506-e510","source":"Crossref","is-referenced-by-count":24,"title":["Bartonella bacilliformis, endemic pathogen of the Andean region, is intrinsically resistant to quinolones"],"prefix":"10.1016","volume":"14","author":[{"given":"Luis J.","family":"del Valle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lidia","family":"Flores","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha","family":"Vargas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Garc\u00eda-de-la-Guarda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth L.","family":"Quispe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoila B.","family":"Iba\u00f1ez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D\u00e9bora","family":"Alvarado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Ram\u00edrez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joaquim","family":"Ruiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijid.2009.07.025_bib1","doi-asserted-by":"crossref","first-page":"174","DOI":"10.4269\/ajtmh.1997.57.174","article-title":"Bartonellosis in Ecuador: serosurvey and current status of cutaneous verrucous disease","volume":"57","author":"Amano","year":"1997","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.ijid.2009.07.025_bib2","doi-asserted-by":"crossref","first-page":"122","DOI":"10.20453\/rmh.v17i3.869","article-title":"Bartonelosis aguda en ni\u00f1os: estudio de 32 casos en el Instituto Especializado de Salud del Ni\u00f1o y el Hospital Nacional Cayetano Heredia (Per\u00edodo 1993-2003)","volume":"17","author":"Bre\u00f1a Ch\u00e1vez","year":"2006","journal-title":"Rev Med Hered"},{"key":"10.1016\/j.ijid.2009.07.025_bib3","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1086\/344054","article-title":"Epidemiology of endemic Bartonella bacilliformis: a prospective cohort study in a Peruvian mountain valley community","volume":"186","author":"Chamberlin","year":"2001","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ijid.2009.07.025_bib4","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1590\/S1413-86702004000500001","article-title":"Bartonelosis (Carrion's disease) in the pediatric population of Peru: an overview and update","volume":"8","author":"Huarcaya","year":"2004","journal-title":"Braz J Infect Dis"},{"key":"10.1016\/j.ijid.2009.07.025_bib5","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1128\/JCM.01207-07","article-title":"Isolation and characterization of Bartonella bacilliformis from an expatriate Ecuadorian","volume":"46","author":"Lydy","year":"2008","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijid.2009.07.025_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0891-5520(05)70215-4","article-title":"Bartonellosis\u2014new and old","volume":"14","author":"Magui\u00f1a","year":"2000","journal-title":"Infect Dis Clin North Am"},{"key":"10.1016\/j.ijid.2009.07.025_bib7","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1086\/322614","article-title":"Bartonellosis (Carrion's disease) in the modern era","volume":"33","author":"Magui\u00f1a","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijid.2009.07.025_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1574-6968.1996.tb08501.x","article-title":"Bartonella bacilliformis: dangerous pathogen slowly emerging from deep background","volume":"144","author":"Ihler","year":"1996","journal-title":"FEMS Microbiol Lett"},{"key":"10.1016\/j.ijid.2009.07.025_bib9","unstructured":"MINSA (Ministerio de Salud, Per\u00fa). Normas t\u00e9cnicas para el diagn\u00f3stico y atenci\u00f3n curativa de la bartonellosis o enfermedad de Carrion en el Per\u00fa. Lima, Peru: MINSA; 2003."},{"key":"10.1016\/j.ijid.2009.07.025_bib10","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1128\/AAC.48.6.1921-1933.2004","article-title":"Recommendations for treatment of human infections caused by Bartonella species","volume":"48","author":"Rolain","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijid.2009.07.025_bib11","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.medmal.2006.07.020","article-title":"13-Antibiotic therapy of community-acquired pneumonia (CAP) caused by atypical agents","volume":"36","author":"Roig","year":"2006","journal-title":"Med Mal Infect"},{"key":"10.1016\/j.ijid.2009.07.025_bib12","unstructured":"MINSA (Ministerio de Salud, Per\u00fa). Norma t\u00e9cnica de salud para la atenci\u00f3n de la bartonelosis o enfermedad de Carri\u00f3n en el Per\u00fa. NTS N\u00b0 048-MINSA\/DGSP-V.01. Lima, Peru: MINSA; 2006."},{"key":"10.1016\/j.ijid.2009.07.025_bib13","first-page":"188","article-title":"Terapia antibi\u00f3tica para el manejo de la bartonelosis o enfermedad de Carri\u00f3n en el Per\u00fa","volume":"23","author":"Tarazona","year":"2006","journal-title":"Rev Peru Med Exp Salud Publica"},{"key":"10.1016\/j.ijid.2009.07.025_bib14","series-title":"Epidemiolog\u00eda de la enfermedad de Carri\u00f3n y las bases para su control: nuevos paradigmas","author":"Pachas","year":"2000"},{"key":"10.1016\/j.ijid.2009.07.025_bib15","first-page":"3","article-title":"Resumen del primer caso de bartonelosis identificado en Lima procedente de Santa Eulalia","volume":"38","author":"Anonymous","year":"2006","journal-title":"Boletin del Instituto Nacional de Salud"},{"key":"10.1016\/j.ijid.2009.07.025_bib16","doi-asserted-by":"crossref","first-page":"3801","DOI":"10.1128\/AAC.00638-08","article-title":"Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France","volume":"52","author":"Cattoir","year":"2008","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijid.2009.07.025_bib17","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1093\/jac\/dkm204","article-title":"Multiplex PCR for detection of plasmid-mediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates","volume":"60","author":"Cattoir","year":"2007","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijid.2009.07.025_bib18","doi-asserted-by":"crossref","first-page":"3953","DOI":"10.1128\/AAC.00915-06","article-title":"Prevalence in the United States of aac(6\u2019)-Ib-cr encoding a ciprofloxacin-modifying enzyme","volume":"50","author":"Park","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijid.2009.07.025_bib19","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1093\/jac\/dkg222","article-title":"Mechanisms of resistance to quinolones: target alterations, decreased accumulation and DNA gyrase protection","volume":"51","author":"Ruiz","year":"2003","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijid.2009.07.025_bib20","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1021\/jm01240a021","article-title":"1,8-Naphthyridine