{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T11:22:36Z","timestamp":1790680956940,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,11,5]],"date-time":"2019-11-05T00:00:00Z","timestamp":1572912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["17H06394"],"award-info":[{"award-number":["17H06394"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["18K08426"],"award-info":[{"award-number":["18K08426"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["TW"],"award-info":[{"award-number":["TW"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.ijid.2019.11.003","type":"journal-article","created":{"date-parts":[[2019,11,15]],"date-time":"2019-11-15T11:45:06Z","timestamp":1573818306000},"page":"22-31","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Collagen adhesion gene is associated with bloodstream infections caused by methicillin-resistant Staphylococcus aureus"],"prefix":"10.1016","volume":"91","author":[{"given":"Yasunori","family":"Iwata","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Satou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kengo","family":"Furuichi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikuko","family":"Yoneda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuhiro","family":"Matsumura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Yutani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukako","family":"Fujinaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Hase","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidetoshi","family":"Morita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiko","family":"Ohta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuko","family":"Senda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukiko","family":"Sakai-Takemori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taizo","family":"Wada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Fujita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taito","family":"Miyake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruka","family":"Yasuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norihiko","family":"Sakai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Kitajima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadashi","family":"Toyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuyuki","family":"Shinozaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Sagara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taro","family":"Miyagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akinori","family":"Hara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miho","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasutaka","family":"Kamikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuho","family":"Ikeo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeyuki","family":"Shichino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Ueha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Nakajima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kouji","family":"Matsushima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuichi","family":"Kaneko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Wada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijid.2019.11.003_bib0005","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1093\/jac\/dku114","article-title":"Analysis of Staphylococcus aureus clinical isolates with reduced susceptibility to ceftaroline: an epidemiological and structural perspective","volume":"69","author":"Alm","year":"2014","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijid.2019.11.003_bib0010","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1111\/mmi.12682","article-title":"Evolution of hypervirulence by a MRSA clone through acquisition of a transposable element","volume":"93","author":"Benson","year":"2014","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.ijid.2019.11.003_bib0015","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s10096-016-2601-4","article-title":"Population-based epidemiology of Staphylococcus aureus bloodstream infection: clonal complex 30 genotype is associated with mortality","volume":"35","author":"Blomfeldt","year":"2016","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.ijid.2019.11.003_bib0020","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/978-1-62703-664-1_12","article-title":"Investigation of biofilm formation in clinical isolates of Staphylococcus aureus","volume":"1085","author":"Cassat","year":"2014","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.ijid.2019.11.003_bib0025","doi-asserted-by":"crossref","first-page":"39943","DOI":"10.1038\/srep39943","article-title":"Building a genetic risk model for bipolar disorder from genome-wide association data with random forest algorithm","volume":"7","author":"Chuang","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.ijid.2019.11.003_bib0030","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/nrmicro3161","article-title":"Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus","volume":"12","author":"Foster","year":"2014","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.ijid.2019.11.003_bib0035","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1086\/427806","article-title":"Risk factors for hematogenous complications of intravascular catheter-associated Staphylococcus aureus bacteremia","volume":"40","author":"Fowler","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijid.2019.11.003_bib0040","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1128\/JCM.43.3.1149-1157.2005","article-title":"Rapid identification of staphylococcal strains from positive-testing blood culture bottles by internal transcribed spacer PCR followed by microchip gel electrophoresis","volume":"43","author":"Fujita","year":"2005","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijid.2019.11.003_bib0045","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1126\/science.1182395","article-title":"Evolution of MRSA during hospital transmission and intercontinental spread","volume":"327","author":"Harris","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.ijid.2019.11.003_bib0050","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/S1473-3099(12)70268-2","article-title":"Whole-genome sequencing for analysis of an outbreak of meticillin-resistant Staphylococcus aureus: a descriptive study","volume":"13","author":"Harris","year":"2013","journal-title":"Lancet Infect Dis"},{"issue":"October (10)","key":"10.1016\/j.ijid.2019.11.003_bib0055","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1007\/s10096-017-2999-3","article-title":"Down-regulation