{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:59:02Z","timestamp":1789588742537,"version":"build-2803163510"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,9,7]],"date-time":"2020-09-07T00:00:00Z","timestamp":1599436800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100017610","name":"Shenzhen Science and Technology Innovation Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100017610","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.ijid.2020.09.015","type":"journal-article","created":{"date-parts":[[2020,9,11]],"date-time":"2020-09-11T01:38:57Z","timestamp":1599788337000},"page":"483-489","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":80,"special_numbering":"C","title":["Antibody-dependent enhancement of coronavirus"],"prefix":"10.1016","volume":"100","author":[{"given":"Jieqi","family":"Wen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongsong","family":"Ling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yarong","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boxuan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjie","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0343-2955","authenticated-orcid":false,"given":"Yizhou","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijid.2020.09.015_bib0005","doi-asserted-by":"crossref","first-page":"12479","DOI":"10.1073\/pnas.1106568108","article-title":"Ligation of Fc gamma receptor IIB inhibits antibody-dependent enhancement of dengue virus infection","volume":"108","author":"Chan","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.ijid.2020.09.015_bib0010","article-title":"Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility","author":"Chan","year":"2020","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijid.2020.09.015_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2020.102768","article-title":"Impact of immune enhancement on Covid-19 polyclonal hyperimmune globulin therapy and vaccine development","volume":"55","author":"de Alwis","year":"2020","journal-title":"EBioMedicine"},{"key":"10.1016\/j.ijid.2020.09.015_bib0020","doi-asserted-by":"crossref","first-page":"7045","DOI":"10.1128\/JVI.00433-14","article-title":"A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike protein","volume":"88","author":"Du","year":"2014","journal-title":"J Virol"},{"issue":"17","key":"10.1016\/j.ijid.2020.09.015_bib0025","doi-asserted-by":"crossref","first-page":"9490","DOI":"10.1073\/pnas.2004168117","article-title":"Effectiveness of convalescent plasma therapy in severe COVID-19 patients","volume":"117","author":"Duan","year":"2020","journal-title":"Proc Natl Acad Sci USA"},{"issue":"November (6)","key":"10.1016\/j.ijid.2020.09.015_bib0030","article-title":"Complement receptors in myeloid cell adhesion and phagocytosis","volume":"4","author":"Dustin","year":"2016","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.ijid.2020.09.015_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcv.2020.104388","article-title":"Current studies of convalescent plasma therapy for COVID-19 may underestimate risk of antibody-dependent enhancement","volume":"127","author":"Fleming","year":"2020","journal-title":"J Clin Virol"},{"key":"10.1016\/j.ijid.2020.09.015_bib0040","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1146\/annurev-micro-020518-115759","article-title":"Human coronavirus: host-pathogen interaction","volume":"73","author":"Fung","year":"2019","journal-title":"Annu Rev Microbiol"},{"key":"10.1016\/j.ijid.2020.09.015_bib0045","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1126\/science.abc1932","article-title":"Development of an inactivated vaccine candidate for SARS-CoV-2","author":"Gao","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.ijid.2020.09.015_bib0050","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1128\/JVI.76.6.2827-2834.2002","article-title":"Antibody-mediated enhancement of human immunodeficiency virus type 1 infectivity is determined by the structure of gp120 and depends on modulation of the gp120-CCR5 interaction","volume":"76","author":"Guillon","year":"2002","journal-title":"J Virol"},{"issue":"6","key":"10.1016\/j.ijid.2020.09.015_bib0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41577-020-0323-4","article-title":"COVID-19 vaccine design: the Janus face of immune enhancement","volume":"20","author":"Hotez","year":"2020","journal-title":"Nat Rev Immunol"},{"issue":"7799","key":"10.1016\/j.ijid.2020.09.015_bib0060","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/d41586-020-00751-9","article-title":"Don\u2019t rush to deploy COVID-19 vaccines and drugs without sufficient safety guarantees","volume":"579","author":"Jiang","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.ijid.2020.09.015_bib0065","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.vaccine.2006.08.011","article-title":"Antibodies against trimeric S glycoprotein protect hamsters against SARS-CoV challenge despite their capacity to mediate FcgammaRII-dependent entry into B cells in vitro","volume":"25","author":"Kam","year":"2007","journal-title":"Vaccine"},{"key":"10.1016\/j.ijid.2020.09.015_bib0070","series-title":"Southern Weekly","author":"Li","year":"2020"},{"issue":"4","key":"10.1016\/j.ijid.2020.09.015_bib0075","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.123158","article-title":"Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection","volume":"4","author":"Liu","year":"2019","journal-title":"JCI Insight"},{"key":"10.1016\/j.ijid.2020.09.015_bib0080","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s12250-018-0009-2","article-title":"Evaluation of antibody-dependent enhancement of SARS-CoV infection in rhesus macaques immunized with an inactivated SARS-CoV vaccine","volume":"33","author":"Luo","year":"2018","journal-title":"Virol Sin"},{"key":"10.1016\/j.ijid.2020.09.015_bib0085","doi-asserted-by":"crossref","first-page":"13819","DOI":"10.1073\/pnas.202415999","article-title":"Suppression