{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:16:53Z","timestamp":1790745413956,"version":"4.1.0"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,7,29]],"date-time":"2020-07-29T00:00:00Z","timestamp":1595980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.ijid.2020.07.062","type":"journal-article","created":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T16:14:27Z","timestamp":1596816867000},"page":"382-385","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Falciparum malaria-induced secondary hemophagocytic lymphohistiocytosis successfully treated with ruxolitinib"],"prefix":"10.1016","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6906-2598","authenticated-orcid":false,"given":"Andr\u00e9","family":"Fuchs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Martin","family":"Orth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Germing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Kondakci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martha","family":"Holtfreter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6755-4492","authenticated-orcid":false,"given":"Torsten","family":"Feldt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1626-4855","authenticated-orcid":false,"given":"Bj\u00f6rn Erik-Ole","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dieter","family":"H\u00e4ussinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.ijid.2020.07.062_bib0005","doi-asserted-by":"crossref","first-page":"e630","DOI":"10.1016\/S2352-3026(19)30156-5","article-title":"Ruxolitinib in adult patients with secondary haemophagocytic lymphohistiocytosis: an open-label, single-centre, pilot trial","volume":"6","author":"Ahmed","year":"2019","journal-title":"Lancet Haematol"},{"key":"10.1016\/j.ijid.2020.07.062_bib0010","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1182\/asheducation-2015.1.177","article-title":"Pathophysiology and epidemiology of hemophagocytic lymphohistiocytosis","volume":"2015","author":"Allen","year":"2015","journal-title":"Hematol Am Soc Hematol Educ Program"},{"key":"10.1016\/j.ijid.2020.07.062_bib0015","doi-asserted-by":"crossref","DOI":"10.1179\/2046905514Y.0000000163","article-title":"Haemophagocytic lymphohistiocytosis: a cause of unresponsive malaria in a 5-year-old girl","author":"Bhagat","year":"2014","journal-title":"Paediatr Int Child Health"},{"issue":"13","key":"10.1016\/j.ijid.2020.07.062_bib0020","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1182\/blood-2015-12-684399","article-title":"Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis","volume":"127","author":"Das","year":"2016","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.ijid.2020.07.062_bib0025","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1186\/s12936-016-1529-6","article-title":"Performance and time to become negative after treatment of three malaria rapid diagnostic tests in low and high malaria transmission settings","volume":"15","author":"Grandesso","year":"2016","journal-title":"Malar J"},{"issue":"8","key":"10.1016\/j.ijid.2020.07.062_bib0030","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.medmal.2017.07.005","article-title":"Hemophagocytic lymphohistiocytosis associated with Plasmodium falciparum","volume":"47","author":"Harioly Nirina","year":"2017","journal-title":"Med Mal Infect"},{"issue":"2","key":"10.1016\/j.ijid.2020.07.062_bib0035","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1002\/pbc.21039","article-title":"HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis","volume":"48","author":"Henter","year":"2007","journal-title":"Pediatr Blood Cancer"},{"issue":"7","key":"10.1016\/j.ijid.2020.07.062_bib0040","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1007\/s10875-017-0439-x","article-title":"A personalized diagnostic and treatment approach for macrophage activation syndrome and secondary hemophagocytic lymphohistiocytosis in adults","volume":"37","author":"Kumar","year":"2017","journal-title":"J Clin Immunol"},{"issue":"2","key":"10.1016\/j.ijid.2020.07.062_bib0045","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3109\/08977194.2012.660936","article-title":"Biology and significance of the JAK\/STAT signalling pathways","volume":"30","author":"Kiu","year":"2012","journal-title":"Growth Factors Chur Switz"},{"issue":"1","key":"10.1016\/j.ijid.2020.07.062_bib0050","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1182\/blood-2016-02-700013","article-title":"Therapeutic effect of JAK1\/2 blockade on the manifestations of hemophagocytic lymphohistiocytosis in mice","volume":"128","author":"Maschalidi","year":"2016","journal-title":"Blood"},{"issue":"9","key":"10.1016\/j.ijid.2020.07.062_bib0055","first-page":"817","article-title":"Hemophagocytic lymphohistiocytosis: pathogenesis, diagnosis, and management","volume":"58","author":"Morimoto","year":"2016","journal-title":"Pediatr Int Off J Jpn Pediatr Soc"},{"issue":"6","key":"10.1016\/j.ijid.2020.07.062_bib0060","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.4269\/ajtmh.2007.76.1016","article-title":"CLINICAL case report: falciparum malaria with hemophagocytic syndrome","volume":"76","author":"Ohnishi","year":"2007","journal-title":"Am J Trop Med Hyg"},{"issue":"9927","key":"10.1016\/j.ijid.2020.07.062_bib0065","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1016\/S0140-6736(13)61048-X","article-title":"Adult haemophagocytic syndrome","volume":"383","author":"Ramos-Casals","year":"2014","journal-title":"Lancet Lond Engl"},{"issue":"3","key":"10.1016\/j.ijid.2020.07.062_bib0070","doi-asserted-by":"crossref","first-page":"594","DOI":"10.4103\/0377-4929.85105","article-title":"Hemophagocytic syndrome associated with Plasmodium falciparum infection","volume":"54","author":"Vinoth","year":"2011","journal-title":"Indian J Pathol Microbiol"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971220306263?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971220306263?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T22:54:26Z","timestamp":1738450466000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971220306263"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":14,"alternative-id":["S1201971220306263"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2020.07.062","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Falciparum malaria-induced secondary hemophagocytic lymphohistiocytosis successfully treated with ruxolitinib","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2020.07.062","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}]}}