of the two-component system and cell-wall biosynthesis-related genes was associated with the reversion to daptomycin susceptibility in daptomycin non-susceptible methicillin-resistant Staphylococcus aureus","volume":"36","author":"Iwata","year":"2017","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.ijid.2019.11.003_bib0060","series-title":"Japan Nosocomial Infections Surveillance (JANIS)","author":"JANIS","year":"2019"},{"key":"10.1016\/j.ijid.2019.11.003_bib0065","doi-asserted-by":"crossref","first-page":"20520","DOI":"10.1074\/jbc.M113.454462","article-title":"Collagen-binding microbial surface components recognizing adhesive matrix molecule (MSCRAMM) of Gram-positive bacteria inhibit complement activation via the classical pathway","volume":"288","author":"Kang","year":"2013","journal-title":"J Biol Chem"},{"key":"10.1016\/j.ijid.2019.11.003_bib0070","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1056\/NEJMoa1109910","article-title":"Rapid whole-genome sequencing for investigation of a neonatal MRSA outbreak","volume":"366","author":"K\u00f6ser","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijid.2019.11.003_bib0075","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1056\/NEJMoa1109910","article-title":"Rapid whole-genome sequencing for investigation of a neonatal MRSA outbreak","volume":"366","author":"K\u00f6ser","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijid.2019.11.003_bib0080","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1101\/gr.165415.113","article-title":"Predicting the virulence of MRSA from its genome sequence","volume":"24","author":"Laabei","year":"2014","journal-title":"Genome Res"},{"key":"10.1016\/j.ijid.2019.11.003_bib0085","doi-asserted-by":"crossref","first-page":"2365","DOI":"10.1128\/JCM.00262-14","article-title":"Bacterial whole-genome sequencing revisited: portable, scalable, and standardized analysis for typing and detection of virulence and antibiotic resistance genes","volume":"52","author":"Leopold","year":"2014","journal-title":"J Clin Microbiol"},{"issue":"February","key":"10.1016\/j.ijid.2019.11.003_bib0090","doi-asserted-by":"crossref","first-page":"6255","DOI":"10.1038\/ncomms7255","article-title":"Botulinum toxin A complex exploits intestinal M cells to enter the host and exert neurotoxicity","volume":"6","author":"Matsumura","year":"2015","journal-title":"Nat Commun"},{"key":"10.1016\/j.ijid.2019.11.003_bib0095","doi-asserted-by":"crossref","first-page":"4349","DOI":"10.1128\/JCM.05017-11","article-title":"DNA microarray genotyping and virulence and antimicrobial resistance gene profiling of methicillin-resistant Staphylococcus aureus bloodstream isolates from renal patients","volume":"49","author":"McNicholas","year":"2011","journal-title":"J Clin Microbiol"},{"issue":"October (5)","key":"10.1016\/j.ijid.2019.11.003_bib0100","article-title":"Temporal and stochastic control of Staphylococcus aureus biofilm development","volume":"5","author":"Moormeier","year":"2014","journal-title":"MBio"},{"key":"10.1016\/j.ijid.2019.11.003_bib0105","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1093\/infdis\/jir389","article-title":"Methicillin-susceptible Staphylococcus aureus endocarditis isolates are associated with clonal complex 30 genotype and a distinct repertoire of enterotoxins and adhesins","volume":"204","author":"Nienaber","year":"2011","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ijid.2019.11.003_bib0110","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.1093\/jac\/dku128","article-title":"Zero tolerance for healthcare-associated MRSA bacteraemia: is it realistic?","volume":"69","author":"T\u00f6r\u00f6k","year":"2014","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijid.2019.11.003_bib0115","doi-asserted-by":"crossref","first-page":"5650","DOI":"10.1128\/JCM.42.12.5650-5657.2004","article-title":"Epidemiology and typing of Staphylococcus aureus strains isolated from bloodstream infections","volume":"42","author":"van der Mee-Marquet","year":"2004","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijid.2019.11.003_bib0120","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1086\/595738","article-title":"Phenotypic and genotypic characteristics of persistent methicillin-resistant Staphylococcus aureus bacteremia in vitro and in an experimental endocarditis model","volume":"199","author":"Xiong","year":"2009","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ijid.2019.11.003_bib0125","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1086\/595738","article-title":"Phenotypic and genotypic characteristics of persistent methicillin-resistant Staphylococcus aureus bacteremia in vitro and in an experimental endocarditis model","volume":"199","author":"Xiong","year":"2009","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ijid.2019.11.003_bib0130","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.diagmicrobio.2012.08.015","article-title":"Virulence gene profiling and molecular characterization of hospital-acquired Staphylococcus aureus isolates associated with bloodstream infection","volume":"74","author":"Yu","year":"2012","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.ijid.2019.11.003_bib0135","doi-asserted-by":"crossref","first-page":"45195","DOI":"10.1038\/srep45195","article-title":"Several microRNAs could predict survival in patients with hepatitis B-related liver cancer","volume":"7","author":"Zhen","year":"2017","journal-title":"Sci Rep"},{"issue":"December (24)","key":"10.1016\/j.ijid.2019.11.003_bib0140","doi-asserted-by":"crossref","first-page":"4224","DOI":"10.1038\/sj.emboj.7600888","article-title":"A \u2018Collagen Hug\u2019 model for Staphylococcus aureus CNA binding to collagen","volume":"24","author":"Zong","year":"2005","journal-title":"EMBO J"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971219304424?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971219304424?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T17:11:21Z","timestamp":1778519481000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971219304424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":28,"alternative-id":["S1201971219304424"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2019.11.003","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Collagen adhesion gene is associated with bloodstream infections caused by methicillin-resistant Staphylococcus aureus","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2019.11.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}]}}