of lipopolysaccharide-induced antiviral transcription factor (STAT-1 and NF-kappa B) complexes by antibody-dependent enhancement of macrophage infection by Ross River virus","volume":"99","author":"Mahalingam","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.ijid.2020.09.015_bib0090","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.coviro.2019.02.002","article-title":"Structural perspectives of antibody-dependent enhancement of infection of dengue virus","volume":"36","author":"Morrone","year":"2019","journal-title":"Curr Opin Virol"},{"key":"10.1016\/j.ijid.2020.09.015_bib0095","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3389\/fimmu.2018.00205","article-title":"Pathogenicity and viral shedding of MERS-CoV in immunocompromised rhesus macaques","volume":"9","author":"Prescott","year":"2018","journal-title":"Front Immunol"},{"issue":"8","key":"10.1016\/j.ijid.2020.09.015_bib0100","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1073\/pnas.0307140101","article-title":"Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association","volume":"101","author":"Sui","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"issue":"6","key":"10.1016\/j.ijid.2020.09.015_bib0105","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1292\/jvms.18-0702","article-title":"Pathogenesis of oral type I feline infectious peritonitis virus (FIPV) infection: antibody-dependent enhancement infection of cats with type I FIPV via the oral route","volume":"81","author":"Takano","year":"2019","journal-title":"J Vet Med Sci"},{"issue":"4\u20135","key":"10.1016\/j.ijid.2020.09.015_bib0110","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.micinf.2020.03.002","article-title":"Molecular basis of COVID-19 relationships in different species: a one health perspective","volume":"22","author":"Tilocca","year":"2020","journal-title":"Microbe Infect"},{"issue":"1","key":"10.1016\/j.ijid.2020.09.015_bib0115","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1111\/imr.12367","article-title":"Fc receptors in antibody-dependent enhancement of viral infections","volume":"268","author":"Taylor","year":"2015","journal-title":"Immunol Rev"},{"issue":"4\u20135","key":"10.1016\/j.ijid.2020.09.015_bib0120","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.micinf.2020.05.013","article-title":"Immunoinformatic analysis of the SARS-CoV-2 envelope protein as a strategy to assess crossprotection against COVID-19","volume":"22","author":"Tilocca","year":"2020","journal-title":"Microbe Infect"},{"issue":"14","key":"10.1016\/j.ijid.2020.09.015_bib0125","doi-asserted-by":"crossref","first-page":"8102","DOI":"10.1128\/JVI.00649-14","article-title":"Antibody-mediated enhancement of parvovirus B19 uptake into endothelial cells mediated by a receptor for complement factor C1q","volume":"88","author":"von Kietzell","year":"2014","journal-title":"J Virol"},{"issue":"5","key":"10.1016\/j.ijid.2020.09.015_bib0130","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.02015-19","article-title":"Molecular mechanism for antibodydependent enhancement of coronavirus entry","volume":"94","author":"Wan","year":"2020","journal-title":"J Virol"},{"issue":"5","key":"10.1016\/j.ijid.2020.09.015_bib0135","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1021\/acsinfecdis.6b00006","article-title":"Immunodominant SARS coronavirus epitopes in humans elicited both enhancing and neutralizing effects on infection in non-human primates","volume":"2","author":"Wang","year":"2016","journal-title":"ACS Infect Dis"},{"key":"10.1016\/j.ijid.2020.09.015_bib0140","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.bbrc.2014.07.090","article-title":"Antibody-dependent SARS coronavirus infection is mediated by antibodies against spike proteins","volume":"451","author":"Wang","year":"2014","journal-title":"Biochem Biophys Res Commun"},{"issue":"10169","key":"10.1016\/j.ijid.2020.09.015_bib0145","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/S0140-6736(18)32560-1","article-title":"Dengue","volume":"393","author":"Wilder-Smith","year":"2019","journal-title":"Lancet"},{"issue":"6483","key":"10.1016\/j.ijid.2020.09.015_bib0150","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1126\/science.abb2507","article-title":"Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation","volume":"367","author":"Wrapp","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.ijid.2020.09.015_bib0155","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/1743-422X-11-82","article-title":"Antibody-dependent infection of human macrophages by severe acute respiratory syndrome coronavirus","volume":"11","author":"Yip","year":"2014","journal-title":"Virol J"},{"issue":"3 Suppl. 4","key":"10.1016\/j.ijid.2020.09.015_bib0160","first-page":"25","article-title":"Antibody-dependent enhancement of SARS coronavirus infection and its role in the pathogenesis of SARS","author":"Yip","year":"2016","journal-title":"Hong Kong Med J"},{"key":"10.1016\/j.ijid.2020.09.015_bib0165","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.3389\/fmicb.2019.01781","article-title":"Recent advances in the vaccine development against Middle East respiratory syndrome-coronavirus","volume":"10","author":"Yong","year":"2019","journal-title":"Front Microbiol"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971220307311?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971220307311?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T22:56:56Z","timestamp":1738450616000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971220307311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":33,"alternative-id":["S1201971220307311"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2020.09.015","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antibody-dependent enhancement of coronavirus","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2020.09.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}]}}