derivatives: a new class of chemotherapy agents","volume":"5","author":"Lesher","year":"1962","journal-title":"J Med Pharm Chem"},{"key":"10.1016\/j.ijid.2009.07.025_bib21","doi-asserted-by":"crossref","first-page":"697","DOI":"10.7326\/0003-4819-126-9-199705010-00004","article-title":"Treatment of shigellosis: V. Comparison of azithromycin and ciprofloxacin","volume":"126","author":"Khan","year":"1997","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ijid.2009.07.025_bib22","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0732-8893(01)00357-1","article-title":"High prevalence of nalidixic acid resistant, ciprofloxacin susceptible phenotype among clinical isolates of Escherichia coli and other Enterobacteriaceae","volume":"42","author":"Ruiz","year":"2002","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.ijid.2009.07.025_bib23","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1086\/516128","article-title":"Quinolone-resistant Salmonella typhi in Viet Nam: molecular basis of resistance and clinical response to treatment","volume":"25","author":"Wain","year":"1997","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijid.2009.07.025_bib24","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1128\/AAC.47.1.383-386.2003","article-title":"gyrA mutations in ciprofloxacin-resistant Bartonella bacilliformis strains obtained in vitro","volume":"47","author":"Minnick","year":"2003","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijid.2009.07.025_bib25","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1093\/jac\/44.6.735","article-title":"Mechanisms involved in the development of resistance to fluoroquinolones in Escherichia coli strains","volume":"44","author":"Tavio","year":"1999","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijid.2009.07.025_bib26","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1128\/AAC.44.6.1731-1733.2000","article-title":"Quinolone resistance in enterotoxigenic Escherichia coli causing diarrhea in travelers to India in comparison with travelers to other geographical areas","volume":"44","author":"Vila","year":"2000","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijid.2009.07.025_bib27","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1099\/0022-1317-50-11-996","article-title":"Susceptibility patterns of enteroaggregative Escherichia coli associated to traveller's diarrhoea. Emergence of quinolone resistance","volume":"50","author":"Vila","year":"2001","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.ijid.2009.07.025_bib28","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1002\/cbic.200800041","article-title":"Mechanism of binding of fluoroquinolones to the quinolone resistance-determining region of DNA gyrase: towards an understanding of the molecular basis of quinolone resistance","volume":"9","author":"Madurga","year":"2008","journal-title":"ChembioChem"},{"key":"10.1016\/j.ijid.2009.07.025_bib29","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1093\/jac\/dkl341","article-title":"In vitro susceptibility of Bartonella species to 17 antimicrobial compounds: comparison of Etest and agar dilution","volume":"58","author":"D\u00f6rbecker","year":"2006","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijid.2009.07.025_bib30","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1093\/jac\/dki139","article-title":"Brevundimonas diminuta infections and its resistance to fluoroquinolones","volume":"55","author":"Han","year":"2005","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijid.2009.07.025_bib31","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.ijantimicag.2007.02.010","article-title":"In vitro antibacterial activity of tigecycline in comparison with doxycycline, ciprofloxacin and rifampicin against Brucella spp","volume":"30","author":"Turan","year":"2007","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.ijid.2009.07.025_bib32","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1093\/jac\/dkn094","article-title":"Heterogeneity of susceptibility to fluoroquinolones in Bartonella isolates from Australia reveals a natural mutation in gyrA","volume":"61","author":"Angelakis","year":"2008","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijid.2009.07.025_bib33","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1128\/AAC.43.8.2090","article-title":"In vitro susceptibilities of four Bartonella bacilliformis strains to 30 antibiotic compounds","volume":"43","author":"Sobraques","year":"1999","journal-title":"Antimicrob Agents Chemother"},{"issue":"Suppl S1","key":"10.1016\/j.ijid.2009.07.025_bib34","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1093\/jac\/dkg208","article-title":"The quinolones: decades of development and use","volume":"51","author":"Emmerson","year":"2003","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijid.2009.07.025_bib35","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1086\/503177","article-title":"Outbreak caused by Acinetobacter strain RUH 1139 in an intensive care unit","volume":"27","author":"Salazar de Vegas","year":"2006","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.ijid.2009.07.025_bib36","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0022-2836(82)90515-0","article-title":"A simple method for displaying the hydropathic character of a protein","volume":"157","author":"Kyte","year":"1982","journal-title":"J Mol Biol"},{"key":"10.1016\/j.ijid.2009.07.025_bib37","series-title":"The proteomics protocols handbook","first-page":"571","article-title":"Protein identification and analysis tools on the ExPASy server","author":"Gasteiger","year":"2005"},{"key":"10.1016\/j.ijid.2009.07.025_bib38","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1093\/jac\/dkm105","article-title":"Molecular mechanisms of resistance to antibiotics in Bartonella bacilliformis","volume":"59","author":"Biswas","year":"2007","journal-title":"J Antimicrob Chemother"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971209003397?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971209003397?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T08:49:36Z","timestamp":1558687776000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971209003397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6]]},"references-count":38,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["S1201971209003397"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2009.07.025","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2010,6]]}}}